Patents by Inventor Brent A. Dethlefs

Brent A. Dethlefs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Organotypic slices of the central nervous system
    Patent number: 8198083
    Abstract: An organotypic slice and a method of preparing an organotypic slice from a central nervous system tissue, wherein the organotypic slice comprises a brain slice obtained from a brain wherein mature synapses have not been established and the organotypic slice is seeded with a population of stem cells; wherein the organotypic slice has enhanced viability as compared to an organotypic slice comprising a similar brain slice not seeded with a population of stem cells.
    Type: Grant
    Filed: October 31, 2008
    Date of Patent: June 12, 2012
    Inventors: William Gunter Loudon, Shengwen Li, Brent A. Dethlefs
  • Assay, methods and products based on n K.sup.+ channel expression
    Patent number: 5827655
    Abstract: This disclosure relates to the n K.sup.+ channel expression product of the MK3 gene or a functionally bioactive equivalent thereof and its uses, particulary in combination with identifying immune responses and materials modulating or blocking same.
    Type: Grant
    Filed: September 12, 1995
    Date of Patent: October 27, 1998
    Assignee: The Regents of the University of California
    Inventors: Kanianthara G. Chandy, Michael D. Cahalan, Stephan Grissmer, Alan L. Goldin, Brent A. Dethlefs, George A. Gutman, John J. Wasmuth
  • Assay for and treatment of autoimmune diseases
    Patent number: 5397702
    Abstract: This disclosure relates to the general diagnosis and treatment of autoimmune diseases with materials identified in assays based upon the finding herein that such diseases manifest by elevated numbers of type l K.sup.+ channels in abnormal CD4.sup.- CD8.sup.- T cells.
    Type: Grant
    Filed: October 2, 1992
    Date of Patent: March 14, 1995
    Assignee: The Regents of the University of California
    Inventors: Michael D. Cahalan, Kanianthara G. Chandy, Stephan Grissmer, Sanjiu Ghanshani, George A. Gutman, Brent A. Dethlefs