Abstract: A support for a plurality of cables includes one or more cable separator beams, each with a half-cylindrically-shaped sleeve formed on each end of each beam. A sleeve on one end of each beam is configured to align with a half-cylindrically-shaped end-cap to form an enclosed cylindrical space for passage of one of the plurality of cables. The second half-cylindrically-shaped sleeve on the other end of each beam is configured to align with the corresponding second half-cylindrically-shaped sleeve on the other of the two beams to form another enclosed cylindrical space for passage of another one of the plurality of cables. An elongated flexible fastener has a locking portion on one end thereof that fastens to a tail portion on the other end thereof, configured to surround and fasten the end caps to the beams, and the beams to each other, to secure and support the plurality of cables.

Abstract: The present application relates to aqueous solution compositions of engineered dimeric proteins comprising monomers that comprise at least one human serpin polypeptide operably linked to a human immunoglobulin Fc polypeptide or a polypeptide that is derived from an immunoglobulin Fc polypeptide, at low buffer concentrations and low ionic strength and containing a neutral amino acid. The aqueous solution compositions increase the stability of the an Fc domain in aqueous solution compositions, and in particular increase the stability of an engineered dimeric protein.

Abstract: The invention is based in part on the observation that a CHO cell oxidizing enzyme, particularly QSOX1, can survive a seemingly rigorous antibody purification process to reduce subsequent conjugation efficiency of the antibody to a drug. Whether the oxidizing enzyme survives the purification procedure depends on which purification techniques are employed which can vary from one antibody to another. With knowledge that contamination with a CHO cell oxidizing enzyme is a potential problem for subsequent conjugation, a suitable purification scheme can be devised for any antibody that eliminates or at least reduces CHO oxidizing enzyme(s) to an acceptable level.

Abstract: The invention is based in part on the observation that a CHO cell oxidizing enzyme, particularly QSOX1, can survive a seemingly rigorous antibody purification process to reduce subsequent conjugation efficiency of the antibody to a drug. Whether the oxidizing enzyme survives the purification procedure depends on which purification techniques are employed which can vary from one antibody to another. With knowledge that contamination with a CHO cell oxidizing enzyme is a potential problem for subsequent conjugation, a suitable purification scheme can be devised for any antibody that eliminates or at least reduces CHO oxidizing enzyme(s) to an acceptable level.

Abstract: An intelligent tool is configured to communicate with a wearable computing device to provide information that the wearable computing device uses to generate and/or display augmented reality content to a user of the wearable computing device. The intelligent tool includes a handle for a user to grip an intelligent tool, an engagement portion coupled to the handle, the engagement portion being configured to engage with an object, at least one sensor mounted to the engagement portion, the sensor configured to obtain information associated with the object, and one or more hardware processors in communication with the at least one sensor configured to store the obtained information. The intelligent tool may also include a power source configured to provide electrical power to the at least one sensor and the one or more hardware processors. The intelligent tool may also include a light source that emits a light to illuminate an object.

Abstract: A system for displaying augmented reality content includes an intelligent tool and a wearable-computing device. The intelligent tool is configured to obtain at least one measurement of an object using at least one sensor mounted to the intelligent tool, and communicate the at least one measurement to a device in communication with the intelligent tool. The intelligent tool may further include a camera, and the at least one measurement includes an image acquired with the at least one camera. The intelligent tool may also include a biometric module configured to obtain a biometric measurement from a user of the intelligent tool. One or more modules of the intelligent tool may be powered based on the biometric measurement. The wearable-computing device includes a display affixed to the wearable-computing device, such that augmented reality content based on the obtained at least one measurement is displayed on the display.

Abstract: The invention is based in part on the observation that a CHO cell oxidizing enzyme, particularly QSOX1, can survive a seemingly rigorous antibody purification process to reduce subsequent conjugation efficiency of the antibody to a drug. Whether the oxidizing enzyme survives the purification procedure depends on which purification techniques are employed which can vary from one antibody to another. With knowledge that contamination with a CHO cell oxidizing enzyme is a potential problem for subsequent conjugation, a suitable purification scheme can be devised for any antibody that eliminates or at least reduces CHO oxidizing enzyme(s) to an acceptable level.