Patents by Inventor Brendan KEATING

Brendan KEATING has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of micro-ribonucleic acid (miRNA) to diagnose transplant rejection and tolerance of immunosuppression therapy
    Publication number: 20240285200
    Abstract: The present invention relates to the discovery that the expression levels of some microRNAs (miRNAs) can use a diagnostic signature to predict transplant outcomes in a transplant recipient. Thus, in various embodiments described herein, the methods of the invention relate to methods of diagnosing a transplant subject for acute rejection such as acute cellular rejection (ACR), methods of predicting a subject's risk of having or developing ACR and methods of assessing in a subject the likelihood of a successful or failure minimization of immunosuppression therapy (IST) dosage from standard ranges.
    Type: Application
    Filed: April 24, 2024
    Publication date: August 29, 2024
    Inventors: Abraham SHAKED, Bao-Li CHANG, Brendan KEATING, Toumy GUETTOUCHE
  • USE OF MICRO-RIBONUCLEIC ACID (MIRNA) TO DIAGNOSE TRANSPLANT REJECTION AND TOLERANCE OF IMMUNOSUPPRESSION THERAPY
    Publication number: 20170032100
    Abstract: The present invention relates to the discovery that the expression levels of some microRNAs (miRNAs) can use a diagnostic signature to predict transplant outcomes in a transplant recipient. Thus, in various embodiments described herein, the methods of the invention relate to methods of diagnosing a transplant subject for acute rejection such as acute cellular rejection (ACR), methods of predicting a subject's risk of having or developing ACR and methods of assessing in a subject the likelihood of a successful or failure minimization of immunosuppression therapy (IST) dosage from standard ranges.
    Type: Application
    Filed: April 10, 2015
    Publication date: February 2, 2017
    Applicant: The Trustees of the University of Pennslyvania
    Inventors: Abraham SHAKED, Bao-Li CHANG, Brendan KEATING, Toumy GUETTOUCHE