Patents by Inventor Brandon A. Carter-Cooper

Brandon A. Carter-Cooper has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aziridinyl and amino dimeric naphthoquinone compounds and use for acute myeloid leukemia
    Patent number: 11459313
    Abstract: The invention relates to new amino dimeric naphthoquinone compounds with antileukemic activity. Compounds of the invention demonstrated increased aqueous solubility compared to previously available dimeric naphthoquinones and potent nanomolar inhibition of cell survival in AML cells. Preferred compounds contained an aziridine or a secondary amino alcohol pharmacophore.
    Type: Grant
    Filed: October 5, 2017
    Date of Patent: October 4, 2022
    Assignees: UNIVERSITY OF MARYLAND, BALTIMORE, MCDANIEL COLLEGE
    Inventors: Ashkan Emadi, Rena G. Lapidus, Brandon A. Carter-Cooper, Steven Fletcher, Dana Ferraris, Edward A. Sausville
  • AZIRIDINYL AND AMINO DIMERIC NAPHTHOQUINONE COMPOUNDS AND USE FOR ACUTE MYELOID LEUKEMIA
    Publication number: 20200283417
    Abstract: The invention relates to new amino dimeric naphthoquinone compounds with antileukemic activity. Compounds of the invention demonstrated increased aqueous solubility compared to previously available dimeric naphthoquinones and potent nanomolar inhibition of cell survival in AML cells. Preferred compounds contained an aziridine or a secondary amino alcohol pharmacophore.
    Type: Application
    Filed: October 5, 2017
    Publication date: September 10, 2020
    Inventors: Ashkan Emadi, Rena G. Lapidus, Brandon A. Carter-Cooper, Steven Fletcher, Dana Ferraris, Edward A. Sausville
  • Compositions and methods for the treatment of cancers
    Patent number: 9381215
    Abstract: The present invention provides a formulation comprising dichloroacetate and arsenic trioxide. The present invention also provides a method of treating cancer by administering a therapeutically effective amount of dichloroacetate and arsenic trioxide.
    Type: Grant
    Filed: February 17, 2015
    Date of Patent: July 5, 2016
    Assignee: UNIVERSITY OF MARYLAND, BALTIMORE
    Inventors: Ashkan Emadi, Rena Lapidus, Mariola Sadowska, Brandon Carter-Cooper, Edward Sausville
  • Compositions and Methods for the Treatment of Cancers
    Publication number: 20150231176
    Abstract: The present invention provides a formulation comprising dichloroacetate and arsenic trioxide. The present invention also provides a method of treating cancer by administering a therapeutically effective amount of dichloroacetate and arsenic trioxide.
    Type: Application
    Filed: February 17, 2015
    Publication date: August 20, 2015
    Applicant: UNIVERSITY OF MARYLAND, BALTIMORE
    Inventors: Ashkan Emadi, Rena Lapidus, Mariola Sadowska, Brandon Carter-Cooper, Edward Sausville