Patents by Inventor Brendan FLOYD

Brendan FLOYD has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Molecular neighborhood detection by oligonucleotides
    Patent number: 12196760
    Abstract: The present disclosure provides methods for molecular neighborhood detection of molecules, such as by iterative proximity ligation or split-and-pool methods for obtaining positional information.
    Type: Grant
    Filed: January 11, 2021
    Date of Patent: January 14, 2025
    Assignee: Board of Regents, The University of Texas System
    Inventors: Edward Marcotte, Jagannath Swaminathan, Andrew Ellington, Alexander Boulgakov, Jon Laurent, Raghav Shroff, Erhu Xiong, Sanchita Bhadra, Brendan Floyd, Eric Anslyn
  • METHODS AND SYSTEMS FOR SINGLE CELL PROTEIN ANALYSIS
    Publication number: 20240168034
    Abstract: Methods and compositions for partitioning and analyzing cells are provided herein. The partitioning methods include encapsulating single cells in droplets, enabling biomolecule analysis at the single cell level. Further to this concept, multiple biomarkers can be quantified from single red blood cells, including methods which may determine whether a subject has undergone autologous blood transfer.
    Type: Application
    Filed: November 24, 2023
    Publication date: May 23, 2024
    Inventors: Eric V. ANSLYN, Edward MARCOTTE, Jagannath SWAMINATHAN, Cecil J. HOWARD, II, Angela BARDO, Vy Que Thanh DANG, Brendan FLOYD, Wisath SAE-LEE
  • METHODS, SYSTEMS AND KITS FOR POLYPEPTIDE PROCESSING AND ANALYSIS
    Publication number: 20240002925
    Abstract: Provided herein are compositions, systems, methods, and kits for peptide analysis, including peptide sequencing. Aspects of the present disclosure provide bifunctional reagents which may selectively couple to amino acids and selectively couple to detectable species. Aspects of the present disclosure further provide methods for using these bifunctional reagents to sequence and analyze peptides.
    Type: Application
    Filed: November 18, 2022
    Publication date: January 4, 2024
    Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Eric V. ANSLYN, Edward MARCOTTE, Cecil J. HOWARD, II, Jagannath SWAMINATHAN, Angela M. BARDO, Brendan FLOYD, Brandon HOSFORD, Le ZHANG, Emily Faith BABCOCK, Caroline M. HINSON
  • PEPTIDE AND PROTEIN C-TERMINUS LABELING
    Publication number: 20230076975
    Abstract: Described herein are methods for selectively cleaving the C-terminal amino acid of a peptide or protein. The methods described herein may be applicable for, for example, single-molecule peptide or protein sequencing.
    Type: Application
    Filed: August 18, 2022
    Publication date: March 9, 2023
    Inventors: Eric V. ANSLYN, Edward MARCOTTE, Cecil J. HOWARD, II, Jagannath SWAMINATHAN, Angela M. BARDO, Caroline M. HINSON, Brendan FLOYD, Le ZHANG
  • SINGLE MOLECULE SEQUENCING IDENTIFICATION OF POST-TRANSLATIONAL MODIFICATIONS ON PROTEINS
    Publication number: 20210215706
    Abstract: The present disclosure provides methods of selectively label an amino acid residue on a peptide by replacing a post translational modification with a labeling moiety and sequencing the peptide to obtain the location of the amino acid residue and the identity of the post translational modification. In some aspects, the disclosure also provides methods of identifying the position, quantity, the identity of a post translational modification, or any combination thereof, in peptides which may be used for therapeutic purposes.
    Type: Application
    Filed: January 22, 2021
    Publication date: July 15, 2021
    Applicant: Board of Regents, The University of Texas System
    Inventors: Edward MARCOTTE, Eric ANSLYN, Jagannath SWAMINATHAN, Angela M. BARDO, Caroline M. HINSON, Cecil HOWARD, Brendan FLOYD
  • MOLECULAR NEIGHBORHOOD DETECTION BY OLIGONUCLEOTIDES
    Publication number: 20210132076
    Abstract: The present disclosure provides methods for molecular neighborhood detection of molecules, such as by iterative proximity ligation or split-and-pool methods for obtaining positional information.
    Type: Application
    Filed: January 11, 2021
    Publication date: May 6, 2021
    Applicant: Board of Regents, The University of Texas System
    Inventors: Edward MARCOTTE, Jagannath SWAMINATHAN, Andrew ELLINGTON, Alexander BOULGAKOV, Jon LAURENT, Raghav SHROFF, Erhu XIONG, Sanchita BHADRA, Brendan FLOYD, Eric ANSLYN