Abstract: Described herein are compositions and their use in methods and pharmaceutical compositions for inhibiting the binding between Yes-associated protein and TEA domain. Also, described herein are methods of using said compositions capable of inhibiting the binding between Yes-associated protein and TEA domain to treat cancer, inhibit cell proliferation, cell migration, cell invasiveness and tumor growth.

Abstract: This disclosure relates to inhibitors of IRES-mediated protein synthesis, compositions comprising therapeutically effective amounts of these compounds, and methods of using those compounds and compositions in treating hyperproliferative disorders, e.g., cancers. This disclosure also relates to compositions comprising inhibitors of IRES-mediated protein synthesis and mTOR inhibitors, and to methods of treating cancer by conjoint administration of inhibitors of IRES-mediated protein synthesis and mTOR inhibitors.

Abstract: A product display system and method. The system includes: a housing configured to contain a product; a power module that provides electrical power; an electronic paper display module that visually displays images; an operating module that controls image displays; a memory module that stores images; an activation module that selectably restricts power consumption; a transceiver module that transmits and receives signals, and alters an image display upon receipt of a signal; a remote control module that enables a user to selectably transmit a signal; and a signal converting module that alters a state of a signal. The method steps include: providing a product; coupling a product display system to the product; subscribing to at least one of a plurality of image content providers; receiving a wireless signal from an image content provider; converting a signal to an image; storing an image; displaying an image; and deleting a displayed image.

Abstract: There is a product display system and container for holding contents. The container includes a housing configured to contain the product; a power source coupled to the housing and configured to provide electrical power; an electronic paper display coupled to the housing, electrically coupled to the power source, and configured to visually display first and second images; a processor in electrical communication with the electronic paper display and configured to control display of the first and second images; and/or a memory module in communication with the electronic paper display and configured to store information regarding the first and second images. There is an activation module in electrical communication with the electronic paper display, the processor, and the power source, wherein the activation module is configured to selectably restrict power consumption from the power source. There is also a solar cell for recharging the power source.

Abstract: A system for searching for vendor products including a consultant data store, a search engine, and a client interface having an input section and a result section. The consultant data store can be populated with standardized product characteristics for a plurality of products supplied by different vendors. The search engine can compare customer preferences against product characteristic contained in the consultant data store. The input section can be configured for customers to enter customer preferences into a plurality of consultant established fields. The result section can be configured to present a plurality of vendor products based upon search engine results, wherein an indicator based upon a level of correspondence between customer preferences and product characteristics is displayed next to each vendor product. In one embodiment, the products can be electronic medical record products and the client interface can be a Web-based interface configured for health care providers.