Abstract: A surgical stapler, or fastening instrument, may generally comprise a layer, such as a tissue thickness compensator, for example, releasably attached to a fastener cartridge and/or anvil by a flowable attachment portion. The flowable attachment portion may be indefinitely flowable. The flowable attachment portion may be flowable from the time that layer is installed to the fastener cartridge to the time in which the layer is implanted to patient tissue. The flowable attachment portion may comprise a pressure sensitive adhesive. The flowable attachment portion may comprise an adhesive laminate comprising a base layer comprising the tissue thickness compensator and an adhesive layer on at least a portion of a surface of the base layer comprising the pressure sensitive adhesive. Articles of manufacture comprising flowable attachment portion and methods of making and using the flowable attachment portion are also described.

Abstract: A fastener cartridge assembly for use with a surgical end effector. The fastener cartridge assembly can comprise a cartridge body having fastener cavities, fasteners removably positioned in the fastener cavities, a layer of material releasably secured relative to the cartridge body, a connector configured to secure the layer of material to the cartridge body at a location distal to at least one fastener cavity, and an actuator. The layer of material can be a tissue thickness compensator. When actuated, the actuator can overcome the connector, and can overcome the connector prior to the removal of the fasteners from the fastener cavities. The actuator can be actuated at a location proximal to at least one fastener cavity, and can extend distally past at least one fastener cavity toward the connector.

Abstract: A fastener cartridge assembly for use with a surgical end effector. The fastener cartridge assembly can comprise a cartridge body having fastener cavities, fasteners removably positioned in the fastener cavities, a layer of material releasably secured relative to the cartridge body, a connector configured to secure the layer of material to the cartridge body at a location distal to at least one fastener cavity, and an actuator. The layer of material can be a tissue thickness compensator. When actuated, the actuator can overcome the connector, and can overcome the connector prior to the removal of the fasteners from the fastener cavities. The actuator can be actuated at a location proximal to at least one fastener cavity, and can extend distally past at least one fastener cavity toward the connector.

Abstract: A fastener cartridge assembly for use with a surgical end effector. The fastener cartridge assembly can comprise a cartridge body having fastener cavities, fasteners removably positioned in the fastener cavities, a layer of material releasably secured relative to the cartridge body, a connector configured to secure the layer of material to the cartridge body at a location distal to at least one fastener cavity, and an actuator. The layer of material can be a tissue thickness compensator. When actuated, the actuator can overcome the connector, and can overcome the connector prior to the removal of the fasteners from the fastener cavities. The actuator can be actuated at a location proximal to at least one fastener cavity, and can extend distally past at least one fastener cavity toward the connector.

Abstract: A fastener cartridge can comprise, one, a cartridge body configured to at least partially store a plurality of fasteners therein and, two, a layer of material attached to the cartridge body by a retention member. The retention member can be deactivated to release the layer from the cartridge body when a firing member is moved through the cartridge body to eject the fasteners from the cartridge body. The retention member can be deactivated at the beginning, the end, and/or at any suitable time during a firing stroke of the firing member. Certain fastener cartridges can comprise a plurality of retention members configured to releasably hold the layer to the cartridge body. In certain circumstances, the retention members can be sequentially released in order to progressively release the layer.

Abstract: A fastener cartridge assembly. The fastener cartridge assembly can comprise a cartridge body, a tissue thickness compensator releasably secured relative to the cartridge body, and a fastener removably positioned in a staple cavity of the cartridge body. The tissue thickness compensator can comprise a first clearance aperture extending along a first predefined trajectory and a second clearance aperture extending along a second predefined trajectory. The fastener can comprise a first leg aligned with the first clearance aperture and moveable along the first predefined trajectory, a second leg aligned with the second clearance aperture and moveable along the second predefined trajectory. The first and second predefined trajectories can be parallel.

Abstract: A fastener cartridge can comprise a cartridge body and a layer, such as a tissue thickness compensator, for example, releasably attached to the cartridge body. The tissue thickness compensator can comprise a compressible first portion and a second support portion. The second portion can be rigid and can support the first portion when mounted thereto. The properties of the first portion and/or the second portion can be selected so as to prevent the premature deflection and release from the cartridge body. The fastener cartridge can further comprise one or more attachment portions configured to releasably hold the tissue thickness compensator to the cartridge body. The attachment portions can be configured to permit a firing member to pass therethrough. In some circumstances, the tissue thickness compensator can be configured to hold the firing member in an unfired position until a sufficient firing force has been applied to the firing member.

Abstract: A fastener cartridge assembly. The fastener cartridge assembly can comprise a cartridge body, a tissue thickness compensator releasably secured relative to the cartridge body, and a fastener removably positioned in a staple cavity of the cartridge body. The tissue thickness compensator can comprise a first clearance aperture extending along a first predefined trajectory and a second clearance aperture extending along a second predefined trajectory. The fastener can comprise a first leg aligned with the first clearance aperture and moveable along the first predefined trajectory, a second leg aligned with the second clearance aperture and moveable along the second predefined trajectory. The first and second predefined trajectories can be parallel.

Abstract: An implantable restriction device includes a belt and a balloon secured to the belt for engagement with tissue when the implantable restriction device is positioned about an organ. A protective member is associated with the balloon for positioning between the balloon and a tissue surface defining a band tissue interface.