Patents by Inventor Brain A. Zabel

Brain A. Zabel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of inhibiting GPR-9-6 function
    Patent number: 6936248
    Abstract: The invention relates to an antibody or antigen-binding fragment thereof which binds to the CC chemokine receptor GPR-9-6 and blocks the binding of a ligand (e.g., TECK) to the receptor. The invention also relates to a method of identifying agents (molecules, compounds) which can bind to GPR-9-6 and inhibit the binding of a ligand (e.g., TECK) and/or modulate a function of GPR-9-6. The invention further relates to a method of modulating a function of GPR-9-6, and to the use of the antibodies, antigen-binding fragments and agents identified by the method of the invention in research, therapeutic, prophylactic and diagnostic methods.
    Type: Grant
    Filed: March 10, 2000
    Date of Patent: August 30, 2005
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: David P. Andrew, Brain A. Zabel, Paul D. Ponath