Patents by Inventor Brenda S. Morse

Brenda S. Morse has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Micronized placental tissue compositions and methods of making and using the same
    Patent number: 11931384
    Abstract: Described herein are compositions composed of micronized placental components and pharmaceutical compositions thereof. The compositions have numerous medical applications. Methods for making and using the micronized compositions are also described herein.
    Type: Grant
    Filed: December 16, 2021
    Date of Patent: March 19, 2024
    Assignee: MiMedx Group, Inc.
    Inventors: Brenda S. Morse, Somaly Sith, Randall Spencer, Steven Ray, John Daniel, Robert Tofe
  • Laminated tissue grafts composed of Wharton's jelly and methods of making and using the same
    Patent number: 11602549
    Abstract: Described herein are tissue grafts derived from the placenta with improved physical and biological properties. In one aspect, the tissue graft includes a first membrane comprising Wharton's jelly laminated with amnion, chorion, or a combination thereof. The presence of Wharton's jelly in the grafts enhances the performance of allograft amniotic-derived, caderivic allograft, xenograft, or alloplast soft tissue substitutes.
    Type: Grant
    Filed: May 23, 2019
    Date of Patent: March 14, 2023
    Assignee: MiMedx Group, Inc.
    Inventors: Brenda S. Morse, Somaly Sith, Randall Spencer, John Daniel, Robert Tofe
  • MICRONIZED PLACENTAL TISSUE COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20220125855
    Abstract: Described herein are compositions composed of micronized placental components and pharmaceutical compositions thereof. The compositions have numerous medical applications. Methods for making and using the micronized compositions are also described herein.
    Type: Application
    Filed: January 10, 2022
    Publication date: April 28, 2022
    Inventors: Brenda S. Morse, Somaly Sith, Randall Spencer, Steven Ray, John Daniel, Robert Tofe
  • MICRONIZED PLACENTAL TISSUE COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20220105138
    Abstract: Described herein are compositions composed of micronized placental components and pharmaceutical compositions thereof. The compositions have numerous medical applications. Methods for making and using the micronized compositions are also described herein.
    Type: Application
    Filed: December 16, 2021
    Publication date: April 7, 2022
    Applicant: MiMedx Group, Inc.
    Inventors: Brenda S. Morse, Somaly Sith, Randall Spencer, Steven Ray, John Daniel, Robert Tofe
  • Micronized placental tissue compositions and methods of making and using the same
    Patent number: 11235007
    Abstract: Described herein are compositions composed of micronized placental components and pharmaceutical compositions thereof. The compositions have numerous medical applications. Methods for making and using the micronized compositions are also described herein.
    Type: Grant
    Filed: October 18, 2018
    Date of Patent: February 1, 2022
    Assignee: MiMedx Group, Inc.
    Inventors: Brenda S. Morse, Somaly Sith, Randall Spencer, Steven Ray, John Daniel, Robert Tofe
  • Micronized placental tissue compositions and methods of making and using the same
    Patent number: 11219647
    Abstract: Described herein are compositions composed of micronized placental components and pharmaceutical compositions thereof. The compositions have numerous medical applications. Methods for making and using the micronized compositions are also described herein.
    Type: Grant
    Filed: October 18, 2018
    Date of Patent: January 11, 2022
    Assignee: MiMedx Group, Inc.
    Inventors: Brenda S. Morse, Somaly Sith, Randall Spencer, Steven Ray, John Daniel, Robert Tofe
  • Micronized placental tissue compositions and methods of making and using the same
    Patent number: 11103536
    Abstract: Described herein are compositions composed of micronized placental components and pharmaceutical compositions thereof. The compositions have numerous medical applications. Methods for making and using the micronized compositions are also described herein.
    Type: Grant
    Filed: July 24, 2019
    Date of Patent: August 31, 2021
    Assignee: MiMedx Group, Inc.
    Inventors: Brenda S. Morse, Somaly Sith, Randall Spencer, Steven Ray, John Daniel, Robert Tofe
  • Tissue grafts modified with a cross-linking agent and method of making and using the same
    Patent number: 10869951
    Abstract: Described herein are tissue grafts derived from the placenta that possess good adhesion to biological tissues and are useful in would healing applications. In one aspect, the tissue graft includes (1) two or more layers of amnion, wherein at least one layer of amnion is cross-linked, (2) two or more layers of chorion, wherein at least one layer of amnion is cross-linked, or (3) one or more layers of amnion and chorion, wherein at least one layer of amnion and/or chorion is cross-linked. In another aspect, the grafts are composed of amnion and chorion cross-linked with one another. In a further aspect, the grafts have one or more layers sandwiched between the amnion and chorion membranes. The amnion and/or the chorion are treated with a cross-linking agent prior to the formation of the graft. The presence of the cross-linking agent present on the graft also enhances adhesion to the biological tissue of interest. Also described herein are methods for making and using the tissue grafts.
    Type: Grant
    Filed: January 29, 2019
    Date of Patent: December 22, 2020
    Assignee: MiMedx Group, Inc.
    Inventors: Brenda S. Morse, Somaly Sith, Randall Spencer, John Daniel
  • Tissue grafts modified with a cross-linking agent and method of making and using the same
    Patent number: 10869952
    Abstract: Described herein are tissue grafts derived from the placenta that possess good adhesion to biological tissues and are useful in would healing applications. In one aspect, the tissue graft includes (1) two or more layers of amnion, wherein at least one layer of amnion is cross-linked, (2) two or more layers of chorion, wherein at least one layer of amnion is cross-linked, or (3) one or more layers of amnion and chorion, wherein at least one layer of amnion and/or chorion is cross-linked. In another aspect, the grafts are composed of amnion and chorion cross-linked with one another. In a further aspect, the grafts have one or more layers sandwiched between the amnion and chorion membranes. The amnion and/or the chorion are treated with a cross-linking agent prior to the formation of the graft. The presence of the cross-linking agent present on the graft also enhances adhesion to the biological tissue of interest. Also described herein are methods for making and using the tissue grafts.
    Type: Grant
    Filed: January 29, 2019
    Date of Patent: December 22, 2020
    Assignee: MiMedx Group, Inc.
    Inventors: Brenda S. Morse, Somaly Sith, Randall Spencer, John Daniel
  • MICRONIZED PLACENTAL TISSUE COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20190374584
    Abstract: Described herein are composition composed of micronized placental components and pharmaceutical compositions thereof. The compositions have numerous medical applications. Methods for making and using the micronized compositions are also described herein.
    Type: Application
    Filed: July 24, 2019
    Publication date: December 12, 2019
    Inventors: Brenda S. Morse, Somaly Sith, Randall Spencer, Steven Ray, John Daniel, Robert Tofe
  • LAMINATED TISSUE GRAFTS COMPOSED OF WHARTON'S JELLY AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20190307921
    Abstract: Described herein are tissue grafts derived from the placenta with improved physical and biological properties. In one aspect, the tissue graft includes a first membrane comprising Wharton's jelly laminated with amnion, chorion, or a combination thereof. The presence of Wharton's jelly in the grafts enhances the performance of allograft amniotic-derived, caderivic allograft, xenograft, or alloplast soft tissue substitutes.
    Type: Application
    Filed: May 23, 2019
    Publication date: October 10, 2019
    Applicant: MiMedx Gruop, Inc.
    Inventors: Brenda S. Morse, Somaly Sith, Randall Spencer, John Daniel, Robert Tofe
  • Micronized placental tissue compositions and methods of making and using the same
    Patent number: 10376546
    Abstract: Described herein are compositions composed of micronized placental components and pharmaceutical compositions thereof. The compositions have numerous medical applications. Methods for making and using the micronized compositions are also described herein.
    Type: Grant
    Filed: May 23, 2014
    Date of Patent: August 13, 2019
    Assignee: MiMedx Group, Inc.
    Inventors: Brenda S. Morse, Somaly Sith, Randall Spencer, Steven Ray, John Daniel, Robert Tofe
  • Laminated tissue grafts composed of Wharton's jelly and methods of making and using the same
    Patent number: 10350049
    Abstract: Described herein are tissue grafts derived from the placenta with improved physical and biological properties. In one aspect, the tissue graft includes a first membrane comprising Wharton's jelly laminated with amnion, chorion, or a combination thereof. The presence of Wharton's jelly in the grafts enhances the performance of allograft amniotic-derived, caderivic allograft, xenograft, or alloplast soft tissue substitutes.
    Type: Grant
    Filed: February 13, 2012
    Date of Patent: July 16, 2019
    Assignee: MiMedx Group, Inc.
    Inventors: Brenda S. Morse, Somaly Sith, Randall Spencer, John Daniel, Robert Tofe
  • TISSUE GRAFTS MODIFIED WITH A CROSS-LINKING AGENT AND METHOD OF MAKING AND USING THE SAME
    Publication number: 20190192736
    Abstract: Described herein are tissue grafts derived from the placenta that possess good adhesion to biological tissues and are useful in would healing applications. In one aspect, the tissue graft includes (1) two or more layers of amnion, wherein at least one layer of amnion is cross-linked, (2) two or more layers of chorion, wherein at least one layer of amnion is cross-linked, or (3) one or more layers of amnion and chorion, wherein at least one layer of amnion and/or chorion is cross-linked. In another aspect, the grafts are composed of amnion and chorion cross-linked with one another. In a further aspect, the grafts have one or more layers sandwiched between the amnion and chorion membranes. The amnion and/or the chorion are treated with a cross-linking agent prior to the formation of the graft. The presence of the cross-linking agent present on the graft also enhances adhesion to the biological tissue of interest. Also described herein are methods for making and using the tissue grafts.
    Type: Application
    Filed: January 29, 2019
    Publication date: June 27, 2019
    Applicant: MiMedx Group, Inc.
    Inventors: Brenda S. Morse, Somaly Sith, Randall Spencer, John Daniel
  • TISSUE GRAFTS MODIFIED WITH A CROSS-LINKING AGENT AND METHOD OF MAKING AND USING THE SAME
    Publication number: 20190175789
    Abstract: Described herein are tissue grafts derived from the placenta that possess good adhesion to biological tissues and are useful in would healing applications. In one aspect, the tissue graft includes (1) two or more layers of amnion, wherein at least one layer of amnion is cross-linked, (2) two or more layers of chorion, wherein at least one layer of amnion is cross-linked, or (3) one or more layers of amnion and chorion, wherein at least one layer of amnion and/or chorion is cross-linked. In another aspect, the grafts are composed of amnion and chorion cross-linked with one another. In a further aspect, the grafts have one or more layers sandwiched between the amnion and chorion membranes. The amnion and/or the chorion are treated with a cross-linking agent prior to the formation of the graft. The presence of the cross-linking agent present on the graft also enhances adhesion to the biological tissue of interest. Also described herein are methods for making and using the tissue grafts.
    Type: Application
    Filed: January 29, 2019
    Publication date: June 13, 2019
    Applicant: MiMedx Group, lnc.
    Inventors: Brenda S. Morse, Somaly Sith, Randall Spencer, John Daniel
  • MICRONIZED PLACENTAL TISSUE COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20190083548
    Abstract: Described herein are compositions composed of micronized placental components and pharmaceutical compositions thereof. The compositions have numerous medical applications. Methods for making and using the micronized compositions are also described herein.
    Type: Application
    Filed: October 18, 2018
    Publication date: March 21, 2019
    Applicant: MiMedx Group, Inc.
    Inventors: Brenda S. Morse, Somaly Sith, Randall Spencer, Steven Ray, John Daniel, Robert Tofe
  • Tissue grafts modified with a cross-linking agent and method of making and using the same
    Patent number: 10232085
    Abstract: Described herein are tissue grafts derived from the placenta that possess good adhesion to biological tissues and are useful in would healing applications. In one aspect, the tissue graft includes (1) two or more layers of amnion, wherein at least one layer of amnion is cross-linked, (2) two or more layers of chorion, wherein at least one layer of amnion is cross-linked, or (3) one or more layers of amnion and chorion, wherein at least one layer of amnion and/or chorion is cross-linked. In another aspect, the grafts are composed of amnion and chorion cross-linked with one another. In a further aspect, the grafts have one or more layers sandwiched between the amnion and chorion membranes. The amnion and/or the chorion are treated with a cross-linking agent prior to the formation of the graft. The presence of the cross-linking agent present on the graft also enhances adhesion to the biological tissue of interest. Also described herein are methods for making and using the tissue grafts.
    Type: Grant
    Filed: March 18, 2016
    Date of Patent: March 19, 2019
    Assignee: MiMedx Group, Inc.
    Inventors: Brenda S. Morse, Somaly Sith, Randall Spencer, John Daniel
  • MICRONIZED PLACENTAL TISSUE COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20190046585
    Abstract: Described herein are compositions composed of micronized placental components and pharmaceutical compositions thereof. The compositions have numerous medical applications. Methods for making and using the micronized compositions are also described herein.
    Type: Application
    Filed: October 18, 2018
    Publication date: February 14, 2019
    Inventors: Brenda S. Morse, Somaly Sith, Randall Spencer, Steven Ray, John Daniel, Robert Tofe
  • Micronized placental tissue compositions and methods of making and using the same
    Patent number: 10105397
    Abstract: Described herein are compositions composed of micronized placental components and pharmaceutical compositions thereof. The compositions have numerous medical applications. Methods for making and using the micronized compositions are also described herein.
    Type: Grant
    Filed: March 6, 2013
    Date of Patent: October 23, 2018
    Assignee: MiMedx Group, Inc.
    Inventors: Brenda S. Morse, Somaly Sith, Randall Spencer, Steven Ray, John Daniel, Robert Tofe
  • Micronized placental tissue compositions and methods of making and using the same
    Patent number: 10105398
    Abstract: Described herein are compositions composed of micronized placental components and pharmaceutical compositions thereof. The compositions have numerous medical applications. Methods for making and using the micronized compositions are also described herein.
    Type: Grant
    Filed: May 23, 2014
    Date of Patent: October 23, 2018
    Assignee: MiMedx Group, Inc.
    Inventors: Brenda S. Morse, Somaly Sith, Randall Spencer, Steven Ray, John Daniel, Robert Tofe