Patents by Inventor Branko Mitasev

Branko Mitasev has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • APICOMPLEXAN PARASITE INHIBITION
    Publication number: 20230279018
    Abstract: The invention provides agents that inhibit L-Phe in cytoplasmic phenylalanine tRNA-synthetase (cFRS), methods for identifying them, compositions comprising such agents, and therapeutic methods of using such agents.
    Type: Application
    Filed: March 22, 2023
    Publication date: September 7, 2023
    Applicants: The Broad Institute, Inc., President and Fellows of Harvard College, Eisai R&D Management Co., LTD.
    Inventors: Eamon COMER, Bruno MELILLO, Francis G. FANG, Branko MITASEV
  • METHOD FOR SYNTHESIS OF DIAZABICYCLO[6.2.0]DECANE RELATED COMPOUNDS
    Publication number: 20220112207
    Abstract: A method for the synthesis of diazabicyclo[6.2.0]decane compounds is provided. The synthesis proceeds by stereoselective synthesis of a chiral lactone followed by azetidine formation via a series of chemoselective reactions. Bicyclization results with the formation of diazobicyclo[6.2.0]decane related compounds.
    Type: Application
    Filed: January 9, 2020
    Publication date: April 14, 2022
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Francis G. FANG, Branko MITASEV, Jiong YANG
  • Methods and compounds useful in the synthesis of fused aminodihydrothiazine derivatives
    Patent number: 8962858
    Abstract: Provided are compounds and methods useful for the preparation of compounds useful as inhibitors of beta-site amyloid precursor protein (APP)-cleaving enzyme.
    Type: Grant
    Filed: June 26, 2014
    Date of Patent: February 24, 2015
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Branko Mitasev, Dae-Shik Kim, Huiming Zhang, Christopher N. Farthing
  • METHODS AND COMPOUNDS USEFUL IN THE SYNTHESIS OF FUSED AMINODIHYDROTHIAZINE DERIVATIVES
    Publication number: 20140309429
    Abstract: Provided are compounds and methods useful for the preparation of compounds useful as inhibitors of beta-site amyloid precursor protein (APP)-cleaving enzyme.
    Type: Application
    Filed: June 26, 2014
    Publication date: October 16, 2014
    Inventors: Branko Mitasev, Dae-Shik Kim, Huiming Zhang, Christopher N. Farthing
  • Methods and compounds useful in the synthesis of fused aminodihydrothiazine derivatives
    Patent number: 8802871
    Abstract: Provided are compounds and methods useful for the preparation of compounds useful as inhibitors of beta-site amyloid precursor protein (APP)-cleaving enzyme.
    Type: Grant
    Filed: March 12, 2013
    Date of Patent: August 12, 2014
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Branko Mitasev, Dae-Shik Kim, Huiming Zhang, Matthew J. Schnaderbeck, Christopher N. Farthing
  • Methods and compounds useful in the synthesis of fused aminodihydrothiazine derivatives
    Patent number: 8426584
    Abstract: Provided are compounds and methods useful for the preparation of compounds useful as inhibitors of beta-site amyloid precursor protein (APP)-cleaving enzyme.
    Type: Grant
    Filed: January 20, 2012
    Date of Patent: April 23, 2013
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Branko Mitasev, Dae-Shik Kim, Kazuhiro Yoshizawa
  • METHODS AND COMPOUNDS USEFUL IN THE SYNTHESIS OF FUSED AMINODIHYDROTHIAZINE DERIVATIVES
    Publication number: 20120190848
    Abstract: Provided are compounds and methods useful for the preparation of compounds useful as inhibitors of beta-site amyloid precursor protein (APP)-cleaving enzyme.
    Type: Application
    Filed: January 20, 2012
    Publication date: July 26, 2012
    Inventors: Branko Mitasev, Dae-Shik Kim, Huiming Zhang, Matthew J. Schnaderbeck, Christopher N. Farthing, Kazuhiro Yoshizawa