Patents by Inventor Brent Welborn

Brent Welborn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF DETERMINING EXPOSURE TO UV LIGHT
    Publication number: 20210239521
    Abstract: Methods of determining the dose of UVC light delivered to a sample comprising a low optical transmission complex fluid are provided. Also provided are methods of inactivation of an organism, such as a spore, a bacteria or a virus, in a sample comprising dose of UVC light delivered to a sample comprising a low optical transmission complex fluid.
    Type: Application
    Filed: February 10, 2021
    Publication date: August 5, 2021
    Applicant: AMGEN INC.
    Inventors: Roger HART, Amanda LEWIS, Brent WELBORN
  • Methods of determining exposure to UV light
    Patent number: 10955291
    Abstract: Methods of determining the dose of UVC light delivered to a sample comprising a low optical transmission complex fluid are provided. Also provided are methods of inactivation of an organism, such as a spore, a bacteria or a virus, in a sample comprising dose of UVC light delivered to a sample comprising a low optical transmission complex fluid.
    Type: Grant
    Filed: March 7, 2013
    Date of Patent: March 23, 2021
    Assignee: AMGEN INC.
    Inventors: Roger Hart, Amanda Lewis, Brent Welborn
  • Methods of reducing or eliminating protein modification and degradation arising from exposure to UV light
    Patent number: 10634589
    Abstract: Methods of inactivation of a virus in a sample comprising a protein component are provided. Also provided are methods of reducing protein degradation or modification in to the presence of a reactive species, such as a reactive species generated as a result of UV exposure, are also provided. In another aspect, a method of reducing oxidation of methionine residues, tryptophan residues or both methionine and tryptophan residues in a protein subjected to UV light is provided. The disclosed methods can be performed at any scale and can be automated as desired.
    Type: Grant
    Filed: October 25, 2012
    Date of Patent: April 28, 2020
    Assignee: AMGEN INC.
    Inventors: Joseph Edward Shultz, Roger Hart, Brent Welborn
  • METHODS OF DETERMINING EXPOSURE TO UV LIGHT
    Publication number: 20150053546
    Abstract: Methods of determining the dose of UVC light delivered to a sample comprising a low optical transmission complex fluid are provided. Also provided are methods of inactivation of an organism, such as a spore, a bacteria or a virus, in a sample comprising dose of UVC light delivered to a sample comprising a low optical transmission complex fluid.
    Type: Application
    Filed: March 7, 2013
    Publication date: February 26, 2015
    Applicant: Amgen Inc.
    Inventors: Roger Hart, Amanda Lewis, Brent Welborn
  • METHODS OF REDUCING OR ELIMINATING PROTEIN MODIFICATION AND DEGRADATION ARISING FROM EXPOSURE TO UV LIGHT
    Publication number: 20140329227
    Abstract: Methods of inactivation of a virus in a sample comprising a protein component are provided. Also provided are methods of reducing protein degradation or modification in to the presence of a reactive species, such as a reactive species generated as a result of UV exposure, are also provided. In another aspect, a method of reducing oxidation of methionine residues, tryptophan residues or both methionine and tryptophan residues in a protein subjected to UV light is provided. The disclosed methods can be performed at any scale and can be automated as desired.
    Type: Application
    Filed: October 25, 2012
    Publication date: November 6, 2014
    Inventors: Joseph Edward Ssultz, Roger Hart, Brent Welborn