Patents by Inventor Bradley Margus

Bradley Margus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090006128
    Abstract: Improved life sciences business systems and methods are disclosed. One or more genomes are scanned for single nucleotide polymorphisms. The polymorphisms are used in association studies for pharmaceutical and diagnostic developments. In certain embodiments, an association study comprises both genotyping of these polymorphisms and resequencing of genomic regions that contain polymorphisms associated with a phenotypic state of interest.
    Type: Application
    Filed: July 3, 2007
    Publication date: January 1, 2009
    Applicant: Perlegen Sciences, Inc.
    Inventors: Bradley A. Margus, David A. Cox
  • Patent number: 7427480
    Abstract: Improved life sciences business systems and methods are disclosed. One or more genomes are scanned for single nucleotide polymorphisms. The polymorphisms are assigned to haplotype blocks, and representative SNPs from the haplotype blocks are used in association studies for pharmaceutical and diagnostic developments.
    Type: Grant
    Filed: July 13, 2005
    Date of Patent: September 23, 2008
    Assignee: Perlegen Sciences, Inc.
    Inventors: Bradley A Margus, David R Cox
  • Patent number: 7335474
    Abstract: Methods and systems for identifying biological marker-placebo effect correlations are provided. Clinical trial design and data analysis of clinical trial data is modified to accommodate marker-placebo effect correlations.
    Type: Grant
    Filed: September 13, 2004
    Date of Patent: February 26, 2008
    Assignee: Perlegen Sciences, Inc.
    Inventors: Bradley Margus, David Cox, Jesse Hsu
  • Patent number: 7135286
    Abstract: Improved pharmaceutical and diagnostic business systems and methods are disclosed. One or more genomes are scanned for single nucleotide polymorphisms. The polymorphisms are assigned to haplotype blocks, and representative SNPs from the haplotype blocks are used in association studies for pharmaceutical and diagnostic development.
    Type: Grant
    Filed: March 26, 2002
    Date of Patent: November 14, 2006
    Assignee: Perlegen Sciences, Inc.
    Inventors: Bradley A. Margus, David R. Cox, Stephen P. A. Fodor
  • Publication number: 20060008834
    Abstract: Improved life sciences business systems and methods are disclosed. One or more genomes are scanned for single nucleotide polymorphisms. The polymorphisms are assigned to haplotype blocks, and representative SNPs from the haplotype blocks are used in association studies for pharmaceutical and diagnostic developments.
    Type: Application
    Filed: July 13, 2005
    Publication date: January 12, 2006
    Applicant: Perlegen Sciences, Inc.
    Inventors: Bradley Margus, David Cox
  • Patent number: 6955883
    Abstract: Improved life sciences business systems and methods are disclosed. One or more genomes are scanned for single nucleotide polymorphisms. The polymorphisms are assigned to haplotype blocks, and representative SNPs from the haplotype blocks are used in association studies for pharmaceutical and diagnostic developments.
    Type: Grant
    Filed: March 26, 2003
    Date of Patent: October 18, 2005
    Assignee: Perlegen Sciences, Inc.
    Inventors: Bradley A. Margus, David R. Cox, Stephen P. A. Fodor
  • Patent number: 6897025
    Abstract: Improved systems and methods for performing genetic analyses. Full genomic DNA scans are performed on the genetic DNA from a plurality of individuals to identify genetic variants. For those variants, but not based on a full genetic DNA scan, the variants alone are scanned in additional individuals to identify blocks of the variants that tend to be inherited together.
    Type: Grant
    Filed: January 7, 2002
    Date of Patent: May 24, 2005
    Assignee: Perlegen Sciences, Inc.
    Inventors: David R. Cox, Bradley A. Margus, Nila Patil
  • Publication number: 20050079532
    Abstract: Methods and systems for identifying biological marker-placebo effect correlations are provided. Clinical trial design and data analysis of clinical trial data is modified to accommodate marker-placebo effect correlations.
    Type: Application
    Filed: September 13, 2004
    Publication date: April 14, 2005
    Applicant: Perlegen Sciences, Inc.
    Inventors: Bradley Margus, David Cox, Jesse Hsu
  • Publication number: 20040091890
    Abstract: Improved life sciences business systems and methods are disclosed. One or more genomes are scanned for single nucleotide polymorphisms. The polymorphisms are assigned to haplotype blocks, and representative SNPs from the haplotype blocks are used in association studies for pharmaceutical and diagnostic developments.
    Type: Application
    Filed: March 26, 2003
    Publication date: May 13, 2004
    Applicant: Perlegen Sciences, Inc.
    Inventors: Bradley A. Margus, David R. Cox, Stephen P.A. Fodor
  • Publication number: 20030186244
    Abstract: Improved pharmaceutical and diagnostic business systems and methods are disclosed. One or more genomes are scanned for single nucleotide polymorphisms. The polymorphisms are assigned to haplotype blocks, and representative SNPs from the haplotype blocks are used in association studies for pharmaceutical and diagnostic development.
    Type: Application
    Filed: March 26, 2002
    Publication date: October 2, 2003
    Applicant: Perlegen Sciences, Inc.
    Inventors: Bradley A. Margus, David R. Cox, Stephen P.A. Fodor
  • Publication number: 20030157488
    Abstract: Improved systems and methods for performing genetic analyses. Full genomic DNA scans are performed on the genetic DNA from a plurality of individuals to identify genetic variants. For those variants, but not based on a full genetic DNA scan, the variants alone are scanned in additional individuals to identify blocks of the variants that tend to be inherited together.
    Type: Application
    Filed: January 7, 2002
    Publication date: August 21, 2003
    Applicant: Perlegen Sciences, Inc.
    Inventors: David R. Cox, Bradley A. Margus