Abstract: A formulation for maintaining physiological resilience during conditions of sustained physical activity can include a carbohydrate blend, a fatty-acid blend, and an amino-acid blend in a powder form that immediately dissolves in fluid water. The carbohydrate blend can include simple and complex carbohydrates providing less than 70% of total calories of a complete meal in a complete meal-equivalent (“CME”) dose of the formulation. The fatty-acid blend can include medium-chain fatty acids, long-chain fatty acids, and very-long-chain fatty acids. The fatty-acid blend can provide less than 50% of the total calories of the complete meal in the CME dose of the formulation. The amino-acid blend can include essential amino acids (“EAAs”) and non-essential amino acids. The EAAs can provide 60-80% by weight of the amino-acid blend. The EAAs can provide less than 30% of the total calories of the complete meal in the CME dose of the formulation.

Abstract: A composition of bio-active compounds and methods for facilitating and supporting the metabolism and transport of glucose and carbohydrates into muscle cells, promoting muscle function and growth, promoting glycogen synthesis, enhancing glucose disposal, stimulating pancreatic beta cells, promoting metabolic recovery, promoting muscle recovery, promoting lean body mass, and promoting fat burning. Preferably, the composition of bio-active compounds includes a combination of 4-hydroxyisoleucine with at least one amino acid selected from the group consisting of arginine, aspartate, threonine, serine, glutamate, proline, glycine, alanine, cysteine, valine, methionine, isoleucine, leucine, tryptophan, phenylalanine, ornithine, lysine, histidine, gamma-amino butyrate and tyrosine. In one presently preferred embodiment of the present invention, the combination is derived, isolated, and/or extracted from fenugreek seeds.