Patents by Inventor Brandon Parkhurst

Brandon Parkhurst has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ketone linked benzothiazole inhibitors of endothelial lipase
    Patent number: 9169240
    Abstract: The present invention provides compounds of Formula (I): as defined in the specification and compositions comprising any of such novel compounds. These compounds are endothelial lipase inhibitors which may be used as medicament.
    Type: Grant
    Filed: September 5, 2013
    Date of Patent: October 27, 2015
    Assignee: Bristol-Myers Squibb Company
    Inventors: George O. Tora, Heather Finlay, Carol Hui Hu, Ji Jiang, James A. Johnson, Soong-Hoon Kim, John Lloyd, Brandon Parkhurst, Zulan Pi, Jennifer X. Qiao, Tammy C. Wang
  • KETONE LINKED BENZOTHIAZOLE INHIBITORS OF ENDOTHELIAL LIPASE
    Publication number: 20150239879
    Abstract: The present invention provides compounds of Formula (I): as defined in the specification and compositions comprising any of such novel compounds. These compounds are endothelial lipase inhibitors which may be used as medicament.
    Type: Application
    Filed: September 5, 2013
    Publication date: August 27, 2015
    Inventors: George O. Tora, Heather Finlay, Carol Hui Hu, Ji Jiang, James A. Johnson, Soong-Hoon Kim, John Lloyd, Brandon Parkhurst, Zulan Pi, Jennifer X. Qiao, Tammy C. Wang
  • Amide, urea or sulfone amide linked benzothiazole inhibitors of endothelial lipase
    Patent number: 8987314
    Abstract: The present invention provides compounds of Formula (I): as defined in the specification and compositions comprising any of such novel compounds. These compounds are endothelial lipase inhibitors which may be used as medicaments.
    Type: Grant
    Filed: July 18, 2013
    Date of Patent: March 24, 2015
    Assignee: Bristol-Myers Squibb Company
    Inventors: Heather Finlay, Ji Jiang, Soong-Hoon Kim, Brandon Parkhurst, Jennifer X. Qiao, Tammy C. Wang, Zulan Pi, George O. Tora, John Lloyd, James A. Johnson
  • AMIDE, UREA OR SULFONE AMIDE LINKED BENZOTHIAZOLE INHIBITORS OF ENDOTHELIAL LIPASE
    Publication number: 20140045811
    Abstract: The present invention provides compounds of Formula (I): as defined in the specification and compositions comprising any of such novel compounds. These compounds are endothelial lipase inhibitors which may be used as medicaments.
    Type: Application
    Filed: July 18, 2013
    Publication date: February 13, 2014
    Inventors: Heather Finlay, Ji Jiang, Soong-Hoon Kim, Brandon Parkhurst, Jennifer X. Qiao, Tammy C. Wang, Zulan Pi, George O. Tora, John Lloyd, James A. Johnson
  • Macrocyclic factor VIIa inhibitors useful as anticoagulants
    Patent number: 8420830
    Abstract: The present invention relates generally to novel macrocycles of Formula (I): or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein the variables A, B, C, D, L, M, W, Z1, Z2, Z3, Z4, R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 are as defined herein. These compounds are selective inhibitors of factor VIIa which can be used as medicaments.
    Type: Grant
    Filed: December 19, 2007
    Date of Patent: April 16, 2013
    Assignee: Bristol-Myers Squibb Company
    Inventors: Nicholas Ronald Wurtz, Eldon Scott Priestley, Daniel L. Cheney, Peter W. Glunz, Xiaojun Zhang, Brandon Parkhurst, Vladimir Ladziata, Luciano Mueller
  • Bicyclic lactam factor VIIa inhibitors useful as anticoagulants
    Patent number: 8039506
    Abstract: The present invention provides novel bicyclic lactams derivatives, and analogues thereof, of Formula (I): or a stereoisomer, tautomer, pharmaceutically acceptable salt, solvate, or prodrug thereof, wherein the variables A, B, C, W, Y, Z1, Z2, Z3, Z4, R8, and R9 are as defined herein. These compounds are selective inhibitors of factor VIIa which can be used as medicaments.
    Type: Grant
    Filed: December 17, 2007
    Date of Patent: October 18, 2011
    Assignee: Bristol-Myers Squibb Company
    Inventors: Nicholas Ronald Wurtz, Eldon Scott Priestley, Daniel L. Cheney, Xiaojun Zhang, Brandon Parkhurst, Vladimir Ladziata
  • MACROCYCLIC FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS
    Publication number: 20100113488
    Abstract: The present invention relates generally to novel macrocycles of Formula (I): or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein the variables A, B, C, D, L, M, W, Z1, Z2, Z3, Z4, R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 are as defined herein. These compounds are selective inhibitors of factor VIIa which can be used as medicaments.
    Type: Application
    Filed: December 19, 2007
    Publication date: May 6, 2010
    Inventors: Nicholas Ronald Wurtz, Eldon Scott Priestley, Daniel L. Cheney, Peter W. Glunz, Xiaojun Zhang, Brandon Parkhurst, Vladimir Ladziata, Luciano Mueller
  • BICYCLIC LACTAM FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS
    Publication number: 20100041664
    Abstract: The present invention provides novel bicyclic lactams derivatives, and analogues thereof, of Formula (I): or a stereoisomer, tautomer, pharmaceutically acceptable salt, solvate, or prodrug thereof, wherein the variables A, B, C, W, Y, Z1, Z2, Z3, Z4, R8, and R9 are as defined herein. These compounds are selective inhibitors of factor VIIa which can be used as medicaments.
    Type: Application
    Filed: December 17, 2007
    Publication date: February 18, 2010
    Inventors: Nicholas Ronald Wurtz, Eldon Scott Priestley, Daniel L. Cheney, Xiaojun Zhang, Brandon Parkhurst, Vladimir Ladziata
  • Novel pyrazolopyridine derivatives as pharmaceutical agents
    Publication number: 20050222197
    Abstract: Novel pyrazolopyridine derivative compounds are disclosed and their use as pharmaceutical agents, in particular their use as TGF-beta signal transduction inhibitors useful in the treatment of cancer and other disease states influenced by TGF beta.
    Type: Application
    Filed: September 16, 2003
    Publication date: October 6, 2005
    Inventors: Douglas Beight, Rosanne Bonjouklian, Junkai Liao, William McMillen, Brandon Parkhurst, Jason Sawyer, Jonathan Yingling, Jeremy York