Patents by Inventor Brendan Orner

Brendan Orner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Proteomimetic compounds and methods
    Patent number: 7312246
    Abstract: The present invention relates to compounds and pharmaceutical compositions which are proteonaimetic and to methods for inhibiting the interaction of an alpha-helical protein with another protein or binding site. Methods for treating diseases or conditions which are modulated through interactions between alpha helical proteins and their binding sites are other aspects of the invention. In particular, the invention relates to treatment of viral infections using terphenyl derivatives.
    Type: Grant
    Filed: January 25, 2005
    Date of Patent: December 25, 2007
    Assignee: Yale University
    Inventors: Andrew D. Hamilton, Justin Ernst, Brendan Orner
  • Defined surfaces of self-assembled monolayers and stem cells
    Publication number: 20070207543
    Abstract: A method for the construction of arrays from self-assembling monolayers is described. The arrays have particular utility for the screening of peptides ligands that can foster the growth of cells in culture. This technique has been used to identify peptide ligands that foster the growth of human stem cells, which otherwise require an extracellular matrix in order to grow in an undifferentiated state. This also makes possible an assay to identify other such peptides.
    Type: Application
    Filed: August 15, 2006
    Publication date: September 6, 2007
    Inventors: Laura Kiessling, Ratmir Derda, Brendan Orner, James Thomson
  • Proteomimetic compounds and methods
    Publication number: 20050215563
    Abstract: The present invention relates to compounds and pharmaceutical compositions which are proteomimetic and to methods for inhibiting the interaction of an alpha-helical protein with another protein or binding site. Methods for treating diseases or conditions which are modulated through interactions between alpha helical proteins and their binding sites are other aspects of the invention.
    Type: Application
    Filed: January 25, 2005
    Publication date: September 29, 2005
    Inventors: Andrew Hamilton, Justin Ernst, Brendan Orner