Abstract: A system and method performing a medical imaging process includes arranging a subject to receive an exogenously administered free radical probe, performing an Overhauser-enhanced MRI (OMRI) imaging process to acquire data from the subject, and reconstructing the data to generate a report indicating a spatial distribution of free radicals in the subject.

Abstract: A system and method for performing a medical imaging process includes arranging a subject to be imaged in a magnetic resonance imaging (MRI) system and performing, using the MRI system, a magnetic resonance (MR) imaging pulse sequence. While performing the MR pulse sequence, electron paramagnetic resonance (EPR) pulses are performed at least during the application of the phase encoding gradients or only during the MR pulse sequence. Data is acquired that corresponds to signals from the subject excited by the MR pulse sequence and the EPR pulses. At least one image of the subject is reconstructed from the data.

Abstract: A system and method for generating a report about a subject positioned within a bore of a magnetic resonance imaging (MRI) system includes controlling the MRI system to perform a magnetic resonance fingerprinting (MRF) pulse sequence that at least partially samples k-space using either fractional Cartesian or non-Cartesian sequential sampling pattern to acquire imaging data from the subject. The process also includes estimating quantitative parameters by comparing the acquired imaging data with at least one database comprising a plurality signal templates.