Patents by Inventor Bradley J. Herberich

Bradley J. Herberich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7700593
    Abstract: The present invention comprises a new class of compounds useful for the prophylaxis and treatment of protein kinase mediated diseases, including inflammation and related conditions. The compounds have a general Formula I wherein A, B, R1, R2, R3 and R4 are defined herein. The invention also comprises pharmaceutical compositions including one or more compounds of Formula I, uses of such compounds and compositions for treatment of P38 map kinase mediated diseases including rheumatoid arthritis, psoriasis and other inflammation disorders, as well as intermediates and processes useful for the preparation of compounds of Formula I.
    Type: Grant
    Filed: October 5, 2007
    Date of Patent: April 20, 2010
    Assignee: Amgen Inc.
    Inventors: Dawei Zhang, Andrew Tasker, Kelvin K. C. Sham, Partha Pratim Chakrabarti, James Richard Falsey, Bradley J. Herberich, Liping H. Pettus, Robert M. Rzasa
  • Publication number: 20090149468
    Abstract: The present invention relates to therapeutic diazobicyclo pyridines and their use in the treatment of arthritis, rheumatoid arthritis, psoriatic arthritis or osteoarthritis, organ transplant, acute transplant or heterograft and homograft rejection, ischemic and reperfusion injury, transplantation tolerance induction, multiple sclerosis, inflammatory bowel disease, ulcerative colitis, Crohn's disease, lupus, graft vs.
    Type: Application
    Filed: February 4, 2009
    Publication date: June 11, 2009
    Applicant: Amgen Inc.
    Inventors: Guo-Qiang Cao, Jian J. Chen, Celia Dominguez, Anthony Reed, Kelvin K.C. Sham, Maya C. Thaman, Dawei Zhang, Bradley J. Herberich
  • Publication number: 20080161303
    Abstract: The present invention comprises a new class of compounds useful for the prophylaxis and treatment of protein kinase mediated diseases, including inflammation and related conditions. The compounds have a general Formula I wherein A, B, R1, R2, R3 and R4 are defined herein. The invention also comprises pharmaceutical compositions including one or more compounds of Formula I, uses of such compounds and compositions for treatment of P38 map kinase mediated diseases including rheumatoid arthritis, psoriasis and other inflammation disorders, as well as intermediates and processes useful for the preparation of compounds of Formula I.
    Type: Application
    Filed: October 5, 2007
    Publication date: July 3, 2008
    Applicant: Amgen Inc.
    Inventors: Dawei Zhang, Andrew Tasker, Kelvin K.C. Sham, Partha Pratim Chakrabarti, James Richard Falsey, Bradley J. Herberich, Liping H. Pettus, Robert M. Rzasa