Patents by Inventor Brendon Patierno

Brendon Patierno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Splice-switching oligonucleotides and methods of use
    Patent number: 12071626
    Abstract: The present disclosure provides methods and compositions for the treatment of cancer. In some aspects, the present disclosure provides splice-switching oligonucleotides that downregulate AR or EGFR expression and methods of using these splice-switching oligonucleotides to treat cancer.
    Type: Grant
    Filed: September 1, 2021
    Date of Patent: August 27, 2024
    Assignee: Duke University
    Inventors: Jennifer Freedman, Brendon Patierno, Bonnie LaCroix, Timothy Robinson, Bruce Sullenger, Daniel George, Steven Patierno
  • SPLICE-SWITCHING OLIGONUCLEOTIDES AND METHODS OF USE
    Publication number: 20240229028
    Abstract: The present disclosure provides methods and compositions for the treatment of cancer. In some aspects, the present disclosure provides splice-switching oligonucleotides that downregulate AR expression and methods of using these splice-switching oligonucleotides to treat cancer, specifically castrate resistant prostate cancer.
    Type: Application
    Filed: January 2, 2024
    Publication date: July 11, 2024
    Inventors: Jennifer Freedman, Steven Patierno, Daniel George, Bruce Sullenger, Bonnie LaCroix, Brendon Patierno
  • Splice-switching oligonucleotides and methods of use
    Patent number: 11866689
    Abstract: The present disclosure provides methods and compositions for the treatment of cancer. In some aspects, the present disclosure provides splice-switching oligonucleotides that downregulate AR expression and methods of using these splice-switching oligonucleotides to treat cancer, specifically castrate resistant prostate cancer.
    Type: Grant
    Filed: March 22, 2019
    Date of Patent: January 9, 2024
    Assignee: Duke University
    Inventors: Jennifer Freedman, Steven Patierno, Daniel George, Bruce Sullenger, Bonnie LaCroix, Brendon Patierno
  • SPLICE-SWITCHING OLIGONUCLEOTIDES AND METHODS OF USE
    Publication number: 20210395754
    Abstract: The present disclosure provides methods and compositions for the treatment of cancer. In some aspects, the present disclosure provides splice-switching oligonucleotides that downregulate AR or EGFR expression and methods of using these splice-switching oligonucleotides to treat cancer.
    Type: Application
    Filed: September 1, 2021
    Publication date: December 23, 2021
    Inventors: Jennifer Freedman, Brendon Patierno, Bonnie LaCroix, Timothy Robinson, Bruce Sullenger, Daniel George, Steven Patierno
  • Splice-switching oligonucleotides and methods of use
    Patent number: 11136584
    Abstract: The present disclosure provides methods and compositions for the treatment of cancer. In some aspects, the present disclosure provides splice-switching oligonucleotides that downregulate AR or EGFR expression and methods of using these splice-switching oligonucleotides to treat cancer.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: October 5, 2021
    Assignee: Duke University
    Inventors: Jennifer Freedman, Brendon Patierno, Bonnie Lacroix, Timothy Robinson, Bruce Sullenger, Daniel George, Steven Patierno
  • SPLICE-SWITCHING OLIGONUCLEOTIDES AND METHODS OF USE
    Publication number: 20210024932
    Abstract: The present disclosure provides methods and compositions for the treatment of cancer. In some aspects, the present disclosure provides splice-switching oligonucleotides that downregulate AR expression and methods of using these splice-switching oligonucleotides to treat cancer, specifically castrate resistant prostate cancer.
    Type: Application
    Filed: March 22, 2019
    Publication date: January 28, 2021
    Applicant: Duke University
    Inventors: Jennifer Freedman, Steven Patierno, Daniel George, Bruce Sullenger, Bonnie Lacroix, Brendon Patierno
  • Splice-Switching Oligonucleotides and Methods of Use
    Publication number: 20180334677
    Abstract: The present disclosure provides methods and compositions for the treatment of cancer. In some aspects, the present disclosure provides splice-switching oligonucleotides that downregulate AR or EGFR expression and methods of using these splice-switching oligonucleotides to treat cancer.
    Type: Application
    Filed: November 4, 2016
    Publication date: November 22, 2018
    Inventors: Jennifer Freedman, Brendon Patierno, Bonnie Lacroix, Timothy Robinson, Bruce Sullenger, Daniel George, Steven Patierno