Patents by Inventor BRADLEY S. CULBERT
BRADLEY S. CULBERT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240232924Abstract: An aspiration system includes an elongate tubular member having a lumen; an aspiration catheter configured to be inserted through the lumen of the elongate tubular member, and including a tubular aspiration member having a proximal end, a distal end, and a lumen, and configured to at least partially extend out of the lumen of the elongate tubular member at the distal end of the elongate tubular member; an elongate support member coupled to the tubular aspiration member and extending between a proximal end of the aspiration catheter and the proximal end of the tubular aspiration member; and an annular sealing member coupled to the tubular aspiration member and configured to create a seal against an inner surface of the elongate tubular member, when a vacuum sufficient to cause aspiration is actively applied to the lumen of the elongate tubular member.Type: ApplicationFiled: March 19, 2024Publication date: July 11, 2024Inventors: David M. Look, Bradley S. Culbert
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Patent number: 12002065Abstract: An aspiration system includes an elongate tubular member having a lumen; an aspiration catheter configured to be inserted through the lumen of the elongate tubular member, and including a tubular aspiration member having a proximal end, a distal end, and a lumen, and configured to at least partially extend out of the lumen of the elongate tubular member at the distal end of the elongate tubular member; an elongate support member coupled to the tubular aspiration member and extending between a proximal end of the aspiration catheter and the proximal end of the tubular aspiration member; and an annular sealing member coupled to the tubular aspiration member and configured to create a seal against an inner surface of the elongate tubular member, when a vacuum sufficient to cause aspiration is actively applied to the lumen of the elongate tubular member.Type: GrantFiled: December 22, 2020Date of Patent: June 4, 2024Assignee: Incuvate, LLCInventors: David M. Look, Bradley S. Culbert
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Publication number: 20240050111Abstract: A system for aspiration includes an aspiration catheter including an elongate shaft including an aspiration lumen, and an open distal end, an extension tube, the lumen of the extension tube configured to be hydraulically coupled to the aspiration lumen, a peristaltic pump configured for driving fluid through the extension tube, a compressible portion disposed between the distal end and the proximal end of the extension tube, the compressible portion configured to be coupled to the peristaltic pump, such that operation of the peristaltic pump drives fluid from the aspiration lumen from the distal end of the extension tube to the proximal end of the extension tube, and a controller configured to receive a first signal from the first sensor and configured to vary the operation of the peristaltic pump based at least in part on a first signal received from a first sensor coupled to the aspiration lumen or extension tube related to a change in the characteristic of flow.Type: ApplicationFiled: October 17, 2023Publication date: February 15, 2024Inventors: Bradley S. Culbert, David M. Look, Gary Carlson
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Publication number: 20230389946Abstract: A system for removal of blood or thrombus includes an aspiration catheter having an elongate shaft including an aspiration lumen having proximal end configured to couple to a vacuum source, and a distal end having an orifice, an elongate member configured for placement through the aspiration lumen and having a distal portion including a disruption element configured to disrupt thrombus within the aspiration lumen, and a monitoring device configured for removable connection in between the aspiration catheter and the vacuum source, and including a housing, a pressure sensor in fluid communication with an interior of the housing, a measurement device coupled to the pressure sensor and configured for measuring deviations in fluid pressure, and a communication device coupled to the measurement device and configured to generate an alert signal when a deviation in fluid pressure measured by the measurement device exceeds a pre-set threshold.Type: ApplicationFiled: August 16, 2023Publication date: December 7, 2023Inventors: David M. Look, Bradley S. Culbert
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Patent number: 11826064Abstract: A system for aspiration includes an aspiration catheter including an elongate shaft including an aspiration lumen, and an open distal end, an extension tube, the lumen of the extension tube configured to be hydraulically coupled to the aspiration lumen, a peristaltic pump configured for driving fluid through the extension tube, a compressible portion disposed between the distal end and the proximal end of the extension tube, the compressible portion configured to be coupled to the peristaltic pump, such that operation of the peristaltic pump drives fluid from the aspiration lumen from the distal end of the extension tube to the proximal end of the extension tube, and a controller configured to receive a first signal from the first sensor and configured to vary the operation of the peristaltic pump based at least in part on a first signal received from a first sensor coupled to the aspiration lumen or extension tube related to a change in the characteristic of flow.Type: GrantFiled: May 29, 2020Date of Patent: November 28, 2023Assignee: Incuvate, LLCInventors: Bradley S. Culbert, David M. Look, Gary Carlson
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Publication number: 20230355257Abstract: A system for real time monitoring of catheter aspiration includes a pressure sensor configured for placement in fluid communication with a lumen which at least partially includes an aspiration lumen of a catheter, the aspiration lumen configured to couple to a vacuum source, a measurement device coupled to the pressure sensor and configured for measuring deviations in fluid pressure, and a communication device coupled to the measurement device and configured to generate a continuous signal which is proportional to measured fluid pressure.Type: ApplicationFiled: July 15, 2023Publication date: November 9, 2023Inventors: David M. Look, Bradley S. Culbert
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Patent number: 11771445Abstract: A system for removal of blood or thrombus includes an aspiration catheter having an elongate shaft including an aspiration lumen having proximal end configured to couple to a vacuum source, and a distal end having an orifice, an elongate member configured for placement through the aspiration lumen and having a distal portion including a disruption element configured to disrupt thrombus within the aspiration lumen, and a monitoring device configured for removable connection in between the aspiration catheter and the vacuum source, and including a housing, a pressure sensor in fluid communication with an interior of the housing, a measurement device coupled to the pressure sensor and configured for measuring deviations in fluid pressure, and a communication device coupled to the measurement device and configured to generate an alert signal when a deviation in fluid pressure measured by the measurement device exceeds a pre-set threshold.Type: GrantFiled: June 8, 2021Date of Patent: October 3, 2023Assignee: Incuvate, LLCInventors: David M. Look, Bradley S. Culbert
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Patent number: 11744600Abstract: A system for real time monitoring of catheter aspiration includes a pressure sensor configured for placement in fluid communication with a lumen which at least partially includes an aspiration lumen of a catheter, the aspiration lumen configured to couple to a vacuum source, a measurement device coupled to the pressure sensor and configured for measuring deviations in fluid pressure, and a communication device coupled to the measurement device and configured to generate a continuous signal which is proportional to measured fluid pressure.Type: GrantFiled: May 26, 2020Date of Patent: September 5, 2023Assignee: Incuvate, LLCInventors: David M. Look, Bradley S. Culbert
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Publication number: 20230270457Abstract: In one embodiment, system for real time monitoring of catheter aspiration includes a housing having a first port adapted for connection to a vacuum source and a second port adapted for connection with an aspiration catheter, a pressure sensor in fluid communication with an interior of the housing, a measurement device coupled to the pressure sensor and configured for measuring deviations in fluid pressure, and a communication device coupled to the measurement device and configured to generate an alert signal when a deviation in fluid pressure measured by the measurement device exceeds a pre-set threshold. In another embodiment, the system for real time monitoring of catheter aspiration further includes a vacuum source for connection to the first port and an aspiration catheter having an aspiration lumen for connection to the second port.Type: ApplicationFiled: May 5, 2023Publication date: August 31, 2023Inventors: David M. Look, Bradley S. Culbert
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Patent number: 11678905Abstract: A method for improving a flow condition through a catheter inserting a distal end of a sheath within the vasculature of a subject, placing the aspiration catheter through the sheath and advancing the aspiration catheter such that an open distal end of the aspiration lumen is distal to a distal end of the sheath and is in proximity to a thrombus within a blood vessel of a subject, coupling an extension conduit in fluid communication with a lumen of the sheath to a second fluid source, and activating a pump such that pressurized fluid from the first fluid source is applied to the supply lumen of the aspiration catheter, wherein when an active flowing condition is not present, fluid from the second fluid source is caused to flow through the lumen of the sheath.Type: GrantFiled: July 18, 2019Date of Patent: June 20, 2023Assignee: WALK VASCULAR, LLCInventors: David M. Look, Bradley S. Culbert
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Patent number: 11678896Abstract: In one embodiment, system for real time monitoring of catheter aspiration includes a housing having a first port adapted for connection to a vacuum source and a second port adapted for connection with an aspiration catheter, a pressure sensor in fluid communication with an interior of the housing, a measurement device coupled to the pressure sensor and configured for measuring deviations in fluid pressure, and a communication device coupled to the measurement device and configured to generate an alert signal when a deviation in fluid pressure measured by the measurement device exceeds a pre-set threshold. In another embodiment, the system for real time monitoring of catheter aspiration further includes a vacuum source for connection to the first port and an aspiration catheter having an aspiration lumen for connection to the second port.Type: GrantFiled: February 17, 2020Date of Patent: June 20, 2023Assignee: Incuvate, LLCInventors: David M. Look, Bradley S. Culbert
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Patent number: 11672561Abstract: A method for treating a patient having thrombus includes providing a manipulation device including a housing configured to be supported by the hand of a user and having a distal and proximal end, a drive system disposed within the housing, and configured to rotate a rotation member, an engagement member coupled to the rotation member and configured to be removably coupled to an elongate medical device, an activation member carried by the housing such that it can be operated by at least a portion of the hand of the user when the housing is supported by the hand of the user, the drive system configured to apply motive force to the engagement member, securing an elongate member to the engagement member, introducing at least the distal end of the elongate member into a blood vessel adjacent a thrombus, operating the activation member to cause at least some rotation of the rotation member, which in turn causes at least some rotation of the distal end of the elongate member at or near the thrombus, and aspirating aType: GrantFiled: December 19, 2019Date of Patent: June 13, 2023Assignee: WALK VASCULAR, LLCInventors: David M. Look, Bradley S. Culbert
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Publication number: 20230090845Abstract: An aspiration system includes an aspiration catheter including a tubular aspiration member having a proximal end, a distal end, and a lumen, and configured to at least partially extend out of the lumen of an elongate tubular member and into the vasculature of a subject, an elongate support member coupled to the tubular aspiration member and extending between the proximal end of the aspiration catheter and the proximal end of the tubular aspiration member, a high pressure injection lumen extending within the elongate support member and having a distal end including a curved portion configured to change a direction of fluid flow by at least about 90°, at least one orifice located at the distal end of the high pressure injection lumen configured to allow liquid to be released into the lumen of the tubular aspiration member, and an annular seal carried by the tubular aspiration member and configured to create a liquid seal against the inner surface of the elongate tubular member.Type: ApplicationFiled: November 28, 2022Publication date: March 23, 2023Inventors: DAVID M. LOOK, BRADLEY S. CULBERT
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Publication number: 20230035295Abstract: A system for closing a blood vessel includes a housing having a proximal end and a distal end and configured to be held in the hand of a user, an elongate body extending from the distal end of the housing, a distal housing having a proximal end coupled to a distal end of the elongate body and having a cavity including an opening on a side of the distal housing, a lumen passing through the elongate body and terminating at the cavity of the distal housing and configured to couple to a vacuum source, a sensor carried by the distal housing adjacent the cavity and configured for identifying a blood vessel, wherein the lumen is configured to maintain a vacuum within the cavity when a probe having a vessel closure module is inserted within the lumen and the vessel closure module is within the cavity.Type: ApplicationFiled: October 10, 2022Publication date: February 2, 2023Inventors: BRADLEY S. CULBERT, BARTOSZ BOJANOWSKI, ERIC ROWSON
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Publication number: 20230018792Abstract: An extension conduit for use with a system for aspirating thrombus includes a passageway extending between a distal end and a proximal end of the extension conduit, and a combined hydraulic and electrical control carried on the extension conduit and configured to be activated by a user to activate an electric switch while opening a valve to allow flow through the passageway.Type: ApplicationFiled: August 11, 2022Publication date: January 19, 2023Inventors: Bradley S. Culbert, Thanh Van Nguyen, Caroline Kim
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Patent number: 11540847Abstract: An aspiration system includes an aspiration catheter including a tubular aspiration member having a proximal end, a distal end, and a lumen, and configured to at least partially extend out of the lumen of an elongate tubular member and into the vasculature of a subject, an elongate support member coupled to the tubular aspiration member and extending between the proximal end of the aspiration catheter and the proximal end of the tubular aspiration member, a high pressure injection lumen extending within the elongate support member and having a distal end including a curved portion configured to change a direction of fluid flow by at least about 90°, at least one orifice located at the distal end of the high pressure injection lumen configured to allow liquid to be released into the lumen of the tubular aspiration member, and an annular seal carried by the tubular aspiration member and configured to create a liquid seal against the inner surface of the elongate tubular member.Type: GrantFiled: July 8, 2019Date of Patent: January 3, 2023Assignee: Incuvate, LLCInventors: David M. Look, Bradley S. Culbert
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Publication number: 20220387072Abstract: A system for treating a patient having thrombus including an aspiration catheter having an aspiration lumen configured to be coupled to a vacuum source and configured for aspirating thrombus therethrough, an elongate member having a straight distal portion configured to extend from the aspiration lumen into a thrombus within the blood vessel, and a manipulation device selectively coupled to the elongate member, the manipulation device being configured to apply motive force to the elongate member, wherein the motive force comprises a combination of motive force components comprising an alternating clockwise motion and counter-clockwise motion.Type: ApplicationFiled: August 15, 2022Publication date: December 8, 2022Inventors: David M. Look, Bradley S. Culbert
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Publication number: 20220387753Abstract: A system for aspirating thrombus including an aspiration catheter having a supply lumen, an aspiration lumen, and a first connector hydraulically coupled to the proximal end of the aspiration lumen, and a pressure sensor having an internal passageway and having a distal connector configured to hydraulically couple to the first connector, a proximal connector configured to couple to a vacuum source, and a valve disposed between the distal connector and the proximal connector, the valve having an open state and a closed state.Type: ApplicationFiled: August 11, 2022Publication date: December 8, 2022Inventors: David M. Look, Bradley S. Culbert
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Publication number: 20220387052Abstract: A method for improving a flow condition through a catheter advancing an aspiration catheter through a sheath such that an open distal end of the aspiration lumen of the aspiration catheter is distal to a distal end of a sheath and is in proximity to a thrombus within a blood vessel of a subject, coupling an extension conduit in fluid communication with a lumen of the sheath to a fluid source, and activating a pump such that pressurized fluid from a first fluid source is supplied to a supply lumen of the aspiration catheter and when insufficient flowable material is present adjacent the open distal end of the aspiration lumen, fluid from the second fluid source is caused to flow through the lumen of the sheath.Type: ApplicationFiled: August 11, 2022Publication date: December 8, 2022Inventors: David M. Look, Bradley S. Culbert
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Publication number: 20220387752Abstract: A method for removing thrombus from a patient that includes providing an aspiration catheter including a supply lumen and an aspiration lumen, with a connector hydraulically coupled to the proximal end of the aspiration lumen, the connector having an interior cavity, a proximal end and a distal end. The method further includes coupling or causing to couple the supply lumen of the aspiration catheter to a fluid source, coupling or causing to couple the aspiration lumen of the aspiration catheter to a vacuum source, and coupling or causing to couple a pump for injecting fluid from the fluid source through the supply lumen and through the opening into the aspiration lumen. The method includes setting a pump with a control unit such that an input pressure of the supply lumen is between about 650 pounds per square inch and about 1200 pounds per square inch.Type: ApplicationFiled: August 11, 2022Publication date: December 8, 2022Inventors: David M. Look, Bradley S. Culbert