Abstract: An air sanitation and purification photocatalytic panel includes a frame that has a photocatalytic scrim positioned within the frame and a plurality of UV light sources positioned within the frame proximate to the photocatalytic scrim. The frame is made of a metal and/or alloy. The photocatalytic scrim is a pleated structure. Each of the plurality of UV light sources are oriented towards the photocatalytic scrim. The photocatalytic scrim includes a substrate a photocatalytic coating adhered to the substrate. The frame and photocatalytic scrim are oriented parallel to each other. The UV light sources illuminate the photocatalytic coating and initiate a photocatalytic reaction therein. During operation, the panel is positioned perpendicular to the airstream such that the airstream is forced through the substrate.