Abstract: The disclosure provides a way to supplement the tidal volume delivered to the patient by a leaking re-breather when the delivered volume becomes less than that set by the ventilator (in either pressure-regulated or volume modes). This may be accomplished with a shunt—a gas conduit joining the non-patient side of the re-breather to the patient side. A low-resistance, plenum or a draw-over vaporizer may also be incorporated into the gas pathway. Such a device may include a housing with a movable partition separating an actuating side from a patient side. The housing includes a ventilator orifice for pneumatic communication between a ventilator and the actuating side and a patient orifice for pneumatic communication between the patient side and a patient. A shunt defines a bypass flow path from the actuating side and to the patient side when the moveable partition is at a maximal displacement towards the patient side.

Abstract: The disclosure provides a way to supplement the tidal volume delivered to the patient by a leaking re-breather when the delivered volume becomes less than that set by the ventilator (in either pressure-regulated or volume modes). This may be accomplished with a shunt—a gas conduit joining the non-patient side of the re-breather to the patient side. A low-resistance, plenum or a draw-over vaporizer may also be incorporated into the gas pathway. Such a device may include a housing with a movable partition separating an actuating side from a patient side. The housing includes a ventilator orifice for pneumatic communication between a ventilator and the actuating side and a patient orifice for pneumatic communication between the patient side and a patient. A shunt defines a bypass flow path from the actuating side and to the patient side when the moveable partition is at a maximal displacement towards the patient side.

Abstract: A method and system for an endotracheal tube or tracheostomy a tube formed with a hole, a cuff connected to the tube and formed around the hole, and a skirt connected to the tube above the cuff and draped over the cuff. A coating of a hydrophobic, lipophobic, and oleophobic substance can be disposed on the interior and exterior surface of the tube, the cuff, and the skirt. A stylet and siring may be used to secure the skirt during insertion in a detachable fashion. The string is retractable on withdrawal of the stylet.

Abstract: A device, system, and method for isolating a ventilator from one or more patients in which the delivery conditions of gas delivered to an isolation device from a ventilator may drive the delivery of breathing-gas delivered to one or more patients, the breathing-gas having the same or different delivery conditions. In one embodiment, an isolation device may have a housing and a movable partition. The movable partition may be joined to the housing, The movable partition may have a patient side on a first side of the partition and an actuating side on a second side of the partition. The isolation device may include an inlet pressure regulator on the actuating side and/or an exhaust pressure regulator on the patient side. These regulators may alter the delivery conditions (including, but not limited to, pressure and volume) of breathing-gas delivered to a patient.

Abstract: A method and system for an endotracheal tube or tracheostomy a tube formed with a hole, a cuff connected to the tube and formed around the hole, and a skirt connected to the tube above the cuff and draped over the cuff. A coating of a hydrophobic, lipophobic, and oleophobic substance can be disposed on the interior and exterior surface of the tube, the cuff, and the skirt. A stylet and siring may be used to secure the skirt during in-sertion in a detachable fashion. The string is retractable on withdrawal of the stylet.

Abstract: A device, system, and method for isolating a ventilator from one or more patients in which the delivery conditions of gas delivered to an isolation device from a ventilator may drive the delivery of breathing-gas delivered to one or more patients, the breathing-gas having the same or different delivery conditions. In one embodiment, an isolation device may have a housing and a movable partition. The movable partition may be joined to the housing, The movable partition may have a patient side on a first side of the partition and an actuating side on a second side of the partition. The isolation device may include an inlet pressure regulator on the actuating side and/or an exhaust pressure regulator on the patient side. These regulators may alter the delivery conditions (including, but not limited to, pressure and volume) of breathing-gas delivered to a patient.

Abstract: A device, system, and method for isolating a ventilator from one or more patients in which the delivery conditions of gas delivered to an isolation device from a ventilator may drive the delivery of breathing-gas delivered to one or more patients, the breathing-gas having the same or different delivery conditions. In one embodiment, an isolation device may have a housing and a movable partition. The movable partition may be joined to the housing, The movable partition may have a patient side on a first side of the partition and an actuating side on a second side of the partition. The isolation device may include an inlet pressure regulator on the actuating side and/or an exhaust pressure regulator on the patient side. These regulators may alter the delivery conditions (including, but not limited to, pressure and volume) of breathing-gas delivered to a patient.

Abstract: A gas delivery system and a method of delivering gas are disclosed. In one such system there is a housing and a displaceable partition. The housing may be divided by the partition into a respirator side and a patient side. The partition may have one or more holes extending through the partition to allow gas to move from one side of the partition to the other side of the partition.

Abstract: The invention includes a partial gas separator, which may include a housing and a movable divider in the housing. A method according to the invention may provide a partial gas separator and gas may be moved to or from the housing. While moving gas to or from the housing, the movable divider may be allowed to move with the flow of gas.

Abstract: A device, system, and method for isolating a ventilator from one or more patients in which the delivery conditions of gas delivered to an isolation device from a ventilator may drive the delivery of breathing-gas delivered to one or more patients, the breathing-gas having the same or different delivery conditions. In one embodiment, an isolation device may have a housing and a movable partition. The movable partition may be joined to the housing, The movable partition may have a patient side on a first side of the partition and an actuating side on a second side of the partition. The isolation device may include an inlet pressure regulator on the actuating side and/or an exhaust pressure regulator on the patient side. These regulators may alter the delivery conditions (including, but not limited to, pressure and volume) of breathing-gas delivered to a patient.

Abstract: Breathing-gas delivery systems and methods are described. In one such system there is a movable partition, a housing and a filter body. The housing is disposed about the movable partition, and thereby provides a respirator side on a first side of the partition, and a patient side on a second side of the partition. The housing also has (a) a patient inspiration orifice on the patient side, which is adaptable to supply breathing-gas to a patient, and (b) a gas exhaust orifice on the patient side.

Abstract: A method of delivering a particulate therapeutic agent is disclosed. Such a method may include providing a carbon dioxide scrubber in pneumatic communication with the respiratory system of a patient. Gas and particulate therapeutic agent expired by the patient are passed through the scrubber to provide treated gas, and the treated gas and particulate therapeutic agent are provided back to the respiratory system.

Abstract: Isolation devices and methods of controlling a partition are disclosed. Devices according to the invention have a housing disposed about a movable partition. The housing has respirator and patient sides on respective first and second sides of the partition. The housing also has: (a) a respirator orifice on the respirator side, adaptable to be in pneumatic communication with a respirator; (b) a patient inspiration orifice on the patient side, adaptable to be in pneumatic communication with a patient; (c) a bias inflow orifice on the patient side, adaptable to be in pneumatic communication with a source of inspiratory gas; and, (d) an expiration return orifice on the patient side. The devices may further include a partition position sensor, a CO2 scrubber, and a controller operable to regulate gas flow to the bias inflow orifice based on partition position.

Abstract: A gas delivery system and a method of delivering gas are disclosed. In one such system there is a housing and a displaceable partition. The housing may be divided by the partition into a respirator side and a patient side. The partition may have one or more holes extending through the partition to allow gas to move from one side of the partition to the other side of the partition.

Abstract: A device and method of ventilating a patient reduces the bias flow relative to existing oscillatory ventilators. The device has a gas flow circuit including an oscillating line, a patient line and an exhalation or a return line. A gas supply line and an outlet valve are in pneumatic communication with the gas flow circuit. One or more CO2 scrubbers and one or more check valves are provided in the circuit. A method of ventilating using such a device is also disclosed.

Abstract: Disclosed are methods for reducing the injury to tissues, cells, microorganisms or lipids caused by free radicals. The method comprises exposing a composition comprising perfluorocarbon to the tissue, cell, microorganism or lipids in need of such a treatment. Perfluorocarbons may be used neat in solutions, as gases or as emulsions.

Abstract: An isolation device is disclosed. The isolation device may have a movable partition and a housing disposed about the movable partition. The isolation device may have a partition biaser joined to the partition, and a CO2 scrubber. A method of delivering inspiratory gas to a patient is also disclosed.

Abstract: A particulate therapeutic agent delivery device and method are disclosed. In an embodiment of the device there is a respiratory-gas channel having a patient end to which a patient may be pneumatically connected, a particulate-therapeutic-agent channel in pneumatic communication with the respiratory-gas channel, a scrubber housing in pneumatic communication with the respiratory-gas channel, the scrubber housing having an expired-gas orifice for receiving expired gas from the respiratory-gas-channel, and a scrubber material situated within the housing so as to receive expired gas via the expired-gas orifice and remove carbon dioxide from the expired gas to provide treated gas, and situated so as to provide the treated gas to the respiratory-gas channel.

Abstract: A device and method of ventilating a patient reduces the bias flow relative to existing oscillatory ventilators. The device has a gas flow circuit comprising an oscillating line, a patient line and an exhalation or a return line. A gas supply line is and an outlet valve are in pneumatic communication with the gas flow circuit. One or more CO2 scrubbers and one or more check valves are provided in the circuit. A method of ventilating using such a device is also disclosed.

Abstract: A device and method of ventilating a patient reduces the bias flow relative to existing oscillatory ventilators. The device has an oscillator, and an oscillating line having a first end in sealing relationship with the oscillator. A gas supply line is connected to the oscillating line, and a patient line is connected to a second end of the oscillating line. An outlet valve is in pneumatic communication with the patient line. A method of ventilating using such a device is also disclosed.