Patents by Inventor Bradley W. FOULK

Bradley W. FOULK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR ASSESSING EFFICACY OF MALT1 INHIBITORS USING AN NF-KB TRANSLOCATION ASSAY
    Publication number: 20210156865
    Abstract: Methods and reagents for determining treatment efficacy of a MALT1 inhibitor in a human subject are described. The method involves determining NF-?B nuclear translocation in stimulated PBMCs of a blood sample obtained from the subject. The method provides information for guiding treatment decisions for those subjects receiving a MALT1 inhibitor therapy, improves the accuracy of optimizing therapy, reduces toxicity, and/or monitors the efficacy of therapeutic treatment.
    Type: Application
    Filed: November 20, 2020
    Publication date: May 27, 2021
    Inventors: Alexander Babich, Sriram Balasubramanian, Jing Cao, Gourav Choudhary, Bradley W. Foulk, Liat Izhak, Ulrike Philippar, Nele Vloemans
  • NF-KB REGULATED GENE EXPRESSION ASSAY FOR ASSESSING EFFICACY OF MALT1 INHIBITORS
    Publication number: 20210155990
    Abstract: Methods and reagents for determining treatment efficacy of a MALT1 inhibitor in a human subject are described. The method involves determining MALT1 regulated gene expression in stimulated PBMCs of a blood sample obtained from the subject. The method provides information for guiding treatment decisions for those subjects receiving a MALT1 inhibitor therapy, improves the accuracy of optimizing therapy, reduces toxicity, and/or monitors the efficacy of therapeutic treatment.
    Type: Application
    Filed: November 20, 2020
    Publication date: May 27, 2021
    Inventors: Alexander BABICH, Sriram BALASUBRAMANIAN, Jing CAO, Bradley W. FOULK, Brendan HODKINSON, Liat IZHAK, Ulrike PHILIPPAR, Nele VLOEMANS