Patents by Inventor Bradley R. Kelemen

Bradley R. Kelemen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160201104
    Abstract: Disclosed are a number of homologs and variants of Hypocrea jecorina Ce17A (formerly Trichoderma reesei cellobiohydrolase I or CBH1), nucleic acids encoding the same and methods for producing the same. The homologs and variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted and/or deleted.
    Type: Application
    Filed: December 10, 2013
    Publication date: July 14, 2016
    Applicant: DANISCO US INC.
    Inventors: Richard R. BOTT, Maria FOUKARAKI, Ronaldus Wilhelmus HOMMES, Thijs KAPER, Bradley R. KELEMEN, Slavko KRALJ, Igor NIKOLAEV, Mats SANDGREN, Johannes Franciscus Thomas VAN LIESHOUT, SANDER VAN STIGT THANS
  • Publication number: 20160186155
    Abstract: Disclosed are glycosyl hydrolase enzyme variants, particularly variants of certain oxidoreductases of glycosyl hydrolase family 61. Nucleic acids encoding the glycosyl hydrolyase variants, compositions including the glycosyl hydrolase variants, methods of producing the variants, and methods of using the variants are also described.
    Type: Application
    Filed: July 24, 2014
    Publication date: June 30, 2016
    Inventors: Nicholai DOUGLAS, Maria FOUKARAKI, Ronaldus Wilhelmus HOMMES, Thijs KAPER, Bradley R. KELEMEN, Slavko KRALJ, SUZANNE E. LANTZ, Jonathan K. LASSILA, Igor NIKOLAEV, Daniel Esteban TORRES-PAZMINO, Wilhelmus VAN DER KLEY, Johannes Franciscus Thomas VAN LIESHOUT, SANDER VAN STIGT THANS
  • Publication number: 20160177279
    Abstract: The present disclosure is generally directed to glycosyl hydrolase enzymes, compositions comprising such enzymes, and methods of using the enzymes and compositions, for example for the saccharification of cellulosic and hemicellulosic materials into sugars.
    Type: Application
    Filed: July 27, 2015
    Publication date: June 23, 2016
    Applicant: DANISCO US INC.
    Inventors: Benjamin BOWER, Megan Yee HSI, Thijs KAPER, Bradley R. KELEMEN, Suzanne E. LANTZ, Edmund A. LARENAS, Colin MITCHINSON, Steven KIM, William D. HITZ, Mark EMPTAGE, Keith Dumont WING
  • Publication number: 20160177281
    Abstract: Disclosed are glycosyl hydrolase enzyme variants, particularly variants of certain oxidoreductases of glycosyl hydrolase family 61. Nucleic acids encoding the glycosyl hydrolyase variants, compositions including the glycosyl hydrolase variants, methods of producing the variants, and methods of using the variants are also described.
    Type: Application
    Filed: July 24, 2014
    Publication date: June 23, 2016
    Inventors: Maria FOUKARAKI, Ronaldus Wilhelmus HOMMES, Thijs KAPER, Bradley R. KELEMEN, Slavko KRALJ, SUZANNE E. LANTZ, IGOR NIKOLAEV, Wilhelmus VAN DER KLEY, Johan Franciscus Thomas VAN LIESHOUT, SANDER VAN STIGT THANS
  • Publication number: 20160168550
    Abstract: Disclosed are glycosyl hydrolase enzyme variants, particularly variants of certain oxidoreductases of glycosyl hydrolase family 61. Nucleic acids encoding the glycosyl hydrolyase variants, compositions including the glycosyl hydrolase variants, methods of producing the variants, and methods of using the variants are also described.
    Type: Application
    Filed: July 24, 2014
    Publication date: June 16, 2016
    Inventors: Maria FOUKARAKI, Ronaldus Wilhelmus HOMMES, Thijs KAPER, Bradley R. KELEMEN, Slavko KRALJ, SUZANNE E. LANTZ, IGOR NIKOLAEV, Wilhelmus VAN DER KLEY, Johannes Franciscus Thomas VAN LIESHOUT, SANDER VAN STIGT THANS
  • Publication number: 20160122735
    Abstract: Disclosed are a number of homologs and variants of Hypocrea jecorina Cel7A (formerly Trichoderma reesei cellobiohydrolase I or CBH1), nucleic acids encoding the same and methods for producing the same. The homologs and variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted and/or deleted.
    Type: Application
    Filed: December 10, 2013
    Publication date: May 5, 2016
    Applicant: Danisco US Inc.
    Inventors: Richard R. BOTT, Maria FOUKARAKI, Ronaldus Wilhelmus HOMMES, Thijs KAPER, Bradley R. KELEMEN, Slavko KRALJ, Igor NIKOLAEV, Mats SANDGREN, Johannes Franciscus Thomas VAN LIESHOUT, Sander VAN STIGT THANS
  • Publication number: 20160122734
    Abstract: Disclosed are a number of homologs and variants of Hypocrea jecorina Cel7A (formerly Trichoderma reesei cellobiohydrolase I or CBH1), nucleic acids encoding the same and methods for producing the same. The homologs and variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted and/or deleted.
    Type: Application
    Filed: December 10, 2013
    Publication date: May 5, 2016
    Applicant: DANISCO US INC.
    Inventors: Richard R. BOTT, Maria FOUKARAKI, Ronaldus Wilhelmus HOMMES, Thijs KAPER, Bradley R. KELEMEN, Slavko KRALJ, Igor NIKOLAEV, Mats SANDGREN, Johannes Franciscus Thomas VAN LIESHOUT, SANDER VAN STIGT THANS
  • Publication number: 20150329842
    Abstract: The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having reduced binding to non-cellulosic materials. Also described are nucleic acids encoding the cellulase, compositions comprising said cellulase, methods of identifying cellulose variants and methods of using the compositions.
    Type: Application
    Filed: March 19, 2015
    Publication date: November 19, 2015
    Applicant: Danisco US Inc.
    Inventors: Luis CASCAO-PEREIRA, Thijs KAPER, Bradley R. KELEMEN, Amy D. LIU
  • Publication number: 20150315560
    Abstract: Disclosed are a number of homologs and variants of Hypocrea jecorina Cel7A (formerly Trichoderma reesei cellobiohydrolase I or CBH1), nucleic acids encoding the same and methods for producing the same. The homologs and variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted and/or deleted.
    Type: Application
    Filed: December 10, 2013
    Publication date: November 5, 2015
    Applicant: Danisco US Inc.
    Inventors: Richard R. BOTT, Maria FOUKARAKI, Ronaldus Wilhelmus HOMMES, Thijs KAPER, Bradley R. KELEMEN, Slavko KRALJ, Igor NIKOLAEV, Mats SANDGREN, Johannes Franciscus Thomas VAN LIESHOUT, SANDER VAN STIGT THANS
  • Patent number: 8999692
    Abstract: The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having reduced binding to non-cellulosic materials. Also described are nucleic acids encoding the cellulase, compositions comprising said cellulase, methods of identifying cellulose variants and methods of using the compositions.
    Type: Grant
    Filed: July 6, 2012
    Date of Patent: April 7, 2015
    Assignee: Danisco US Inc.
    Inventors: Luis G. Cascao-Pereira, Thijs Kaper, Bradley R. Kelemen, Amy D. Liu
  • Publication number: 20140302585
    Abstract: The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having improved expression, activity and/or stability. Also described are nucleic acids encoding the cellulase variants, compositions comprising the cellulase variants, and methods of use thereof.
    Type: Application
    Filed: February 25, 2014
    Publication date: October 9, 2014
    Applicant: DANISCO US INC.
    Inventors: Wolfgang AEHLE, Richard R. BOTT, Benjamin S. BOWER, Jonathan CASPI, David A. ESTELL, Frits GOEDEGEBUUR, Ronaldus Wilhelmus HOMMES, Thijs KAPER, Bradley R. KELEMEN, Slavko KRALJ, Johannes Franciscus Thomas VAN LIESHOUT, Igor NIKOLAEV, Sander VAN STIGT THANS, Louise WALLACE, Gudrun VOGTENTANZ, Mats SANDGREN
  • Publication number: 20140134677
    Abstract: The present invention relates to compositions that can be used in hydrolyzing biomass such as compositions comprising a polypeptide having glycosyl hydrolase family 61/endoglucanase activity, methods for hydrolyzing biomass material, and methods for reducing viscosity of biomass mixture using a composition comprising a polypeptide having glycosyl hydrolase family 61/endoglucanase activity.
    Type: Application
    Filed: March 16, 2012
    Publication date: May 15, 2014
    Applicant: DANISCO US INC.
    Inventors: Colin Mitchinson, Mian Li, Bradley R. Kelemen, Suzanne E. Lantz, Keith D. Wing, William D. Hitz
  • Publication number: 20140085998
    Abstract: The present invention provides a solid material comprising an immobilized mixture of two or more proteorhodopsins, two or more bacteriorhodopsins, or one or more bacteriorhodopsin and one or more proteorhodopsins. The proteorhodopsins are selected from the group consisting of all-trans-retinal-containing proteorhodopsins and retinal analog-containing proteorhodopsins; all of which have absorption spectra that do not overlap. The bacteriorhodopsins are selected from the group consisting of all-trans-retinal-containing bacteriorhodopsins and retinal analog-containing bacteriorhodopsins; all of which have absorption spectra that do not overlap. The present invention also provides an optical information carrier, such as an optical data storage material and a fraud-proof optical data carrier, comprising the above-described solid material and a substrate selected from the group consisting of glass, paper, metal, fabric material, and plastic material, wherein said solid material is deposited on said substrate.
    Type: Application
    Filed: August 23, 2013
    Publication date: March 27, 2014
    Applicant: Danisco US Inc.
    Inventors: Richard R. Bott, Rasmus B. Jensen, Bradley R. Kelemen, Donald E. Ward II, Gregory M. Whited
  • Publication number: 20140011242
    Abstract: The present teachings provide methods of converting cellulosic materials to soluble sugars. Methods for increasing the yield of glucose from the enzymatic saccharification of cellulosic materials is also provided. The present teachings further provide methods of increasing the yield of cellobiose from the enzymatic saccharification of cellulosic materials.
    Type: Application
    Filed: June 13, 2013
    Publication date: January 9, 2014
    Applicant: Danisco US Inc.
    Inventors: Bradley R. KELEMEN, Edmund A. LARENAS, Colin MITCHINSON
  • Publication number: 20130149742
    Abstract: The present disclosure relates to filamentous fungal host strains and recombinant DNA constructs for creation and use thereof. The filamentous fungal host strains are particularly useful for achieving reliable expression of recombinant enzymes and variants.
    Type: Application
    Filed: June 3, 2011
    Publication date: June 13, 2013
    Applicant: Danisco US Inc.
    Inventors: Benjamin S. Bower, Thijs Kaper, Bradley R. Kelemen
  • Patent number: 8372953
    Abstract: The present invention provides a solid material comprising an immobilized mixture of two or more proteorhodopsins, two or more bacteriorhodopsins, or one or more bacteriorhodopsin and one or more proteorhodopsins. The proteorhodopsins are selected from the group consisting of all-trans-retinal-containing proteorhodopsins and retinal analog-containing proteorhodopsins; all of which have absorption spectra that do not overlap. The bacteriorhodopsins are selected from the group consisting of all-trans-retinal-containing bacteriorhodopsins and retinal analog-containing bacteriorhodopsins; all of which have absorption spectra that do not overlap. The present invention also provides an optical information carrier, such as an optical data storage material and a fraud-proof optical data carrier, comprising the above-described solid material and a substrate selected from the group consisting of glass, paper, metal, fabric material, and plastic material, wherein said solid material is deposited on said substrate.
    Type: Grant
    Filed: July 12, 2011
    Date of Patent: February 12, 2013
    Assignee: Danisco US Inc.
    Inventors: Richard R. Bott, Rasmus B. Jensen, Bradley R. Kelemen, Donald E. Ward, II, Gregory M. Whited
  • Publication number: 20120276595
    Abstract: The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having reduced binding to non-cellulosic materials. Also described are nucleic acids encoding the cellulase, compositions comprising said cellulase, methods of identifying cellulose variants and methods of using the compositions.
    Type: Application
    Filed: July 6, 2012
    Publication date: November 1, 2012
    Applicant: DANISCO US INC.
    Inventors: Luis G. Cascao-Pereira, Thijs Kaper, Bradley R. Kelemen, Amy D. Liu
  • Patent number: 8236542
    Abstract: The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having reduced binding to non-cellulosic materials. Also described are nucleic acids encoding the cellulase, compositions comprising said cellulase, methods of identifying cellulose variants and methods of using the compositions.
    Type: Grant
    Filed: June 3, 2009
    Date of Patent: August 7, 2012
    Assignee: Danisco US Inc.
    Inventors: Luis G. Cascao-Pereira, Thijs Kaper, Bradley R Kelemen, Amy D. Liu
  • Publication number: 20120010333
    Abstract: The present invention provides a solid material comprising an immobilized mixture of two or more proteorhodopsins, two or more bacteriorhodopsins, or one or more bacteriorhodopsin and one or more proteorhodopsins. The proteorhodopsins are selected from the group consisting of all-trans-retinal-containing proteorhodopsins and retinal analog-containing proteorhodopsins; all of which have absorption spectra that do not overlap. The bacteriorhodopsins are selected from the group consisting of all-trans-retinal-containing bacteriorhodopsins and retinal analog-containing bacteriorhodopsins; all of which have absorption spectra that do not overlap. The present invention also provides an optical information carrier, such as an optical data storage material and a fraud-proof optical data carrier, comprising the above-described solid material and a substrate selected from the group consisting of glass, paper, metal, fabric material, and plastic material, wherein said solid material is deposited on said substrate.
    Type: Application
    Filed: July 12, 2011
    Publication date: January 12, 2012
    Inventors: Richard R. Bott, Rasmus B. Jensen, Bradley R. Kelemen, Donald E. Ward, II, Gregory M. Whited
  • Patent number: 7982000
    Abstract: The present invention provides a solid material comprising an immobilized mixture of two or more proteorhodopsins, two or more bacteriorhodopsins, or one or more bacteriorhodopsin and one or more proteorhodopsins. The proteorhodopsins are selected from the group consisting of all-trans-retinal-containing proteorhodopsins and retinal analog-containing proteorhodopsins; all of which have absorption spectra that do not overlap. The bacteriorhodopsins are selected from the group consisting of all-trans-retinal-containing bacteriorhodopsins and retinal analog-containing bacteriorhodopsins; all of which have absorption spectra that do not overlap. The present invention also provides an optical information carrier, such as an optical data storage material and a fraud-proof optical data carrier, comprising the above-described solid material and a substrate selected from the group consisting of glass, paper, metal, fabric material, and plastic material, wherein said solid material is deposited on said substrate.
    Type: Grant
    Filed: June 9, 2005
    Date of Patent: July 19, 2011
    Assignee: Danisco US Inc.
    Inventors: Richard R. Bott, Rasmus B. Jensen, Bradley R. Kelemen, Donald E. Ward, II, Gregory M. Whited