Patents by Inventor Bradley Hollidge

Bradley Hollidge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • VECTORIZED ANTI-CGRP AND ANTI-CGRPR ANTIBODIES AND ADMINISTRATION THEREOF
    Publication number: 20240124890
    Abstract: Compositions and methods are described for the delivery of a fully human post-translationally modified therapeutic monoclonal antibody that binds to CGRP or CGRP receptor to a human subject for the treatment or prevention of migraines and cluster headaches. The antibodies may be delivered by gene therapy vectors, particularly rAAV vectors. Also provided are dual transgene constructs for the delivery of anti-CGRP and anti-CGRP receptor antibodies or antigen binding fragments thereof.
    Type: Application
    Filed: October 28, 2021
    Publication date: April 18, 2024
    Inventors: Jared Smith, Bradley Hollidge, Joseph Bruder, Ye Liu, Randolph Qian, Chunping Qiao