Abstract: This invention relates to compositions, methods, strategies, and treatment modalities related to the epigenetic modification of hepatitis B virus (HBV) genes.

Abstract: A handheld filter press includes a pump, a water chamber, and a portafilter basket. The pump includes a pump housing that defines a pump chamber configured to pressurize air, and defines a pump outlet for exhausting pressurized air. The pump includes an outlet valve fluidly connected with the pump outlet. The outlet valve allows air to exit the pump chamber and prevents air from entering the pump chamber through the pump outlet. The water chamber is fluidly connected with the pump chamber through the outlet valve for receiving pressurized air from the pump chamber. The water chamber defines a water chamber outlet for exhausting pressurized air and water from the water chamber. The portafilter basket is fluidly connected with the water chamber for receiving pressurized water from the water chamber through the water chamber outlet. The portafilter basket is configured to store grounds, and to express a brewed beverage.

Abstract: Anatomically contoured ambidextrous compression glove particularly for the hand, form fitting to the tissue to ensure targeted delivery of therapeutic treatment to specific tissue, and yet remain stably affixed without pinching or binding, and allow for motion and use of the tissue while delivering targeted therapeutic treatment.

Abstract: A therapeutic device includes flexible vibrating module with flexible radiating arms outwardly projecting around the module, with each arm having an associated coin motor which can optionally be operated at high frequency or low frequency or pulsing frequency. In addition to the vibratory elements of the device, a selective thermal element is included to provide heating and/or cooling for additional therapy. The heat, cooling, and/or vibrations can be used together or alone to provide therapeutic benefits to various body locations of a user. The device can be used with a wrap to hold the device in place for use.

Abstract: A flexible compressive orthopedic knee sleeve of stretchable fabric having an exterior surface webbing material at least partially covering the sleeve to provide targeted compressive force similar to athletic taping and to also provide kinetic retention.

Abstract: Anatomically contoured ambidextrous compression glove particularly for the hand, form fitting to the tissue to ensure targeted delivery of therapeutic treatment to specific tissue, and yet remain stably affixed without pinching or binding, and allow for motion and use of the tissue while delivering targeted therapeutic treatment.