Abstract: The present disclosure provides compounds of Formula (I): or a pharmaceutically acceptable salt, solvate, or tautomer thereof, and uses of the same in treating a disease or disorder (e.g., cancer or fibrosis).

Abstract: The present application generally relates to identifying gene clusters from long-read genomic sequencing data. The disclosure provides methods, non-transitory computer readable media, and apparatuses for processing long-read genomic sequencing data, performing error corrections, and identifying gene cluster, e.g. biosynthetic gene clusters. The methods, non-transitory computer readable media, and apparatuses described herein can be employed in broad areas of biological applications, such as drug discovery, industrial chemical discovery and production, and basic biological research.