Patents by Inventor Brenna Hearn Lord
Brenna Hearn Lord has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230158491Abstract: The present application is generally directed to systems, methods, and devices for diagnostics for sensing and/or identifying pathogens, genomic materials, proteins, and/or other small molecules or biomarkers. In some implementations, a small footprint low cost device provides rapid and robust sensing and identification. Such a device may utilize microfluidics, biochemistry, and electronics to detect one or more targets at once in the field and closer to or at the point of care.Type: ApplicationFiled: September 26, 2022Publication date: May 25, 2023Inventors: Shad Pierson, Timothy D. Meehan, Kyle William Montgomery, Daniel J. Wade, Jess M. Sustarich, Brenna Hearn Lord, Ronald Philip Chiarello
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Patent number: 11465141Abstract: The present application is generally directed to systems, methods, and devices for diagnostics for sensing and/or identifying pathogens, genomic materials, proteins, and/or other small molecules or biomarkers. In some implementations, a small footprint low cost device provides rapid and robust sensing and identification. Such a device may utilize microfluidics, biochemistry, and electronics to detect one or more targets at once in the field and closer to or at the point of care.Type: GrantFiled: September 20, 2017Date of Patent: October 11, 2022Assignee: ALVEO TECHNOLOGIES, INC.Inventors: Shad Pierson, Timothy D. Meehan, Kyle William Montgomery, Daniel J. Wade, Jess M. Sustarich, Brenna Hearn Lord, Ronald Phillip Chiarello
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Publication number: 20220073975Abstract: Some embodiments of the methods provided herein relate to amplifying and detecting a target nucleic acid. Some such embodiments include performing a recombinase polymerase amplification (RPA) and, optionally, a second isothermal amplification reaction. In some embodiments, the second isothermal amplification reaction includes loop-mediated isothermal amplification (LAMP). In some embodiments, the second isothermal amplification reaction is performed in conjunction with the RPA. In some embodiments, the second isothermal amplification reaction is performed on amplification products of the RPA. Some embodiments also include detecting the presence of amplification products by measuring a modulation of an electoral signal such as impedance.Type: ApplicationFiled: December 18, 2019Publication date: March 10, 2022Inventors: Rixun Fang, Joseph Carl Gaiteri, Brenna Hearn Lord, Yuh-Min Chiang, Ronald Phillip Chiarello
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Publication number: 20220056511Abstract: Embodiments relate to methods, systems and compositions for reducing nonspecific amplification in isothermal amplification reactions. Some embodiments relate to reducing nonspecific amplification in loop-mediated isothermal amplification (LAMP) reactions with certain oligonucleotides.Type: ApplicationFiled: December 18, 2019Publication date: February 24, 2022Inventors: Joseph Carl Gaiteri, Rixun Fang, Brenna Hearn Lord, Yuh-Min Chiang, Ronald Phillip Chiarello
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Publication number: 20190232282Abstract: The present application is generally directed to systems, methods, and devices for diagnostics for sensing and/or identifying pathogens, genomic materials, proteins, and/or other small molecules or biomarkers. In some implementations, a small footprint low cost device provides rapid and robust sensing and identification. Such a device may utilize microfluidics, biochemistry, and electronics to detect one or more targets at once in the field and closer to or at the point of care.Type: ApplicationFiled: September 20, 2017Publication date: August 1, 2019Inventors: Shad Pierson, Timothy D. Meehan, Kyle William Montgomery, Daniel J. Wade, Jess M. Sustarich, Brenna Hearn Lord, Ronald Philip Chiarello
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Patent number: 10357384Abstract: Polymeric stents having fracture toughness and resistance to recoil after deployment are disclosed along with methods of manufacturing such stents. Improvements to mechanical characteristics and other improvements may be achieved by having polymer chains within individual stent struts oriented in a direction that is closer to or in line with the axis of the individual stent struts. The struts are connected to each other by hinge elements that are configured to bend during crimping and deployment of the stent. Ring struts form ring structures. A ring structure can have an overall curvilinear length from about 12 mm to about 15 mm.Type: GrantFiled: June 29, 2015Date of Patent: July 23, 2019Assignee: ABBOTT CARDIOVASCULAR SYSTEM INC.Inventors: Brenna Hearn Lord, Nicole F. Perzov, Timothy A. Limon
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Patent number: 9572699Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. A sheath pair is placed over the crimped scaffold after crimping to reduce recoil of the crimped polymer scaffold and maintain scaffold-balloon engagement relied on to hold the scaffold to the balloon when the scaffold is being delivered to a target in a body. The sheath pair is removed by a health professional before placing the scaffold within the body.Type: GrantFiled: September 3, 2014Date of Patent: February 21, 2017Assignee: ABBOTT CARDIOVASCULAR SYSTEMS INC.Inventors: Annie P. Liu, Jason Phillips, Mark C. Johnson, Brenna Hearn Lord, Jeremy Beer, Travis Yribarren, Steve Saville, Marc L. Speck
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Patent number: 9211204Abstract: A pattern is used to form a stent scaffold from a polymeric precursor tube having a particular outer diameter. A new pattern can be derived from a base pattern, wherein the new pattern can be used to form a stent scaffold from a precursor tube having an outer diameter ODPR smaller than that needed for the base pattern. The new pattern can be derived by determining the shape of a stent scaffold, having the base pattern, after having been radially compressed to ODPR. The radially compressed shape is used to design the new pattern, which is applied to a precursor tube having an outer diameter ODPR. The new pattern can have a plurality of W-shaped closed cells, each W-shape closed cell bounded by struts oriented in such a way to form interior angles from about 80 degrees to about 95 degrees between every two adjacent struts.Type: GrantFiled: July 25, 2013Date of Patent: December 15, 2015Assignee: Abbott Cardiovascular Systems Inc.Inventor: Brenna Hearn Lord
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Publication number: 20150297372Abstract: Polymeric stents having fracture toughness and resistance to recoil after deployment are disclosed along with methods of manufacturing such stents. Improvements to mechanical characteristics and other improvements may be achieved by having polymer chains within individual stent struts oriented in a direction that is closer to or in line with the axis of the individual stent struts. The struts are connected to each other by hinge elements that are configured to bend during crimping and deployment of the stent. Ring struts form ring structures. A ring structure can have an overall curvilinear length from about 12 mm to about 15 mm.Type: ApplicationFiled: June 29, 2015Publication date: October 22, 2015Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.Inventors: Brenna Hearn Lord, Nicole F. Perzov, Timothy A. Limon
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Patent number: 9079354Abstract: Polymeric stents having fracture toughness and resistance to recoil after deployment are disclosed along with methods of manufacturing such stents. Improvements to mechanical characteristics and other improvements may be achieved by having polymer chains within individual stent struts oriented in a direction that is closer to or in line with the axis of the individual stent struts. The struts are connected to each other by hinge elements that are configured to bend during crimping and deployment of the stent. Ring struts form ring structures. A ring structure can have an overall curvilinear length from about 12 mm to about 15 mm.Type: GrantFiled: October 31, 2012Date of Patent: July 14, 2015Assignee: Abbott Cardiovascular Systems Inc.Inventors: Brenna Hearn Lord, Nicole F. Perzov, Timothy A. Limon
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Publication number: 20150088241Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. A sheath pair is placed over the crimped scaffold after crimping to reduce recoil of the crimped polymer scaffold and maintain scaffold-balloon engagement relied on to hold the scaffold to the balloon when the scaffold is being delivered to a target in a body. The sheath pair is removed by a health professional before placing the scaffold within the body.Type: ApplicationFiled: September 3, 2014Publication date: March 26, 2015Inventors: Annie P. Liu, Jason Phillips, Mark C. Johnson, Brenna Hearn Lord, Jeremy Beer, Travis Yribarren, Steve Saville, Marc L. Speck
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Patent number: 8852257Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. A sheath pair is placed over the crimped scaffold after crimping to reduce recoil of the crimped polymer scaffold and maintain scaffold-balloon engagement relied on to hold the scaffold to the balloon when the scaffold is being delivered to a target in a body. The sheath pair is removed by a health professional before placing the scaffold within the body.Type: GrantFiled: June 21, 2011Date of Patent: October 7, 2014Assignee: Abbott Cardiovascular Systems Inc.Inventors: Annie P. Liu, Jason Phillips, Mark C. Johnson, Brenna Hearn Lord, Jeremy Beer, Travis Yribarren, Steve Saville, Marc L. Speck
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Publication number: 20130310921Abstract: A pattern is used to form a stent scaffold from a polymeric precursor tube having a particular outer diameter. A new pattern can be derived from a base pattern, wherein the new pattern can be used to form a stent scaffold from a precursor tube having an outer diameter ODPR smaller than that needed for the base pattern. The new pattern can be derived by determining the shape of a stent scaffold, having the base pattern, after having been radially compressed to ODPR. The radially compressed shape is used to design the new pattern, which is applied to a precursor tube having an outer diameter ODPR. The new pattern can have a plurality of W-shaped closed cells, each W-shape closed cell bounded by struts oriented in such a way to form interior angles from about 80 degrees to about 95 degrees between every two adjacent struts.Type: ApplicationFiled: July 25, 2013Publication date: November 21, 2013Inventor: Brenna Hearn Lord
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Patent number: 8495904Abstract: A pattern is used to form a stent scaffold from a polymeric precursor tube having a particular outer diameter. A new pattern can be derived from a base pattern, wherein the new pattern can be used to form a stent scaffold from a precursor tube having an outer diameter ODPR smaller than that needed for the base pattern. The new pattern can be derived by determining the shape of a stent scaffold, having the base pattern, after having been radially compressed to ODPR. The radially compressed shape is used to design the new pattern, which is applied to a precursor tube having an outer diameter ODPR. The new pattern can have a plurality of W-shaped closed cells, each W-shape closed cell bounded by struts oriented in such a way to form interior angles from about 80 degrees to about 95 degrees between every two adjacent struts.Type: GrantFiled: February 4, 2013Date of Patent: July 30, 2013Assignee: Abbott Cardiovascular Systems Inc.Inventor: Brenna Hearn Lord
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Patent number: 8370120Abstract: A pattern is used to form a stent scaffold from a polymeric precursor tube having a particular outer diameter. A new pattern can be derived from a base pattern, wherein the new pattern can be used to form a stent scaffold from a precursor tube having an outer diameter ODPR smaller than that needed for the base pattern. The new pattern can be derived by determining the shape of a stent scaffold, having the base pattern, after having been radially compressed to ODPR. The radially compressed shape is used to design the new pattern, which is applied to a precursor tube having an outer diameter ODPR. The new pattern can have a plurality of W-shaped closed cells, each W-shape closed cell bounded by struts oriented in such a way to form interior angles from about 80 degrees to about 95 degrees between every two adjacent struts.Type: GrantFiled: April 30, 2010Date of Patent: February 5, 2013Assignee: Abbott Cardiovascular Systems Inc.Inventor: Brenna Hearn Lord
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Publication number: 20120324696Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. A sheath pair is placed over the crimped scaffold after crimping to reduce recoil of the crimped polymer scaffold and maintain scaffold-balloon engagement relied on to hold the scaffold to the balloon when the scaffold is being delivered to a target in a body. The sheath pair is removed by a health professional before placing the scaffold within the body.Type: ApplicationFiled: June 21, 2011Publication date: December 27, 2012Applicant: Abbott Cardiovascular Systems Inc.Inventors: Annie P. Liu, Jason Phillips, Mark C. Johnson, Brenna Hearn Lord, Jeremy Beer, Travis Yribarren, Steve Saville, Marc L. Speck
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Patent number: 8303644Abstract: Polymeric stents having fracture toughness and resistance to recoil after deployment are disclosed along with methods of manufacturing such stents. Improvements to mechanical characteristics and other improvements may be achieved by having polymer chains within individual stent struts oriented in a direction that is closer to or in line with the axis of the individual stent struts. The struts are connected to each other by hinge elements that are configured to bend during crimping and deployment of the stent. The hinge elements may be tangent or non-tangent to the adjoining struts so as to form W-shaped closed cells arranged in an offset brick pattern in which the size each W-shaped closed cell can be defined in part by a curvilinear length that is approximately 4.5 mm, which allows the stent to be crimped down to an OD of about 1.3 mm and expanded to an OD of at least about 3.5 mm.Type: GrantFiled: July 7, 2010Date of Patent: November 6, 2012Assignee: Abbott Cardiovascular Systems Inc.Inventors: Brenna Hearn Lord, Nicole F. Hou, Timothy A. Limon
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Publication number: 20110270384Abstract: A pattern is used to form a stent scaffold from a polymeric precursor tube having a particular outer diameter. A new pattern can be derived from a base pattern, wherein the new pattern can be used to form a stent scaffold from a precursor tube having an outer diameter ODPR smaller than that needed for the base pattern. The new pattern can be derived by determining the shape of a stent scaffold, having the base pattern, after having been radially compressed to ODPR. The radially compressed shape is used to design the new pattern, which is applied to a precursor tube having an outer diameter ODPR. The new pattern can have a plurality of W-shaped closed cells, each W-shape closed cell bounded by struts oriented in such a way to form interior angles from about 80 degrees to about 95 degrees between every two adjacent struts.Type: ApplicationFiled: April 30, 2010Publication date: November 3, 2011Inventor: Brenna Hearn Lord
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Publication number: 20100274349Abstract: Polymeric stents having fracture toughness and resistance to recoil after deployment are disclosed along with methods of manufacturing such stents. Improvements to mechanical characteristics and other improvements may be achieved by having polymer chains within individual stent struts oriented in a direction that is closer to or in line with the axis of the individual stent struts. The struts are connected to each other by hinge elements that are configured to bend during crimping and deployment of the stent. The hinge elements may be tangent or non-tangent to the adjoining struts so as to form W-shaped closed cells arranged in an offset brick pattern in which the size each W-shaped closed cell can be defined in part by a curvilinear length that is approximately 4.5 mm, which allows the stent to be crimped down to an OD of about 1.3 mm and expanded to an OD of at least about 3.5 mm.Type: ApplicationFiled: July 7, 2010Publication date: October 28, 2010Inventors: Brenna Hearn Lord, Nicole F. Hou, Timothy A. Limon