Abstract: New insecticidal combinations, compositions, and methods of using the same are provided. The present invention is directed to combinations of Cysteine Rich Insecticidal Peptides (CRIPS), and Insecticidal Agents (IAs). The present invention also describes the use of said combinations and compositions for the control of insects. Here, we describe the following: genes encoding CRIPs; compositions and combinations comprising CRIPs and IAs; and methods using the same that are useful for the control of pests.

Abstract: New insecticidal peptides, polypeptides, proteins, and nucleotides; their expression in culture and plants; methods of producing the peptides, polypeptides, proteins, and nucleotides; new processes; new production techniques; new formulations; and new organisms, are disclosed. The present disclosure is also related to a novel type of peptide named Dc1a-Variant Polypeptides (DVPs) that are a non-naturally occurring, modified-form of the peptide, Mu-diguetoxin-Dc1a, isolated from the American Desert Spider (Diguetia canities). Here we describe: genes encoding DVPs; various formulations and combinations of both genes and peptides; and methods for using the same that are useful for the control of insects. Further, the present invention relates to novel, recombinant cysteine rich proteins (CRPs) with a cystine knot (CK) architecture, created by removing one or more disulfide bonds from a polypeptide having four or more disulfide bonds.

Abstract: New insecticidal proteins, nucleotides, peptides, and their expression in plants. Methods of producing new nucleotides and new peptides, new processes, new production techniques, new formulations, and new organisms. The present disclosure is also related to and describes novel peptides called TVPs, which are non-natural peptide variations based upon the U1-agatoxin-Ta1b toxin derived from the Hobo spider. Here, we describe: genes encoding TVPs; formulations and combinations comprising TVP genes and/or peptides; and methods using the same that are useful for the control of pests.