Abstract: This invention relates to compounds of Formula (I): and enantiomers thereof, and to pharmaceutically acceptable salts of Formula (I) and said enantiomers, wherein L1, L2, R1, R2, R3 and n are as defined herein. The invention further relates to pharmaceutical compositions comprising such compounds and salts, and to methods and uses of such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer, in a subject in need thereof.

Abstract: Methods and apparatus consistent with the invention provide the ability to organize, index, search, and present time series data based on searches. Time series data are sequences of time stamped records occurring in one or more usually continuous streams, representing some type of activity. In one embodiment, time series data is stored as discrete events time stamps. A search is received and relevant event information is retrieved based in whole or in part on the time stamp, a keyword indexing mechanism, or statistical indices calculated at the time of the search.

Abstract: A substrate processing apparatus includes a vacuum chamber with a processing zone for processing a substrate using plasma and at least one magnetic field source configured to generate one or more active magnetic fields through the processing zone. The apparatus also includes a magnetic field sensor configured to detect a signal representing the one or more active magnetic fields, and a controller coupled to the magnetic field sensor, and the at least one magnetic field source. The controller is configured to detect a target value corresponding to at least one characteristic of the one or more active magnetic fields, set an initial current through the at least one magnetic field source, the initial current corresponding to the target value; and adjust a subsequent current through the at least one magnetic field source based on the detected signal representing the one or more active magnetic fields.

Abstract: A unit for mixing and dispensing an aerosol precursor composition, and containers to be dispensed therefrom. The unit includes a plurality of bulk material filling stations, the plurality of bulk material filling stations have at least one first filling station with aerosol former and at least one second filling station with a flavor material for creating the aerosol precursor. The unit also includes a bulk consumable pack staging a plurality of containers configured to receive the aerosol precursor, and a robot configured to retrieve a container from the bulk consumable pack and move the container through at least two dimensions to stop at at least two of the plurality of bulk material filling stations.

Abstract: A unit for mixing and dispensing an aerosol precursor composition, and containers to be dispensed therefrom. The unit includes a plurality of bulk material filling stations, the plurality of bulk material filling stations have at least one first filling station with aerosol former and at least one second filling station with a flavor material for creating the aerosol precursor. The unit also includes a bulk consumable pack staging a plurality of containers configured to receive the aerosol precursor, and a robot configured to retrieve a container from the bulk consumable pack and move the container through at least two dimensions to stop at at least two of the plurality of bulk material filling stations.

Abstract: A robotic system includes a robotic arm, a base couple coupled to the robotic arm, and a controller. The robotic supports a work implement and is configured to move the work implement to perform an operation on a workpiece. The base is configured to be removably coupled to a mounting surface. The controller is in communication with the robotic arm, the work implement, and the base. Further, the controller is configured to disable the operation of at least one of the robotic arm and the work implement if a coupling parameter between the base and the mounting surface is below a threshold value.

Abstract: A unit for mixing and dispensing an aerosol precursor composition, and containers to be dispensed therefrom. The unit includes a plurality of bulk material filling stations, the plurality of bulk material filling stations have at least one first filling station with aerosol former and at least one second filling station with a flavor material for creating the aerosol precursor. The unit also includes a bulk consumable pack staging a plurality of containers configured to receive the aerosol precursor, and a robot configured to retrieve a container from the bulk consumable pack and move the container through at least two dimensions to stop at at least two of the plurality of bulk material filling stations.

Abstract: A unit for mixing and dispensing an aerosol precursor composition, and containers to be dispensed therefrom. The unit includes a plurality of bulk material filling stations, the plurality of bulk material filling stations have at least one first filling station with aerosol former and at least one second filling station with a flavor material for creating the aerosol precursor. The unit also includes a bulk consumable pack staging a plurality of containers configured to receive the aerosol precursor, and a robot configured to retrieve a container from the bulk consumable pack and move the container through at least two dimensions to stop at least two of the plurality of bulk material filling stations.

Abstract: An example process includes: powering, via a power supply, an active-matrix display panel comprised of picture elements; and identifying, based on an output of the power supply, one or more picture elements in the active-matrix display panel that are potentially defective. The example process may also include identifying, among one or more of the picture elements that are potentially-defective, one or more picture elements that actually are defective.

Abstract: A robotic system includes a robotic arm, a base couple coupled to the robotic arm, and a controller. The robotic supports a work implement and is configured to move the work implement to perform an operation on a workpiece. The base is configured to be removably coupled to a mounting surface. The controller is in communication with the robotic arm, the work implement, and the base. Further, the controller is configured to disable the operation of at least one of the robotic arm and the work implement if a coupling parameter between the base and the mounting surface is below a threshold value.

Abstract: An example process includes: powering, via a power supply, an active-matrix display panel comprised of picture elements; and identifying, based on an output of the power supply, one or more picture elements in the active-matrix display panel that are potentially defective. The example process may also include identifying, among one or more of the picture elements that are potentially-defective, one or more picture elements that actually are defective.

Abstract: A system for manufacturing a component includes a power supply unit adapted to generate welding power. The system also includes a welding system. The welding system includes a welding torch having a welding wire. The welding wire is movable in an axial direction and a radial direction with respect to a central axis of the welding torch for depositing material from the welding wire to manufacture the component. The welding system also includes a motion control assembly. The motion control assembly is adapted to move the welding wire in the radial direction. The system further includes a control unit configured to transmit control signals to the welding system for controlling at least one of a rotation speed of the welding wire, a diameter of rotation of the welding wire, a direction of rotation of the welding wire, and a iced rate of the welding wire.

Abstract: An example method performed for a circuit path includes: receiving signals in the circuit path; and controlling states of the signals in the circuit path based on skews produced by circuits electrically connected in series in the circuit path. The states are controlled by inverting or not inverting the signals in the circuit path so that skews produced by different circuits in the circuit paths at least partially cancel.

Abstract: A unit for mixing and dispensing an aerosol precursor composition, and containers to be dispensed therefrom. The unit includes a plurality of bulk material filling stations, the plurality of bulk material filling stations have at least one first filling station with aerosol former and at least one second filling station with a flavor material for creating the aerosol precursor. The unit also includes a bulk consumable pack staging a plurality of containers configured to receive the aerosol precursor, and a robot configured to retrieve a container from the bulk consumable pack and move the container through at least two dimensions to stop at least two of the plurality of bulk material filling stations.

Abstract: A ladder with supplementary support legs is an apparatus that provides increased stability when compared to traditional stepladders. The apparatus includes a left support mechanism, a right support mechanism, and a front set of rungs. The left support mechanism and the right support mechanism are identical halves of the apparatus. Each support mechanism includes a ladder rail, a bracing leg, and a pivoting outrigger. The ladder rail and bracing leg are hinged together and are able to move between an expanded and collapsed configuration. The outrigger pivots away from the ladder rail and bracing leg to create a tripod between the three legs. The front set of rungs functions as steps which are connected between the ladder rails of the left support mechanism and the right support mechanism.

Abstract: Example circuitry includes: a first sampling circuit configured to operate based on a first clock signal, to receive data, and to sample the data, where the first clock signal is calibrated to compensate for a first timing error in a rising edge of the data; a second sampling circuit configured to operate based on a second clock signal, to receive the data, and to sample the data, where the second first clock signal is calibrated to compensate for a second timing error in a falling edge of the data; and a third sampling circuit to receive the data and a third clock signal, to sample the data based on the third clock signal to produce sampled data, and to control an output of the circuitry based on the sampled data to be either an output of the first sampling circuit or an output of the second sampling circuit.

Abstract: A computer-controlled method includes an electronic device receiving online survey results from a question of an online survey and an electronic display visually presenting to a user the online survey results over a total period of time. The visually presenting can include visually presenting a representation of the number of online survey results that corresponds with each answer in connection with a discrete period of time within the total period of time. Each result can be visually identified by a corresponding identifier.

Abstract: Calibrating test equipment may include: aligning timing of a first group of channels in the test equipment; aligning timing of a second group of channels in the test equipment, with the second group of channels being different from the first group of channels; determining a misalignment in timing between a first channel and a second channel, with the first channel being from the first group of channels, and the second channel being from the second group of channels; and compensating, for the misalignment, channels in at least one of the first group or the second group.

Abstract: Calibrating test equipment may include: aligning timing of a first group of channels in the test equipment; aligning timing of a second group of channels in the test equipment, with the second group of channels being different from the first group of channels; determining a misalignment in timing between a first channel and a second channel, with the first channel being from the first group of channels, and the second channel being from the second group of channels; and compensating, for the misalignment, channels in at least one of the first group or the second group.

Abstract: A drop generator operable to selectively form a drop having a first size and a drop having a second size from liquid emitted through a nozzle associated with the drop generator. The drop having the first size and the drop having the second size travel along a drop trajectory with the first size being larger than the second size when compared to each other. Each of the drops has a drop velocity. A gas flow deflection system includes a gas flow that is directed at a deflection zone that comprises at least a portion of the drop trajectory. The gas flow in the deflection zone includes a velocity vector having a parallel velocity component and a perpendicular velocity component with the parallel velocity component and the perpendicular velocity component being defined relative to the drop trajectory.