Patents by Inventor Brantley HERRIN

Brantley HERRIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • VARIANT ACTRIIB PROTEINS AND USES THEREOF
    Publication number: 20230183319
    Abstract: In certain aspects, the present invention provides novel ActRIIB variants (in a homomultimeric or heteromultimeric form), as well as compositions and methods for using those variants to treat an indication associated with undesired activity of one or more TGF?-superfamily ligands. The present invention also provides methods of screening compounds that modulate activity of an ActRIIB protein and/or an ActRIIB ligand. The compositions and methods provided herein are useful in treating diseases associated with abnormal activity of an ActRIIB protein and/or an ActRIIB ligand.
    Type: Application
    Filed: February 3, 2021
    Publication date: June 15, 2023
    Inventors: Ravindra Kumar, Roselyne Castonguay, Brantley Herrin, Rose Maria Silva Garcia Grenha
  • VARIABLE LYMPHOCYTE RECEPTORS THAT TARGET THE BRAIN EXTRACELLULAR MATRIX AND METHODS OF USE
    Publication number: 20220041659
    Abstract: The present disclosure provides isolated polypeptides comprising variable lymphocyte receptors that specifically bind the brain extracellular matrix, compositions, and methods of use. Methods of using the variable lymphocyte receptors for the detection and treatment of disease or injury, specifically, for example, cancers including glioblastoma are provided.
    Type: Application
    Filed: December 19, 2019
    Publication date: February 10, 2022
    Inventors: Eric V. SHUSTA, Benjamin UMLAUF, Brantley HERRIN, Paul CLARK, John KUO