Patents by Inventor Bradley James Sumrow

Bradley James Sumrow has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR THE USE OF A PD-1 X CTLA-4 BISPECIFIC MOLECULE
    Publication number: 20230312756
    Abstract: The present invention is directed in part to dosing regimens for administering a PD-1×CTLA-4 bispecific molecule for the treatment of cancer, and other conditions. The invention is directed in part to the use of such molecules, and to the use of pharmaceutical compositions and pharmaceutical kits that contain such molecules and that facilitate the use of such dosing regimens in the treatment of cancer or to stimulate immune cells.
    Type: Application
    Filed: July 23, 2021
    Publication date: October 5, 2023
    Inventors: Bradley James SUMROW, Ezio BONVINI, Sharad SHARMA, Jon Marc WIGGINTON, Alexey Yevgenyevich BEREZHNOY
  • Therapy for the Treatment of Cancer
    Publication number: 20230056230
    Abstract: The present invention is directed to regimens for administering one or more Antibody-Based Molecules that bind PD-1 or PD-L1, and LAG-3 (e.g, a PD-1×LAG-3 bispecific molecule) alone, or in combination with an Antibody-Based Molecule that binds a Tumor Antigen (TA) for the treatment of cancer. The invention particularly concerns the use of such regimens in conjunction with PD-1×LAG-3 bispecific molecules. The invention is directed to the use of such molecules, and to the use of pharmaceutical compositions and pharmaceutical kits that contain such molecules and that facilitate the use of such dosing regimens in the treatment of cancer.
    Type: Application
    Filed: December 18, 2020
    Publication date: February 23, 2023
    Applicant: MacroGenics, Inc.
    Inventors: Bradley James Sumrow, Ross La Motte-Mohs, Jon Marc Wigginton, Ezio Bonvini, Paul A. Moore, Scott Koenig, Xiaoyu Zhang
  • ANTI-PD-1 ANTIBODIES AND USES THEREOF
    Publication number: 20200095322
    Abstract: Methods of treatment of cancer with antibodies and antibody fragments that bind to PD-1 are disclosed.
    Type: Application
    Filed: June 18, 2019
    Publication date: March 26, 2020
    Inventors: Mark Cornfeld, Naimish Bharat Pandya, Jon Marc Wigginton, Ross La Motte-Mohs, Bradley James Sumrow