Abstract: An apparatus and methods are provided for a dried blood sample collection device that facilitates self-testing by untrained personnel such as patients taking samples at home. The blood sample collection device comprises an actuator disposed through a distal barrel and a proximal barrel of the pen. Multiple frits for receiving blood samples are disposed within a distal end of the actuator. The frits are retained in a retracted position within the distal barrel by a biasing mechanism. A push button facilitates compressing the biasing mechanism and extending the frits through a distal opening of the distal barrel. The frits are configured to intake blood samples and store the samples in a dried state. A suitable desiccant may be used to cause the dried state. The actuator is configured to be removed from the blood sample collection device to enable retrieving dried blood samples from the distal end of the actuator.