Patents by Inventor Bradley Gould
Bradley Gould has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230137976Abstract: An injection device includes a housing having an internal volume and a viewing portion. A movable seal is disposed in the internal volume and is movable from an initial position to an injection end position to urge a drug product out of the housing. An indicator assembly is disposed in the internal volume and includes a dose end indicator. The indicator assembly is biased from a dose remaining position toward a dose end position where the dose end indicator is visible through the viewing portion. A release mechanism releasably holds the indicator assembly in the dose remaining position and is linked to the movable seal such that the movable seal reaching the injection end position causes the release mechanism to release the indicator assembly to the dose end position.Type: ApplicationFiled: August 26, 2022Publication date: May 4, 2023Inventors: Sean Corrigan, Bradley Gould, David T. Andersen, Kelly Burton, Tyler W. Mitchell, Ian Cleathero
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Publication number: 20210063644Abstract: Low-coherence enhanced backscattering (LEBS) spectroscopy is an angular resolved backscattering technique that is sensitive to sub-diffusion light transport length scales in which information about the scattering phase function is preserved. Lens-based and lens-free fiber optic LEBS probes are described that are capable of measuring optical properties of a target tissue through depth-limited measurements of backscattering angles within the enhanced backscattered cone.Type: ApplicationFiled: May 26, 2020Publication date: March 4, 2021Inventors: Vadim Backman, Jeremy D. Rogers, Nikhil N. Mutyal, Bradley Gould, Andrew J. Radosevich, The Quyen Nguyen
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Patent number: 10921212Abstract: An automated calibration system that includes a probe guide and a target assembly. The probe guide receives an optical probe, and the target assembly includes one or more calibration targets. The target assembly is slideable relative to the probe guide so that a first calibration target is aligned under the optical probe in a first position of the target assembly and a second calibration target is aligned under the optical probe in a second position of the target assembly.Type: GrantFiled: June 18, 2018Date of Patent: February 16, 2021Assignees: NORTHWESTERN UNIVERSITY, AMERICAN BIOOPTICS, LLCInventors: Vadim Backman, Bradley Gould, Nikhil Mutyal, Frank Garrett, Jr., The Quyen Nguyen, Michael Garrett
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Publication number: 20210007673Abstract: Methods and apparatus initiate a procedure performed by a probe on tissue. A signal is obtained from the probe, the signal varying with changes in a proximity of the probe to the tissue. The obtained signal is analyzed by a controller to determine whether the probe is within a predetermined distance of the tissue. The controller initiates the procedure when it is determined that the probe is within the predetermined distance of the tissue. The obtaining and analyzing may be repeated until the probe is determined to be within the predetermined distance of the tissue. The analyzing may include comparing the obtained signal to a predetermined threshold.Type: ApplicationFiled: June 21, 2017Publication date: January 14, 2021Inventors: Vadim Backman, David S. Mueller, Andrew J. Cittadine, Sarah Ruderman, Hemant Roy, Bradley Gould
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Patent number: 10881273Abstract: A pre-fabricated, on-demand interface provides optical coupling between disposable and reusable portions of a fiber-optic probe. The interface uses a pre-cured, compressible optically-transmissive gel in a cavity of the disposable portion, which can be a disposable insertion tip of the fiber optic probe. The disposable portion includes an elongated housing, or sheath, and the cavity is located within and proximal of a distal end of the elongated housing. A proximal end of an optical assembly of the disposable portion is located within the cavity and contacts the gel. A first coupling, provided at a proximal end of the elongated housing, detachably couples to a mating, second coupling of the probe reusable portion. When the disposable and reusable portions are coupled together, the gel is compressed between the proximal end of the optical assembly of the disposable portion and a distal optical member of an optical assembly of the reusable portion.Type: GrantFiled: March 4, 2015Date of Patent: January 5, 2021Assignees: Northwestern University, American Biooptics LLCInventors: Vadim Backman, Bradley Gould, Andrew J. Cittadine, Nikhil Mutyal
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Patent number: 10684417Abstract: Low-coherence enhanced backscattering (LEBS) spectroscopy is an angular resolved backscattering technique that is sensitive to sub-diffusion light transport length scales in which information about the scattering phase function is preserved. Lens-based and lens-free fiber optic LEBS probes are described that are capable of measuring optical properties of a target tissue through depth-limited measurements of backscattering angles within the enhanced backscattered cone.Type: GrantFiled: February 1, 2018Date of Patent: June 16, 2020Assignees: NORTHWESTERN UNIVERSITY, AMERICAN BIOOPTICS, LLCInventors: Vadim Backman, Jeremy D. Rogers, Nikhil N. Mutyal, Bradley Gould, Andrew J. Radosevich, The Quyen Nguyen
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Publication number: 20190374722Abstract: An injection device includes a housing having an internal volume and a viewing portion. A movable seal is disposed in the internal volume and is movable from an initial position to an injection end position to urge a drug product out of the housing. An indicator assembly is disposed in the internal volume and includes a dose end indicator. The indicator assembly is biased from a dose remaining position toward a dose end position where the dose end indicator is visible through the viewing portion. A release mechanism releasably holds the indicator assembly in the dose remaining position and is linked to the movable seal such that the movable seal reaching the injection end position causes the release mechanism to release the indicator assembly to the dose end position.Type: ApplicationFiled: June 7, 2019Publication date: December 12, 2019Applicant: AbbVie Inc.Inventors: Sean Corrigan, Bradley Gould, David T. Andersen, Kelly Burton, Tyler W. Mitchell, Ian Cleathero
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Publication number: 20180368691Abstract: An automated calibration system that includes a probe guide and a target assembly. The probe guide receives an optical probe, and the target assembly includes one or more calibration targets. The target assembly is slideable relative to the probe guide so that a first calibration target is aligned under the optical probe in a first position of the target assembly and a second calibration target is aligned under the optical probe in a second position of the target assembly.Type: ApplicationFiled: June 18, 2018Publication date: December 27, 2018Applicant: NORTHWESTERN UNIVERSITYInventors: Vadim BACKMAN, Bradley GOULD, Nikhil MUTYAL, Frank GARRETT, Quyen NGUYEN, Michael GARRETT
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Publication number: 20180180814Abstract: Low-coherence enhanced backscattering (LEBS) spectroscopy is an angular resolved backscattering technique that is sensitive to sub-diffusion light transport length scales in which information about the scattering phase function is preserved. Lens-based and lens-free fiber optic LEBS probes are described that are capable of measuring optical properties of a target tissue through depth-limited measurements of backscattering angles within the enhanced backscattered cone.Type: ApplicationFiled: February 1, 2018Publication date: June 28, 2018Applicants: NORTHWESTERN UNIVERSITY, AMERICAN BIOOPTICS LLCInventors: Vadim Backman, Jeremy D. Rogers, Nikhil N. Mutyal, Bradley Gould, Andrew J. Radosevich
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Patent number: 9885834Abstract: Low-coherence enhanced backscattering (LEBS) spectroscopy is an angular resolved backscattering technique that is sensitive to sub-diffusion light transport length scales in which information about the scattering phase function is preserved. Lens-based and lens-free fiber optic LEBS probes are described that are capable of measuring optical properties of a target tissue through depth-limited measurements of backscattering angles within the enhanced backscattered cone.Type: GrantFiled: August 9, 2013Date of Patent: February 6, 2018Assignees: NORTHWESTERN UNIVERSITY, AMERICAN BIOOPTICS LLCInventors: Vadim Backman, Jeremy D. Rogers, Nikhil N. Mutyal, Bradley Gould, Andrew J. Radosevich
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Publication number: 20160256037Abstract: A pre-fabricated, on-demand interface provides optical coupling between disposable and reusable portions of a fiber-optic probe. The interface uses a pre-cured, compressible optically-transmissive gel in a cavity of the disposable portion, which can be a disposable insertion tip of the fiber optic probe. The disposable portion includes an elongated housing, or sheath, and the cavity is located within and proximal of a distal end of the elongated housing. A proximal end of an optical assembly of the disposable portion is located within the cavity and contacts the gel. A first coupling, provided at a proximal end of the elongated housing, detachably couples to a mating, second coupling of the probe reusable portion. When the disposable and reusable portions are coupled together, the gel is compressed between the proximal end of the optical assembly of the disposable portion and a distal optical member of an optical assembly of the reusable portion.Type: ApplicationFiled: March 4, 2015Publication date: September 8, 2016Inventors: Vadim BACKMAN, Bradley GOULD, Andrew J. CITTADINE, Nikhil MUTYAL
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Publication number: 20140036271Abstract: Low-coherence enhanced backscattering (LEBS) spectroscopy is an angular resolved backscattering technique that is sensitive to sub-diffusion light transport length scales in which infoniiation about the scattering phase function is preserved. Lens-based and lens-free fiber optic LEBS probes are described that are capable of measuring optical properties of a target tissue through depth-limited measurements of backscattering angles within the enhanced backscattered cone.Type: ApplicationFiled: August 9, 2013Publication date: February 6, 2014Inventors: Vadim BACKMAN, Jeremy D. ROGERS, Nikhil N. MUTYAL, Bradley GOULD, Andrew J. RADOSEVICH
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Publication number: 20130084042Abstract: A fiber optic connector has a connector body, an elongated ferrule supported in the connector body, and a sleeve fixed on the circumference of a distal tip of the ferrule. The ferrule has an axial passage that opens on a front surface of the tip so that an endface of a fiber retained in the passage is exposed at the front surface. Further, the sleeve has a leading edge that projects a determined distance axially beyond the front surface of the tip to form a recessed region in which the exposed endface of the fiber is set back from the leading edge of the sleeve. A barrier is contained in the recessed region for protecting the fiber endface from damage by surrounding objects. The barrier may include a cured epoxy layer, a lens, or a refractive index matching material optically aligned with the fiber endface.Type: ApplicationFiled: February 21, 2012Publication date: April 4, 2013Applicant: OFS Fitel, LLCInventors: Kevin G. Bouchard, Mark T. Zmurko, Bradley Gould
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Publication number: 20100262020Abstract: The present invention relates to probe apparatuses and component combinations thereof that are used to recognize possibly abnormal living tissue using a detected early increase in microvascular blood supply and corresponding applications. In one embodiment there is disclosed an apparatus that emits broadband light obtained from a light source onto microvasculature of tissue disposed within a human body and receives interacted light that is obtained from interaction of the broadband light with the microvasculature for transmission to a receiver. Different further embodiments include combinations of optical fibers, polarizers and lenses that assist in the selection of a predetermined depth profile of interacted light. In another embodiment, a kit apparatus is described that has various probe tips and/or light transmission elements that provide for various combinations of predetermined depth profiles of interacted light.Type: ApplicationFiled: January 8, 2010Publication date: October 14, 2010Applicants: American Biooptics LLC, Northshore University Healthsystem, Northwestern UniversityInventors: Vadim Backman, Bradley Gould, Andrew Cittadine, Jeremy Rogers, Hemant Roy
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Publication number: 20080027300Abstract: An oximetry probe assembly includes fluid seal assembly taking the form of a manually actuated plunger which moves relative to a barrel having a seal placed therein. Depression of the plunger causes the seal to be deformed so as to permit insertion of an oximetry probe through the seal and advancement towards a central venous catheter. When the plunger is released, the seal is compressed against the barrel and the sheath of the oximetry probe to thereby form a fluid-tight seal. The plunger and barrel are preferably configured as a one-handed grasping assembly whereby the user may hold the plunger and barrel with one hand, press the plunger with the thumb, and advance the oximetry probe through the fluid seal assembly with the other hand.Type: ApplicationFiled: July 31, 2007Publication date: January 31, 2008Applicant: HOSPIRA, INC.Inventors: Brian Barclay, John Norman, Anis Rahman, William Rudzena, Tage Grant, Bradley Gould, Hrishikesh Choudhury