Abstract: There are provided methods for the real-time radiation-assisted fabrication of freeform three-dimensional structures. For example, one of these methods comprise depositing on a substrate, by means of nozzle, a filament comprising a curable polymer, while exposing the filament to a radiation so as to cure the curable polymer, and while moving the substrate and the nozzle, with respect to one another, according to the x-axis, y-axis, and z-axis or at least two of these axes. Such a method permits to obtain a freeform three-dimensional structure having at least one point of contact with the substrate.