Patents by Inventor Brendan Blumenstiel

Brendan Blumenstiel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of diagnosing and treating medullary cystic kidney disease
    Patent number: 10370716
    Abstract: The present invention features a highly sensitive assay for detecting frameshift mutations for high throughput use. Also provided herein are methods for diagnosing or determining a predisposition for developing medullary cystic kidney disease type 1 (MCKD1) in a subject by detecting a frameshift mutation in the GC-rich variable number of tandem repeats (VNTR) sequence of the mucin 1 gene (MUC-1).
    Type: Grant
    Filed: February 10, 2015
    Date of Patent: August 6, 2019
    Assignees: THE BROAD INSTITUTE, INC., THE GENERAL HOSPITAL CORPORATION, INSTITUTO CARLOS SLIM DE LA SALUD, A.C.
    Inventors: Andrew Kirby, Andreas Gnirke, Brendan Blumenstiel, Matthew Defelice, Mark Daly
  • METHODS OF DIAGNOSING AND TREATING MEDULLARY CYSTIC KIDNEY DISEASE
    Publication number: 20150252423
    Abstract: The present invention features a highly sensitive assay for detecting frameshift mutations for high throughput use. Also provided herein are methods for diagnosing or determining a predisposition for developing medullary cystic kidney disease type 1 (MCKD1) in a subject by detecting a frameshift mutation in the GC-rich variable number of tandem repeats (VNTR) sequence of the mucin 1 gene (MUC-1).
    Type: Application
    Filed: February 10, 2015
    Publication date: September 10, 2015
    Inventors: Andrew KIRBY, Andreas GNIRKE, Brendan Blumenstiel, Matthew DEFELICE, Mark DALY