Abstract: Implementations of the present disclosure are directed to providing remote access to electronic documents stored in a server system using a virtual secure room, and include actions of authenticating a user at least partially based on credentials of the user, at least partially in response to authenticating the user, providing a secure connection between a computing device of the user and the server system, transmitting at least one electronic document for display to the user on the computing device, monitoring the user, while the at least one electronic document is displayed to the user on the computing device, and selectively closing the secure connection in response to one or more of at least one activity and at least one state of the user.

Abstract: Provided herein are methods to synthesize compounds useful in the treatment of cancer where such compounds comprise a quinazolinyl core moiety and at least one stereoisomeric or atropisomeric moiety.

Abstract: A system and method for determining polarization in a plurality of documents, which may be grouped in a variety of ways, for example according to publication source. The polarization may be determined according to an analysis of the document itself and/or of the publication source of the document. Optionally, topic modeling is performed on one or more documents from one or more sources as part of the above analysis. One or more topic models may then be applied for tagging one or more such documents.

Abstract: An article and method for using the same is disclosed. The article is worn on a user's head and secures a mask to the user's face without requiring loops associated with the mask to be worn over the back of the ears of the user, thereby eliminating strain and discomfort on the user's ears.

Abstract: Embodiments of a system and method for identifying and prioritizing company prospects by training at least one classifier on client company win/loss metrics. One or more classifiers can be trained on a training database compiled from company win/loss database for a client and firmographic data from a robust business entity database. Once trained, the system can employ Artificial Intelligence powered by the trained classifiers to classify and output customized prospect lists of thousands of profiled and scored companies that the AI has determined are likely targets for specific marketing and sales. The AI can also ingest databases of client targets and classify and score them based on the custom-trained classifier.

Abstract: An article and method for using the same is disclosed. The article is worn on a user's head and secures a mask to the user's face without requiring loops associated with the mask to be worn over the back of the ears of the user, thereby eliminating strain and discomfort on the user's ears.

Abstract: An example system for automated aquatic insect rearing includes a frame; at least one trough having a drain, the trough supported by the frame; a drain valve coupled to the drain; a lid coupleable to the at least one trough to cover the trough, the lid defining at least one opening; a fluid supply tube connectable to a fluid supply, the fluid supply tube routed to provide fluid to the at least one trough; a fill valve coupled to the fluid supply tube, the fill valve positioned and configured to regulate a flow of fluid into the at least one trough; a fill pump coupled to the at least one fluid supply tube and coupleable to the fluid supply to pump fluid from the fluid supply through the at least one supply tube; at least one feeding mechanism to dispense food into the at least one trough; and at least one fluid level sensor positioned to detect a fluid level within the at least one trough.

Abstract: A device including a fluid-tight container, wherein the fluid-tight container includes a base having a first portion and a second portion; at least one wall enclosing the base and coupled to the base to form a fluid-tight seal; wherein the first portion of the base comprises a first color and defines a recess; and wherein the second portion of the base comprises a second color darker than the first color.

Abstract: Embodiments of a system and method for identifying and prioritizing company prospects by training at least one classifier on client company win/loss metrics. One or more classifiers can be trained on a training database compiled from company win/loss database for a client and firmographic data from a robust business entity database. Once trained, the system can employ Artificial Intelligence powered by the trained classifiers to classify and output customized prospect lists of thousands of profiled and scored companies that the AI has determined are likely targets for specific marketing and sales. The AI can also ingest databases of client targets and classify and score them based on the custom-trained classifier.

Abstract: The present invention provides isolated, engineered multivalent antibody fragments that specifically bind ?V?6 integrin. In particular embodiments, the antibody fragments of the present invention further comprise an imaging agent and/or a therapeutic agent. In some instances, the antibody fragments also include unnatural amino acids and/or inserted cysteine or thiol residues at the C-terminus of the scFv molecules of the fragments. The anti-?V?6 integrin antibody fragments provided herein are particularly useful for imaging a tumor, organ or tissue and for treating an ?V?6 integrin-mediated disease or disorder. Compositions and kits containing the multivalent antibody fragments of the present invention are also described herein.

Abstract: A system and method for deriving a material change attribute over time to predict a future change in at least one predictor, the method comprising: collecting precursor data from at least one data source; processing the precursor data by assessing at least one characteristic of the precursor data; generating at least one material change signal from the processed precursor data; evaluating the material change signal to determine the signal's value in predicting future changes in the predictor and, optionally, reverting to the collection and processing steps above to process additional precursor data; and generating at least one the material change attribute from the evaluated material change signal.

Abstract: A cooler, structure for transporting a cooler and a method for transporting the same are disclosed. The cooler has a cooling region defined by a support wall, a first wall, a second wall, and a sloped interior section, the sloped interior section extending between the first wall and the second wall and sloping away from the support wall. A discharge region is provided and is defined by the first wall, the second wall, the sloped interior section, and a vertical wall, the vertical wall being substantially parallel to the support wall. A frame member is positioned proximate the support wall. The frame member has support legs which extend therefrom in a direction way from the vertical wall. The frame member and support legs support the cooler when the cooler is rotated and positioned on a surface.

Abstract: Embolic protection filters, filter membranes, and methods for making and using the same. An example embolic protection filter may include an elongate shaft having a proximal region and a distal region. A filter frame may be to the distal region. A filter membrane may be attached to the filter frame. The filter membrane may have a plurality of apertures formed therein. The filter membrane may include a polymer having a bulk portion and a surface portion. The surface portion may include a surface modification.

Abstract: A wire may be configured to provide distal isolation from proximal movement, and a filter may be deployed at or near a distal portion of the wire. A filter may be deployed on a spinner tube that is rotatably disposed about a distal portion of the wire. Axial movement of the filter wire may be at least partially absorbed by the spinner tube. A telescoping wire may include a solid proximal wire section, a solid distal wire section and a joining section that is disposed between the solid proximal wire section and the solid distal wire section. The joining section may translate rotational movement between the distal and proximal sections.

Abstract: A method for making a solid oxide fuel cell component includes depositing a cathode material directly onto a metallic interconnect. The interconnect may comprise stainless steel or another suitable metal. The cathode material may comprise a ceramic. Examples of cathode materials are yttria-stabilized zirconia (YSZ) and mixtures of YSZ with other ceramics such as lanthanum strontium manganate. The cathode material may be deposited by plasma spraying. A pore former may be plasma sprayed together with the cathode material to provide a porous cathode. Electrolyte and anode materials may be deposited on the cathode material also by plasma spraying. Plasma conditions may be selected to provide a dense electrolyte layer.

Abstract: A wire may be configured to provide distal isolation from proximal movement, and a filter may be deployed at or near a distal portion of the wire. A filter may be deployed on a spinner tube that is rotatably disposed about a distal portion of the wire. Axial movement of the filter wire may be at least partially absorbed by the spinner tube. A telescoping wire may include a solid proximal wire section, a solid distal wire section and a joining section that is disposed between the solid proximal wire section and the solid distal wire section. The joining section may translate rotational movement between the distal and proximal sections.

Abstract: Embolic protection filtering devices and methods for making and using the same. An example filtering device includes a filter wire and a filter coupled to the filter wire. The filter can include a filter loop and a filter membrane coupled to the filter loop. A plurality of tubular members may be coupled to the filter membrane.

Abstract: Embolic protection filtering devices and methods for making and using the same. An example filtering device includes a filter wire, a filter slidable over the filter wire, and a filter membrane coupled to the filter frame. The filter wire includes a plurality of stops. The filter includes a proximal tubular member, a distal tubular member, and a connecting tubular member extending between the proximal tubular member and the distal tubular member.