Publication number: 20180099019
Abstract: The present disclosure provides Diels-Alder adducts of chalcone and prenylphenyl moieties capable of modulating the activity of cannabinoid receptors, and to oligomers of flavan-3-ol capable of modulating fat absorption and storage. Such Diels-Alder adducts of chalcone and prenylphenyl moieties or oligomers of flavan-3-ol can optionally be used in combination with other weight management agents, such as anorectic agents, a lipase inhibitors, other cannabinoid receptor modulators, psychotropic agents, insulin sensitizers, stimulants, or satiety agents, as well as to methods of use thereof such as treating or preventing weight gain or obesity, promoting weight loss, appetite suppression, modifying satiety, or the like.
Type:
Application
Filed:
December 11, 2017
Publication date:
April 12, 2018
Applicants:
Unigen, Inc., Unigen, Inc.
Inventors:
Lidia Alfaro Brownell, Byong-II Choi, Brandon Corneliusen, Mei-Feng Hong, Eu-Jin Hyun, QI Jia, Ping Jiao, Hyun-Jin Kim, Mi-Ran Kim, Tae-Woo Kim, Bo-Su Lee, Young-Chul Lee, Jeong-Bum Nam, Mesfin Yimam, Ji-Hye Hwang, Mi-Sun Oh
Patent number: 9844576
Abstract: The present disclosure provides Diels-Alder adducts of chalcone and prenylphenyl moieties capable of modulating the activity of cannabinoid receptors, and to oligomers of flavan-3-ol capable of modulating fat absorption and storage. Such Diels-Alder adducts of chalcone and prenylphenyl moieties or oligomers of flavan-3-ol can optionally be used in combination with other weight management agents, such as anorectic agents, a lipase inhibitors, other cannabinoid receptor modulators, psychotropic agents, insulin sensitizers, stimulants, or satiety agents, as well as to methods of use thereof such as treating or preventing weight gain or obesity, promoting weight loss, appetite suppression, modifying satiety, or the like.
Type:
Grant
Filed:
May 29, 2013
Date of Patent:
December 19, 2017
Assignees:
Unigen, Inc., Unigen, Inc.
Inventors:
Lidia Alfaro Brownell, Byong-Il Choi, Brandon Corneliusen, Mei-Feng Hong, Eu-Jin Hyun, Qi Jia, Ping Jiao, Hyun-Jin Kim, Mi-Ran Kim, Tae-Woo Kim, Bo-Su Lee, Young-Chul Lee, Jeong-Bum Nam, Mesfin Yimam, Ji-Hye Hwang, Mi-Sun Oh
Publication number: 20140004215
Abstract: The present disclosure provides Diels-Alder adducts of chalcone and prenylphenyl moieties capable of modulating the activity of cannabinoid receptors, and to oligomers of flavan-3-ol capable of modulating fat absorption and storage. Such Diels-Alder adducts of chalcone and prenylphenyl moieties or oligomers of flavan-3-ol can optionally be used in combination with other weight management agents, such as anorectic agents, a lipase inhibitors, other cannabinoid receptor modulators, psychotropic agents, insulin sensitizers, stimulants, or satiety agents, as well as to methods of use thereof such as treating or preventing weight gain or obesity, promoting weight loss, appetite suppression, modifying satiety, or the like.
Type:
Application
Filed:
May 29, 2013
Publication date:
January 2, 2014
Applicants:
Unigen, Inc., UNIGEN, INC.
Inventors:
Lidia Alfaro BROWNELL, Byong-Il CHOI, Brandon CORNELIUSEN, Mei-Feng HONG, Eu-Jin HYUN, Qi JIA, Ping JIAO, Hyun-Jin KIM, Mi-Ran KIM, Tae-Woo KIM, Bo-Su LEE, Young-Chul LEE, Jeong-Bum NAM, Mesfin YIMAN, Ji-Hye Hwang, Mi-Sun OH