Patents by Inventor Brent R. DeGeorge, Jr.

Brent R. DeGeorge, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11832860
    Abstract: A method and system for promoting the union of a bone fracture and/or fusion of bones across a joint space at a target region of a subject which may be accomplished by: inserting a surgical implant device at the target region; providing a guide member in the surgical implant device bore; sealing the surgical implant device bore distal opening and/or the surgical implant device bore proximal opening with the guide member; and positioning the guide member relative to the surgical implant device to provide for the guide member to be partially absent from the surgical implant device bore to allow the biomaterial and/or biologically active agents to extrude or diffuse from the activated apertures to the target region of the subject.
    Type: Grant
    Filed: June 21, 2019
    Date of Patent: December 5, 2023
    Assignee: University of Virginia Patent Foundation
    Inventors: Brent R. DeGeorge, Jr., Patrick S. Cottler
  • Publication number: 20230001055
    Abstract: Provided are compositions that can be employed for generating microporous gel systems. In some embodiments, the compositions include at least one sub-population of soft hydrogel microparticles with a Youngs modulus of less than 50 kPa and at least one sub-population of stiff hydrogel microparticles with a Young's modulus of greater than 90 kPa. Also provided are methods for generating the compositions, methods for treating bone and/or cartilage defects in subject using the disclosed compositions, methods for treating osteoarthritis using the disclosed compositions, and methods for providing orthopedic implants to subjects.
    Type: Application
    Filed: December 7, 2020
    Publication date: January 5, 2023
    Applicant: University of Virginia Patent Foundation
    Inventors: Donald Richieri Griffin, Blaise N. Pfaff, Nicholas J. Cornell, Brent R. DeGeorge, JR.
  • Publication number: 20210244453
    Abstract: A method and system for promoting the union of a bone fracture and/or fusion of bones across a joint space at a target region of a subject which may be accomplished by: inserting a surgical implant device at the target region; providing a guide member in the surgical implant device bore; sealing the surgical implant device bore distal opening and/or the surgical implant device bore proximal opening with the guide member; and positioning the guide member relative to the surgical implant device to provide for the guide member to be partially absent from the surgical implant device bore to allow the biomaterial and/or biologically active agents to extrude or diffuse from the activated apertures to the target region of the subject.
    Type: Application
    Filed: June 21, 2019
    Publication date: August 12, 2021
    Applicant: University of Virginia Patent Foundation
    Inventors: Brent R. DeGeorge, Jr., Patrick S. Cottler