Patents by Inventor Brenda Stevens

Brenda Stevens has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-ASGR1 ANTIBODY CONJUGATES AND USES THEREOF
    Publication number: 20230062712
    Abstract: The disclosure provides conjugates of anti-ASGR1 antibodies or antigen binding fragments thereof to a myeloid cell agonist, compositions comprising the conjugates, and methods of treating liver viral infections with the conjugates. The disclosure also provides for anti-ASGR1 antibodies or antigen binding fragments thereof and methods for using the antibodies or antigen binding fragments thereof in treating liver viral infections.
    Type: Application
    Filed: December 9, 2021
    Publication date: March 2, 2023
    Inventors: Peter R. Baum, Robert Dubose, Valerie Odegard, Philip Tan, Peter A. Thompson, Sean W. Smith, Brenda Stevens
  • Anti-ASGR1 antibody TLR8 agonist comprising conjugates and uses thereof
    Patent number: 11541126
    Abstract: The disclosure provides conjugates of anti-ASGR1 antibodies or antigen binding fragments thereof to a myeloid cell agonist, compositions comprising the conjugates, and methods of treating liver viral infections with the conjugates. The disclosure also provides for anti-ASGR1 antibodies or antigen binding fragments thereof and methods for using the antibodies or antigen binding fragments thereof in treating liver viral infections.
    Type: Grant
    Filed: July 1, 2021
    Date of Patent: January 3, 2023
    Assignee: SILVERBACK THERAPEUTICS, INC.
    Inventors: Peter R. Baum, Robert Dubose, Valerie Odegard, Philip Tan, Peter A. Thompson, Sean W. Smith, Brenda Stevens
  • ANTI-MESOTHELIN ANTIBODIES AND IMMUNOCONJUGATES THEREOF
    Publication number: 20220249685
    Abstract: Anti-mesothelin antibodies and conjugates comprising such antibodies are disclosed herein as well as the use of such conjugates in the treatment of disease, such as cancer.
    Type: Application
    Filed: June 18, 2020
    Publication date: August 11, 2022
    Inventors: Brenda STEVENS, Peter Robert BAUM, Robert DUBOSE, Valerie ODEGARD
  • NECTIN-4 ANTIBODY CONJUGATES AND USES THEREOF
    Publication number: 20220105196
    Abstract: The present disclosure provides conjugates of anti-Nectin-4 antibodies or antigen binding fragments thereof to a myeloid cell agonist, compositions comprising the conjugates, and methods of treating cancer with the conjugates. The present disclosure also provides for anti-Nectin-4 antibodies or antigen binding fragments thereof and method for using the antibodies or antigen binding fragments thereof in treating cancer.
    Type: Application
    Filed: October 4, 2021
    Publication date: April 7, 2022
    Inventors: Peter R. Baum, Robert Dubose, Valerie Odegard, Brenda Stevens, Philip Tan
  • Nectin-4 antibody conjugates and uses thereof
    Patent number: 11179473
    Abstract: The present disclosure provides conjugates of anti-Nectin-4 antibodies or antigen binding fragments thereof to a myeloid cell agonist, compositions comprising the conjugates, and methods of treating cancer with the conjugates. The present disclosure also provides for anti-Nectin-4 antibodies or antigen binding fragments thereof and method for using the antibodies or antigen binding fragments thereof in treating cancer.
    Type: Grant
    Filed: February 19, 2021
    Date of Patent: November 23, 2021
    Assignee: Silverback Therapeutics, Inc.
    Inventors: Peter R. Baum, Robert Dubose, Valerie Odegard, Brenda Stevens, Philip Tan
  • NECTIN-4 ANTIBODY CONJUGATES AND USES THEREOF
    Publication number: 20210275683
    Abstract: The present disclosure provides conjugates of anti-Nectin-4 antibodies or antigen binding fragments thereof to a myeloid cell agonist, compositions comprising the conjugates, and methods of treating cancer with the conjugates. The present disclosure also provides for anti-Nectin-4 antibodies or antigen binding fragments thereof and method for using the antibodies or antigen binding fragments thereof in treating cancer.
    Type: Application
    Filed: February 19, 2021
    Publication date: September 9, 2021
    Inventors: Peter R. Baum, Robert Dubose, Valerie Odegard, Brenda Stevens, Philip Tan
  • TGFßR1 INHIBITOR-ASGR ANTIBODY CONJUGATES AND USES THEREOF
    Publication number: 20210130473
    Abstract: Various conjugates and compositions thereof are disclosed for use in the treatment of a liver disease, such as liver cancer and liver fibrosis. The compositions comprise conjugates, wherein the conjugates are comprised of an antibody or antibody construct specific for ASGR1 or ASGR2 attached to a TGF?R1 inhibitor via a linker. Additionally provided are the methods of preparation of the conjugates and compositions thereof.
    Type: Application
    Filed: October 9, 2020
    Publication date: May 6, 2021
    Inventors: Peter R. BAUM, Robert DUBOSE, Valerie ODEGARD, Philip TAN, Peter A. THOMPSON, Sean W. SMITH, Brenda STEVENS
  • TRUNCATED IL-17RA SOLUBLE RECEPTOR AND METHODS OF USING IN INFLAMMATION
    Publication number: 20070197441
    Abstract: The present invention relates to blocking, inhibiting, reducing, antagonizing or neutralizing the activity of IL-17A alone, or both IL-17A and IL-17F polypeptide molecules. IL-17A and IL-17F are cytokines that are involved in inflammatory processes and human disease. IL-17RA is a receptor for IL-17A and does also bind IL-17F. The present invention includes a truncated soluble IL-17RA, as well as methods for antagonizing IL-17A or both IL-17A and IL-17F using such a truncated soluble receptor.
    Type: Application
    Filed: February 12, 2007
    Publication date: August 23, 2007
    Inventors: Mark Rixon, Zeren Gao, Steven Levin, Brenda Stevens
  • Method and apparatus for improved keyboard accessibility using vibrating keys
    Publication number: 20040183783
    Abstract: A keyboard in which one or more individual keys of the keyboard can be vibrated selectively. Thus, when a particular combination of keys or a single key needs to be activated, the user can identify the required key(s) by touch rather than by vision.
    Type: Application
    Filed: March 19, 2003
    Publication date: September 23, 2004
    Applicant: International Business Machines Corp.
    Inventors: Hypatia Rojas, Brenda Stevens Ryan, Barbara Elizabeth Wang