Abstract: A skin care composition that contains a combination of a vitamin B3 compound, palmitoyl pentapeptide-4, acetyl tetrapeptide-11, and a dermatologically acceptable carrier. The combination of vitamin B3 compound, palmitoyl pentapeptide-4, and acetyl tetrapeptide-11 increases activation of a cell's Antioxidant Response Element (ARE), (e.g., synergistically) to improve a visible sign of skin aging.

Abstract: A skin care composition that contains a combination of a vitamin B3 compound, palmitoyl pentapeptide-4, acetyl tetrapeptide-11, and a dermatologically acceptable carrier. The combination of vitamin B3 compound, palmitoyl pentapeptide-4, and acetyl tetrapeptide-11 increases activation of a cell's Antioxidant Response Element (ARE), (e.g., synergistically) to improve a visible sign of skin aging.

Abstract: A skin care composition that contains a combination of a vitamin B3 compound, palmitoyl pentapeptide-4, acetyl tetrapeptide-11, and a dermatologically acceptable carrier. The combination of vitamin B3 compound, palmitoyl pentapeptide-4, and acetyl tetrapeptide-11 increases activation of a cell's Antioxidant Response Element (ARE), (e.g., synergistically) to improve a visible sign of skin aging.

Abstract: A method and system for classifying different types of periorbital dyschromia is disclosed. The method includes providing at least one of a predetermined imaging characteristic and a biological characteristic for each of three different types of periorbital dyschromia, and then measuring the appropriate characteristic on a person exhibiting periorbital dyschromia. The type of periorbital dyschromia exhibited by a person can then be determined by comparing the measured value to the predetermined value and selecting the corresponding type of periorbital dyschromia.

Abstract: A seismic generation system may include an electrical source, a conductor coupled to the electrical source and to be positioned in a wellbore in a subterranean formation with a casing therein, and a seismic generation source assembly to be positioned in the wellbore and coupled to the conductor. The seismic generation source assembly may include a source element having a sealed housing, an armature within the sealed housing, source electromagnets coupled to the armature, and electromagnetic clamps coupled to the armature, each electromagnetic clamp having opposite magnetic poles. The sealed housing may include respective ferromagnetic portions adjacent the opposite magnetic poles of each electromagnetic clamp, and non-ferromagnetic portions between the opposite magnetic poles of each electromagnetic clamp.

Abstract: A method of mapping a subterranean formation having at least one wellbore therein may include operating an electromagnetic (EM) signal source and an EM receiver to generate wellbore position data. The method may also include operating a seismic signal source and a seismic receiver to generate seismic data, and generating subterranean formation data based upon the wellbore position data and the seismic data.

Abstract: A seismic generation system may include an electrical source, a conductor coupled to the electrical source and to be positioned in a wellbore in a subterranean formation with a casing therein, and a seismic generation source assembly to be positioned in the wellbore and coupled to the conductor. The seismic generation source assembly may include a source element having a sealed housing, an armature within the sealed housing, source electromagnets coupled to the armature, and electromagnetic clamps coupled to the armature, each electromagnetic clamp having opposite magnetic poles. The sealed housing may include respective ferromagnetic portions adjacent the opposite magnetic poles of each electromagnetic clamp, and non-ferromagnetic portions between the opposite magnetic poles of each electromagnetic clamp.

Abstract: Gene panels, biomarker panels and microarrays relating to lipid formation in stratum corneum of human skin as a function of extrinsic and/or intrinsic aging conditions, and methods for assessing the age status of human skin, methods for identifying or evaluating an agent as effective for improving stratum corneum barrier maintenance and/or repair properties in aged skin, and cosmetic composition comprising the identified agents are all provided.

Abstract: The invention provides methods and compositions for screening and identifying peptide aptamers that can modulate a cell phenotype and further, can be used for the treatment of a disease involving a misregulated cell phenotype, such as, for example, a cancer.