Patents by Inventor Brendon John Hanson

Brendon John Hanson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human monoclonal antibody with specificity for dengue virus serotype 1 E protein and uses thereof
    Patent number: 10294293
    Abstract: Compositions and methods for the treatment or prevention of Dengue virus infection in a vertebrate subject are provided. In particular, human neutralizing monoclonal antibodies to Dengue virus isolated from EBV immortalized B cells derived from patients who have recovered from Dengue infection are disclosed. Methods are provided for administering such antibodies to a vertebrate subject in an amount effective to reduce, eliminate, or prevent relapse from infection.
    Type: Grant
    Filed: June 1, 2016
    Date of Patent: May 21, 2019
    Assignees: National University of Singapore, DSO National Laboratories
    Inventors: Paul Anthony Macary, Ee Ping Evelyn Teoh, Brendon John Hanson, En Wei Teo, Angeline Pei Chiew Lim, Mah Lee Mary Ng, Shee Mei Lok, Petra Eveliina Kukkaro
  • HUMAN MONOCLONAL ANTIBODY WITH SPECIFICITY FOR DENGUE VIRUS SEROTYPE 1 E PROTEIN AND USES THEREOF
    Publication number: 20170029489
    Abstract: Compositions and methods for the treatment or prevention of Dengue virus infection in a vertebrate subject are provided. In particular, human neutralizing monoclonal antibodies to Dengue virus isolated from EBV immortalized B cells derived from patients who have recovered from Dengue infection are disclosed. Methods are provided for administering such antibodies to a vertebrate subject in an amount effective to reduce, eliminate, or prevent relapse from infection.
    Type: Application
    Filed: June 1, 2016
    Publication date: February 2, 2017
    Inventors: Paul Anthony Macary, Ee Ping Evelyn Teoh, Brendon John Hanson, En Wei Teo, Angeline Pei Chiew Lim, Mah Lee Mary Ng, Shee Mei Lok, Petra Eveliina Kukkaro
  • Human monoclonal antibody with specificity for Dengue virus serotype 1 E protein and uses thereof
    Patent number: 9376486
    Abstract: Compositions and methods for the treatment or prevention of Dengue virus infection in a vertebrate subject are provided. In particular, human neutralizing monoclonal antibodies to Dengue virus isolated from EBV immortalized B cells derived from patients who have recovered from Dengue infection are disclosed. Methods are provided for administering such antibodies to a vertebrate subject in an amount effective to reduce, eliminate, or prevent relapse from infection.
    Type: Grant
    Filed: December 14, 2011
    Date of Patent: June 28, 2016
    Assignees: National University of Singapore, DSO National Laboratories
    Inventors: Paul Anthony Macary, Ee Ping Evelyn Teoh, Brendon John Hanson, En Wei Teo, Angeline Pei Chiew Lim, Mah Lee Mary Ng, Shee Mei Lok, Petra Eveliina Kukkaro
  • Pathogenic mycobacteria-derived mannose-capped lipoarabinomannan antigen binding proteins
    Patent number: 9315566
    Abstract: Described herein are antigen binding proteins that bind to pathogenic mycobacteria-derived Mannose-Capped Lipoarabinomannan (ManLAM) and methods and kits for using and making the antigen binding proteins. Also described herein are antigen binding proteins that bind to the alpha 1-2 linkage mannose caps of ManLAM, antigen binding proteins that bind to a mannose cap with up to three alpha 1-2 linked mannose residues, and antigen binding proteins that bind to LAM with a mannose sugar capping motif.
    Type: Grant
    Filed: January 25, 2012
    Date of Patent: April 19, 2016
    Assignees: National University of Singapore, DSO National Laboratories
    Inventors: Paul Anthony Macary, Conrad En Zuo Chan, Brendon John Hanson, Markus R. Wenk
  • Pathogenic Mycobacteria-Derived Mannose-Capped Lipoarabinomannan Antigen Binding Proteins
    Publication number: 20130309237
    Abstract: Described herein are antigen binding proteins that bind to pathogenic mycobacteria-derived Mannose-Capped Lipoarabinomannan (ManLAM) and methods and kits for using and making the antigen binding proteins. Also described herein are antigen binding proteins that bind to the alpha 1-2 linkage mannose caps of ManLAM, antigen binding proteins that bind to a mannose cap with up to three alpha 1-2 linked mannose residues, and antigen binding proteins that bind to LAM with a mannose sugar capping motif.
    Type: Application
    Filed: January 25, 2012
    Publication date: November 21, 2013
    Applicants: DSO NATIONAL LABORATORIES, NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Paul Anthony Macary, Conrad En Zuo Chan, Brendon John Hanson, Markus R. Wenk
  • Human Monoclonal Antibody with Specificity for Dengue Virus Serotype 1 E Protein and Uses Thereof
    Publication number: 20130259871
    Abstract: Compositions and methods for the treatment or prevention of Dengue virus infection in a vertebrate subject are provided. In particular, human neutralizing monoclonal antibodies to Dengue virus isolated from EBV immortalized B cells derived from patients who have recovered from Dengue infection are disclosed. Methods are provided for administering such antibodies to a vertebrate subject in an amount effective to reduce, eliminate, or prevent relapse from infection.
    Type: Application
    Filed: December 14, 2011
    Publication date: October 3, 2013
    Applicants: DSO NATIONAL LABORATORIES, NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Paul Anthony Macary, Ee Ping Evelyn Teoh, Brendon John Hanson, En Wei Teo, Angeline Pei Chiew Lim, Mah Lee Mary Ng, Shee Mei Lok, Petra Eveliina Kukkaro
  • Method for Producing T Cell Receptor-Like Monoclonal Antibodies and Uses Thereof
    Publication number: 20120294874
    Abstract: Methods are provided for producing T cell receptor (TCR) like antibodies that recognize peptides displayed in the context of HLA molecules. Antibodies produced by methods provided herein have the specificity of a TCR and can be used as therapeutic, diagnostic and research reagents. Also provided are TCR-like antibodies which recognize Epstein-Barr virus (EBV) peptides displayed in the context of HLA molecules and are useful for the detection and treatment of EBV and EBV-linked diseases.
    Type: Application
    Filed: November 18, 2010
    Publication date: November 22, 2012
    Inventors: Paul Anthony Macary, Soh Ha Chan, Brendon John Hanson