Patents by Inventor Brendon Yew Loong Chua

Brendon Yew Loong Chua has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunogenic composition and uses thereof
    Patent number: 9889195
    Abstract: The present invention provides an immunogenic composition comprising an antigen and a dendritic cell targeting component. A charged group is covalently attached to a dendritic cell ligand and is electrostatically associated with the dendritic cell targeting component.
    Type: Grant
    Filed: January 22, 2015
    Date of Patent: February 13, 2018
    Assignee: INNAVAC PTY LTD
    Inventors: David Charles Jackson, Weiguang Zeng, Brendon Yew Loong Chua
  • IMMUNOLOGICAL REAGENT
    Publication number: 20170274068
    Abstract: The present invention provides an immunogenic composition comprising a charged antigen electrostatically associated with a Toll-Like Receptor (TLR) targeting moiety. The TLR targeting moiety comprises a TLR-2 agonist covalently attached to polyethylene glycol and to a hyper-branched charged peptide.
    Type: Application
    Filed: September 11, 2015
    Publication date: September 28, 2017
    Inventors: DAVID CHARLES JACKSON, BRENDON YEW LOONG CHUA, TOSHIKI SEKIYA
  • Method of transfection and compositions therefor
    Patent number: 9089508
    Abstract: The present invention relates to the targeted delivery of molecules to cells expressing toll-like receptors (TLRs). Aspects of the invention provide compounds comprising a positively charged group linked to a TLR ligand. These compounds are useful for in vitro and in vivo methods of transfection of TLR-expressing cells. Other aspects of the invention relate to the use of such compounds for repression of gene expression and DNA vaccination approaches.
    Type: Grant
    Filed: October 9, 2008
    Date of Patent: July 28, 2015
    Assignee: The University of Melbourne
    Inventors: David Charles Jackson, Weiguang Zeng, Brendon Yew Loong Chua
  • IMMUNOGENIC COMPOSITION AND USES THEREOF
    Publication number: 20150150966
    Abstract: The present invention provides an immunogenic composition comprising an antigen and a dendritic cell targeting component. A charged group is covalently attached to a dendritic cell ligand and is electrostatically associated with the dendritic cell targeting component.
    Type: Application
    Filed: January 22, 2015
    Publication date: June 4, 2015
    Inventors: DAVID CHARLES JACKSON, WEIGUANG ZENG, BRENDON YEW LOONG CHUA
  • Biopolymer hybrid gel-depot delivery system
    Patent number: 8945551
    Abstract: The invention relates to biopolymer-gel based depot systems for prolonged and/or controlled release delivery of biologically active agents, methods for the manufacture of the biopolymer based gel-depots which include a biologically active agent, and uses of such biopolymer gel-depots in therapy. The biopolymer-gel based depot systems comprise a biocompatible polyaminosaccharide and/or protein; a biocompatible phosphate and/or sulphonamide compound; a biologically active agent; an aqueous insoluble alkaline earth metal phosphate; and a biocompatible glycan and/or proteoglycan.
    Type: Grant
    Filed: July 9, 2010
    Date of Patent: February 3, 2015
    Assignee: Polymers CRC Ltd.
    Inventors: David Edward Mainwaring, Mohammad Al Kobaisi, Brendon Yew Loong Chua, David Charles Jackson
  • BIOPOLYMER HYBRID GEL-DEPOT DELIVERY SYSTEM
    Publication number: 20120251536
    Abstract: The invention relates to biopolymer-gel based depot systems for prolonged and/or controlled release delivery of biologically active agents, methods for the manufacture of the biopolymer based gel-depots which include a biologically active agent, and uses of such biopolymer gel-depots in therapy. The biopolymer-gel based depot systems comprise a biocompatible polyaminosaccharide and/or protein; a biocompatible phosphate and/or sulphonamide compound; a biologically active agent; an aqueous insoluble alkaline earth metal phosphate; and a biocompatible glycan and/or proteoglycan.
    Type: Application
    Filed: July 9, 2010
    Publication date: October 4, 2012
    Applicant: POLYMERS CRC LIMITED
    Inventors: David Edward Mainwaring, Mohammad Al Kobaisi, Brendon Yew Loong Chua, David Charles Jackson, Weiguang Zeng
  • IMMUNOGENIC COMPOSITION AND USES THEREOF
    Publication number: 20120064109
    Abstract: The present invention provides an immunogenic composition comprising an antigen and a dendritic cell targeting component. A charged group is covalently attached to a dendritic cell ligand and is electrostatically associated with the dendritic cell targeting component.
    Type: Application
    Filed: October 7, 2011
    Publication date: March 15, 2012
    Applicant: THE UNIVERSITY OF MELBOURNE
    Inventors: David Charles Jackson, Weiguang Zeng, Brendon Yew Loong Chua
  • METHOD OF TRANSFECTION AND COMPOSITIONS THEREFOR
    Publication number: 20100310595
    Abstract: The present invention relates to the targeted delivery of molecules to cells expressing toll-like receptors (TLRs). Aspects of the invention provide compounds comprising a positively charged group linked to a TLR ligand. These compounds are useful for in vitro and in vivo methods of transfection of TLR-expressing cells. Other aspects of the invention relate to the use of such compounds for repression of gene expression and DNA vaccination approaches.
    Type: Application
    Filed: October 9, 2008
    Publication date: December 9, 2010
    Inventors: David Charles Jackson, Weiguang Zeng, Brendon Yew Loong Chua