Abstract: The present disclosure provides methods for identifying chemical diverter material placed in a borehole region and provides chemical diverter material. In one embodiment, a method for detecting diverter material placed in a borehole region includes (a) obtaining a first data set by: emitting pulses of neutrons from the pulsed neutron source into the borehole region and detecting capture gamma rays resulting from nuclear reactions in the borehole region; (b) placing a diverter material comprising aqueous-swellable particles and a thermal neutron absorbing material into the borehole region; (c) obtaining a second data set by: emitting pulses of neutrons from the first pulsed neutron source or a second pulsed neutron source into the borehole region, and detecting capture gamma rays in the borehole; and (d) comparing the first data set and the second data set to determine the location of diverter material placed in the borehole region.

Abstract: The present disclosure provides methods for identifying chemical diverter material placed in a borehole region and provides chemical diverter material. In one embodiment, a method for detecting diverter material placed in a borehole region includes (a) obtaining a first data set by: emitting pulses of neutrons from the pulsed neutron source into the borehole region and detecting capture gamma rays resulting from nuclear reactions in the borehole region; (b) placing a diverter material comprising aqueous-swellable particles and a thermal neutron absorbing material into the borehole region; (c) obtaining a second data set by: emitting pulses of neutrons from the first pulsed neutron source or a second pulsed neutron source into the borehole region, and detecting capture gamma rays in the borehole; and (d) comparing the first data set and the second data set to determine the location of diverter material placed in the borehole region.

Abstract: The present disclosure provides methods for identifying chemical diverter material placed in a borehole region and provides chemical diverter material. In one embodiment, a method for detecting diverter material placed in a borehole region includes (a) obtaining a first data set by: emitting pulses of neutrons from the pulsed neutron source into the borehole region and detecting capture gamma rays resulting from nuclear reactions in the borehole region; (b) placing a diverter material comprising aqueous-swellable particles and a thermal neutron absorbing material into the borehole region; (c) obtaining a second data set by: emitting pulses of neutrons from the first pulsed neutron source or a second pulsed neutron source into the borehole region, and detecting capture gamma rays in the borehole; and (d) comparing the first data set and the second data set to determine the location of diverter material placed in the borehole region.

Abstract: Cigarette smoking is a primary determinant of chronic obstructive pulmonary disease (COPD), which is the fourth leading cause of morbidity and mortality in the United States. Unique proteins associated with COPD capable of differentiating subjects likely to experience rapid (RPD) or slow (SLW) decline in lung function have been identified using comprehensive high-throughput proteomic approaches. Thirty peptides, which mapped to 21 unique proteins, were linearly associated with annualized rates of lung function decline among smokers with COPD characterized as having rapid or slow decline and smokers without COPD. Using three different statistical approaches to assess the data, the RPD and SLW groups are differentiated by 55 peptides, which mapped to 33 unique proteins. A number of the identified peptides are proteolytic fragments of proteins that are involved in the complement and/or coagulation systems, have anti-protease activity, or metabolic functions.

Abstract: The technology provided herein relates to the SNPs identified as described herein, both singly and in combination, as well as to the use of these SNPs, and others in linkage disequilibrium with these SNPs, for diagnosis, prediction of clinical course, and/or treatment response for pulmonary disease such as COPD, development of new treatments for pulmonary disease such as COPD based upon comparison of the variant and normal versions of the gene or gene product, and development of cell-culture based and animal models for research and treatment of pulmonary disease such as COPD. The technology provided herein further relates to novel compounds, pharmaceutical compositions, and kits for use in the diagnosis, treatment, and evaluation of such disorders.

Abstract: The invention is directed to a system to separably connect a multiple of containers to each other. Each of the containers has a cover lid press-fitted thereon. Each of the cover lids has diametrically opposed extensions thereon. One of the extensions has a downward lug thereon. The opposite extension has an opening therein to accommodate the lug of the opposite extension. In order to connect two of more containers to each other the lug on one of the lids is inserted into the opening of the adjacent lid and pressed therein. Thereby two or more adjacent containers may be connected to each other but can be separated by removing the lug on one of the lids from the opening in the adjacent lid.

Abstract: Disclosed is a test device for determining the presence or integrity of a biologic comprising a sample pad for receiving the biologic, a conjugate pad, and a test membrane comprising at least one test line comprising an immobilized mimetope, and methods of using the same.

Abstract: A method and system for generating fixed transit routes is provided. A first set of street network segments within a first threshold distance from a starting point is identified for a pattern inputted by a user. A proxy first point along each of the street network segments in the first set is also identified. A second set of street network segments within a second threshold distance from an ending point is identified for the pattern inputted by the user. A proxy second point along each of the street network segments in the second set is also identified. A best path for the pattern is determined including any one of the proxy first points along the street network segments in the first set and any one of the proxy second points along the street network segments in the second set.

Abstract: A method and system for generating fixed transit routes is provided. A first set of street network segments within a first threshold distance from a starting point is identified for a pattern inputted by a user. A proxy first point along each of the street network segments in the first set is also identified. A second set of street network segments within a second threshold distance from an ending point is identified for the pattern inputted by the user. A proxy second point along each of the street network segments in the second set is also identified. A best path for the pattern is determined including any one of the proxy first points along the street network segments in the first set and any one of the proxy second points along the street network segments in the second set.

Abstract: A method and system for generating fixed transit routes is provided. A first set of street network segments within a first threshold distance from a starting point is identified for a pattern inputted by a user. A proxy first point along each of the street network segments in the first set is also identified. A second set of street network segments within a second threshold distance from an ending point is identified for the pattern inputted by the user. A proxy second point along each of the street network segments in the second set is also identified. A best path for the pattern is determined including any one of the proxy first points along the street network segments in the first set and any one of the proxy second points along the street network segments in the second set.

Abstract: Cigarette smoking is a primary determinant of chronic obstructive pulmonary disease (COPD), which is the fourth leading cause of morbidity and mortality in the United States. Unique proteins associated with COPD capable of differentiating subjects likely to experience rapid (RPD) or slow (SLW) decline in lung function have been identified using comprehensive high-throughput proteomic approaches. Thirty peptides, which mapped to 21 unique proteins, were linearly associated with annualized rates of lung function decline among smokers with COPD characterized as having rapid or slow decline and smokers without COPD. Using three different statistical approaches to assess the data, the RPD and SLW groups are differentiated by 55 peptides, which mapped to 33 unique proteins. A number of the identified peptides are proteolytic fragments of proteins that are involved in the complement and/or coagulation systems, have anti-protease activity, or metabolic functions.

Abstract: The technology provided herein relates to the SNPs identified as described herein, both singly and in combination, as well as to the use of these SNPs, and others in linkage disequilibrium with these SNPs, for diagnosis, prediction of clinical course, and/or treatment response for pulmonary disease such as COPD, development of new treatments for pulmonary disease such as COPD based upon comparison of the variant and normal versions of the gene or gene product, and development of cell-culture based and animal models for research and treatment of pulmonary disease such as COPD. The technology provided herein further relates to novel compounds, pharmaceutical compositions, and kits for use in the diagnosis, treatment, and evaluation of such disorders.

Abstract: A method and system for generating fixed transit routes is provided. A first set of street network segments within a first threshold distance from a starting point is identified for a pattern inputted by a user. A proxy first point along each of the street network segments in the first set is also identified. A second set of street network segments within a second threshold distance from an ending point is identified for the pattern inputted by the user. A proxy second point along each of the street network segments in the second set is also identified. A best path for the pattern is determined including any one of the proxy first points along the street network segments in the first set and any one of the proxy second points along the street network segments in the second set.

Abstract: A system and method are disclosed that provide for processing certification data. The system and method include determining a rating definition associated with an engine configuration, and associating an arrangement number with the rating definition. In addition, the system and method include associating a certification type with the arrangement number, and associating a certification dataset, created by recording emissions test results of one or more emissions data parameters, with the rating definition to generate a certification family. The one or more emissions data parameters are included in at least one of an emissions law or an emissions regulation.

Abstract: A fluid for use in a subterranean formation penetrated by a wellbore, the fluid comprising: (a) water; (b) an orthoester; and (c) a surfactant comprising a tertiary alkyl amine ethoxylate generally represented by the following formula: (CH2—CH2—O)XH R—N<(CH2—CH2—O)YH wherein R is an alkyl group or aryl group, and wherein X and Y are each independently at least one. A method of fracturing a subterranean formation, comprising the step of forming a foamed fracturing fluid comprising water; an orthoester; a surfactant comprising a tertiary alkyl amine ethoxylate generally represented by the formula above; and a gas. The method also provides the step of introducing the foamed fracturing fluid into a subterranean formation at a pressure sufficient to create a fracture in the subterranean formation.

Abstract: This invention relates to the use of degradable fibers, and more particularly, to self-degrading fibers and their associated methods of use and manufacture. In one embodiment, the present invention provides a self degrading fiber comprising: an outer shell, and a core liquid.

Abstract: The present disclosure addressed apparatus and methods for forming an annular isolator in a borehole after installation of production tubing. Annular seal means are carried in or on production tubing as it is run into a borehole. In conjunction with expansion of the tubing, the seal is deployed to form an annular isolator. An inflatable element carried on the tubing may be inflated with a fluid carried in the tubing and forced into the inflatable element during expansion of the tubing. Reactive chemicals may be carried in the tubing and injected into the annulus to react with each other and ambient fluids to increase in volume and harden into an annular seal. An elastomeric sleeve, ring or band carried on the tubing may be expanded into contact with a borehole wall and may have its radial dimension increased in conjunction with tubing expansion to form an annular isolator.