Patents by Inventor Brenton DeBoef

Brenton DeBoef has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Rotaxane-type probe for molecular imaging
    Patent number: 11045561
    Abstract: The invention provides a novel method for synthesizing hyperpolarized xenon-129 (HP Xe) biosensors by using pseudo-rotaxane structures of gamma-cyclodextrin. These supramolecular complexes form novel ternary structures in the presence of HP Xe which can be detected via 129Xe MR spectroscopy and imaging techniques. The rotaxane-type complex can be tagged with an affinity label for detecting a target in a biological subject.
    Type: Grant
    Filed: March 28, 2018
    Date of Patent: June 29, 2021
    Assignee: University of Rhode Island Board of Trustees
    Inventors: Brenton DeBoef, Ashvin Fernando
  • Novel Rotaxane-Type Probe For Molecular Imaging
    Publication number: 20190101545
    Abstract: The invention provides a novel method for synthesizing hyperpolarized xenon-129 (HP Xe) biosensors by using pseudo-rotaxane structures of gamma-cyclodextrin. These supramolecular complexes form novel ternary structures in the presence of HP Xe which can be detected via 129Xe MR spectroscopy and imaging techniques. The rotaxane-type complex can be tagged with an affinity label for detecting a target in a biological subject.
    Type: Application
    Filed: March 28, 2018
    Publication date: April 4, 2019
    Inventors: Brenton DeBoef, Ashvin Fernando
  • Aerobic oxidative coupling for the formation of biaryls
    Patent number: 8703966
    Abstract: A method of catalytic oxidative coupling for the formation of hetero-coupled bis-arenes. The method includes placing a solvent, an arene compound, and a catalyst in a reactor having a oxidant atmosphere such that hetero-coupled bis-arenes are formed.
    Type: Grant
    Filed: April 30, 2009
    Date of Patent: April 22, 2014
    Assignee: Board of Governors for Higher Education, State of Rhode Island and Providence Plantations
    Inventor: Brenton DeBoef
  • AEROBIC OXIDATIVE COUPLING FOR THE FORMATION OF BIARYLS
    Publication number: 20090253921
    Abstract: A method of catalytic oxidative coupling for the formation of hetero-coupled bis-arenes. The method includes placing a solvent, an arene compound, and a catalyst in a reactor having a oxidant atmosphere such that hetero-coupled bis-arenes are formed.
    Type: Application
    Filed: April 30, 2009
    Publication date: October 8, 2009
    Applicant: BOARD OF GOVERNORS FOR HIGHER EDUCATION, STATE OF RHODE ISLAND AND PROVIDENCE
    Inventor: Brenton DeBoef