Patents by Inventor Branko Zevnik

Branko Zevnik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Automated gene-targeting using non-toxic detectable markers
    Publication number: 20060179502
    Abstract: The invention relates to a method that enables automated identification and isolation of cells harbouring a predetermined genetic modification (homologous recombination) using detectable/sortable markers, e.g. fluorescence markers, to identify homologous DNA modifications. Suitable vectors are also provided.
    Type: Application
    Filed: February 3, 2004
    Publication date: August 10, 2006
    Applicant: ARTEMIS PHARMACEUTICALS GMBH
    Inventors: Gunther Kauselmann, Branko Zevnik, Jost Seibler, Heidrun Kern
  • Inbred embryonic stem-cell derived mice
    Publication number: 20030204862
    Abstract: An improved and reproducible method for the generation of ES mice from inbred ES cells, without the need to generate a chimeric mouse intermediate is provided. The inbred ES cells may be recombinant or genetically modified, resulting in ES mice that are transgenic. The method may also be used for the fast production of ES mice strains homozygous for a defined genetic alteration.
    Type: Application
    Filed: March 4, 2003
    Publication date: October 30, 2003
    Inventors: Ralf Kuehn, Anja Rode, Rudolf Jaenisch, Branko Zevnik
  • RRP sequences and knockout mice and uses thereof
    Publication number: 20030165497
    Abstract: RRP genes are identified as modulators of the p53 or p21 pathway, and thus are therapeutic targets for disorders associated with defective p53 or p21 function. Methods for identifying modulators of p53 or p21, comprising screening for agents that modulate the activity of RRP are provided. Modulating agents identified using the methods of the invention can be used to specifically inhibit growth of tumor cells that overexpress an RRP protein. mRRP1 knockout mice are also provided.
    Type: Application
    Filed: January 23, 2002
    Publication date: September 4, 2003
    Inventors: Mario N. Lioubin, Lori Friedman, Marcia Belvin, Jeffrey S. Larson, Changyou Chen, Stephanie A. Robertson, Wen Shi, Jocelyn Chan, Danxi Li, Helen Francis-Lang, Gregory D. Plowman, Roel P. Funke, Michael Schoor, Branko Zevnik, Gunther Kauselmann, Hartmut Tintrup