Patents by Inventor Brandon J. Downey

Brandon J. Downey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210047606
    Abstract: The present disclosure is directed to systems and methods for sampling and/or controlling the productivity of a bioreactor. The system and methods can include a vessel capable of providing an environment suitable for containing whole broth that can produce the bioproduct, wherein the whole broth contains media and at least one undissolved species, an automated sampling system, a first analytical instrument, and a control system.
    Type: Application
    Filed: October 30, 2020
    Publication date: February 18, 2021
    Applicant: Bend Research, Inc.
    Inventors: Roderick J. Ray, Adam S. Carroll, Brandon J. Downey, Lisa J. Graham
  • Patent number: 10836991
    Abstract: The present disclosure is directed to systems and methods for sampling and/or controlling the productivity of a bioreactor. The system and methods can include a vessel capable of providing an environment suitable for containing whole broth that can produce the bioproduct, wherein the whole broth contains media and at least one undissolved species, an automated sampling system, a first analytical instrument, and a control system.
    Type: Grant
    Filed: August 30, 2019
    Date of Patent: November 17, 2020
    Assignee: Bend Research, Inc.
    Inventors: Roderick J. Ray, Adam S. Carroll, Brandon J. Downey, Lisa J. Graham
  • Publication number: 20200291439
    Abstract: The instant disclosure provides a process for making pullulan.
    Type: Application
    Filed: April 9, 2018
    Publication date: September 17, 2020
    Applicant: Capsugel Belgium NV
    Inventors: Jeffrey F. BREIT, Brandon J. DOWNEY, Justin BELLER
  • Publication number: 20200182545
    Abstract: Spray drying method and systems are disclosed that include one or more single-use components. Single-use spray drying systems can include a drying chamber with an inner surface formed of a polymeric material. The single-use components can be pre-sterilized and sterile packaged to provide improved efficiencies and greater flexibility in spray drying systems.
    Type: Application
    Filed: August 28, 2018
    Publication date: June 11, 2020
    Applicant: Capsugel Belgium NV
    Inventors: Brandon J. Downey, Anthony Quach, Dave Hansen, Travis L. Harrer, John Michael Baumann
  • Publication number: 20200017818
    Abstract: The present disclosure is directed to systems and methods for sampling and/or controlling the productivity of a bioreactor. The system and methods can include a vessel capable of providing an environment suitable for containing whole broth that can produce the bioproduct, wherein the whole broth contains media and at least one undissolved species, an automated sampling system, a first analytical instrument, and a control system.
    Type: Application
    Filed: August 30, 2019
    Publication date: January 16, 2020
    Applicant: Bend Research, Inc.
    Inventors: Roderick J. Ray, Adam S. Carroll, Brandon J. Downey, Lisa J. Graham
  • Patent number: 10421939
    Abstract: The present disclosure is directed to systems and methods for sampling and/or controlling the productivity of a bioreactor.
    Type: Grant
    Filed: October 24, 2012
    Date of Patent: September 24, 2019
    Assignee: Bend Research, Inc.
    Inventors: Roderick J. Ray, Adam S. Carroll, Brandon J. Downey, Lisa J. Graham
  • Patent number: 9568449
    Abstract: Methods and apparatus are disclosed for correcting measurements received by applying a frequency-varying signal with a measuring device (e.g., a permittivity probe) to a population of living cells (e.g., contained in a bioreactor) and correcting measurement divergences using data acquired using an alternate analytical method (e.g., trypan blue exclusion). In one example, a method comprises receiving electrical property data for a first population of cells, the data obtained by applying a first frequency-varying signal to the population with a measuring device, receiving biological property data obtained using an alternate analytical technique, generating at least one value representative of the frequency dependence of the electrical property data, and determining a relationship between the biological property data and the representative value. In some examples, measurements of apoptosis are predicted using the electrical property data.
    Type: Grant
    Filed: January 4, 2013
    Date of Patent: February 14, 2017
    Assignee: Bend Research, Inc.
    Inventors: Brandon J. Downey, Jeffery F. Breit, Lisa Graham, Adam S. Carroll
  • Publication number: 20150019140
    Abstract: Methods and apparatus are disclosed for correcting measurements received by applying a frequency-varying signal with a measuring device (e.g., a permittivity probe) to a population of living cells (e.g., contained in a bioreactor) and correcting measurement divergences using data acquired using an alternate analytical method (e.g., trypan blue exclusion). In one example, a method comprises receiving electrical property data for a first population of cells, the data obtained by applying a first frequency-varying signal to the population with a measuring device, receiving biological property data obtained using an alternate analytical technique, generating at least one value representative of the frequency dependence of the electrical property data, and determining a relationship between the biological property data and the representative value. In some examples, measurements of apoptosis are predicted using the electrical property data.
    Type: Application
    Filed: January 4, 2013
    Publication date: January 15, 2015
    Applicant: Bend Research, Inc.
    Inventors: Brandon J. Downey, Jeffery F. Breit, Lisa Graham, Adam S. Carroll
  • Publication number: 20140295532
    Abstract: The present disclosure is directed to systems and methods for sampling and/or controlling the productivity of a bioreactor.
    Type: Application
    Filed: October 24, 2012
    Publication date: October 2, 2014
    Applicant: Bend Research, Inc.
    Inventors: Roderick J. Ray, Adam S. Carroll, Brandon J. Downey, Lisa J. Graham