Abstract: An immersion liquid holder 2 is an immersion liquid holder that is used for an observation device 10 for observing sample S by using an immersion method, and includes a supporting member 2b configured to support an absorption member 3 that has absorbed an immersion liquid and a connection unit 2c configured to relatively fix the absorption member 3 that has absorbed the immersion liquid with respect to an optical system, which is an optical system included in the observation device 10, and to fix the absorption member 3 on an optical path of the optical system 1, by fixing the supporting member 2b to the observation device 10.

Abstract: A light sheet microscope comprises a detection optics with a tilted focal plane, and an illumination optics generating a tilted light sheet. The light sheet may be rotated about a rotation axis in order to match the tilted focal plane. A multiple sample carrier translates multiple samples through the tilted light sheet in a translation direction which is not in the plane of the light sheet, thereby enabling acquisition of three-dimensional images of each of the multiple samples in a single pass through the light sheet.

Abstract: Provided is a microscope including: a chamber storing a solution in which a cuvette accommodating a solution together with a sample is immersed and that has an index of refraction identical to that of the solution; an immersion objective lens being placed outside the chamber and collecting light from the sample; a camera acquiring an image of the light collected by the lens; a targeting section moving the lens in a direction along a detection light axis thereof; and a movable stage supporting the cuvette in the chamber so as to be movable in at least a direction along the detection light axis. Each of the cuvette and the chamber has a transparent section that can transmit light coming from the sample. The lens is placed so as to face the transparent section of the cuvette with the transparent section of the chamber interposed therebetween.

Abstract: Provided is a sample manufacturing method that includes: a step of forming a hanging drop consisting of a liquid drop of a medium solution in a hanging state while causing at least one cell aggregate to be encapsulated in the liquid drop of the medium solution, the medium solution becoming substantially transparent upon gelling or solidifying; and a step of causing the hanging drop to gel or solidify by causing a promoting factor that promotes gelling or solidification of the medium solution to act on the hanging drop.

Abstract: This inverted microscope comprises the following elements: an immersion objective lens, a medium container which is disposed above the immersion objective lens with a gap, and which has a bottom surface having a transparent portion and being capable of retaining a first immersion medium between the transparent portion and the immersion objective lens, and also which is capable of storing inside thereof a second immersion medium having a refractive index which is the same as or similar to that of the first immersion medium; and a movable stage to support a sample container, which accommodates a specimen, in a horizontally movable manner inside the medium container and which has a transparent portion in at least a part of a bottom surface thereof.

Abstract: An immersion liquid holder 2 is an immersion liquid holder that is used for an observation device 10 for observing sample S by using an immersion method, and includes a supporting member 2b configured to support an absorption member 3 that has absorbed an immersion liquid and a connection unit 2c configured to relatively fix the absorption member 3 that has absorbed the immersion liquid with respect to an optical system, which is an optical system included in the observation device 10, and to fix the absorption member 3 on an optical path of the optical system 1, by fixing the supporting member 2b to the observation device 10.

Abstract: This microplate includes: container sections having wells that open at a first plane and that accommodate samples; and a connection section connecting a plurality of rows of the container sections to be arrayed in a manner where the rows are spaced from each other in a direction along the first plane, wherein each of the container sections includes: at least one side wall section that is optically transparent at at least a portion thereof; and a bottom surface section that is disposed on a second plane on a side opposite from the first plane and that is optically transparent at at least a portion thereof, a recessed section is provided between neighboring rows of the container sections, and the recessed section allows an optical member to be inserted thereinto via the second plane, wherein the optical member introduces sheet-shaped illumination light to the well via the side wall section.

Abstract: Provided is a microscope including: a chamber storing a solution in which a cuvette accommodating a solution together with a sample is immersed and that has an index of refraction identical to that of the solution; an immersion objective lens being placed outside the chamber and collecting light from the sample; a camera acquiring an image of the light collected by the lens; a targeting section moving the lens in a direction along a detection light axis thereof; and a movable stage supporting the cuvette in the chamber so as to be movable in at least a direction along the detection light axis. Each of the cuvette and the chamber has a transparent section that can transmit light coming from the sample. The lens is placed so as to face the transparent section of the cuvette with the transparent section of the chamber interposed therebetween.

Abstract: This inverted microscope comprises the following elements: an immersion objective lens, a medium container which is disposed above the immersion objective lens with a gap, and which has a bottom surface having a transparent portion and being capable of retaining a first immersion medium between the transparent portion and the immersion objective lens, and also which is capable of storing inside thereof a second immersion medium having a refractive index which is the same as or similar to that of the first immersion medium; and a movable stage to support a sample container, which accommodates a specimen, in a horizontally movable manner inside the medium container and which has a transparent portion in at least a part of a bottom surface thereof.