Patents by Inventor Bret M. Steiner

Bret M. Steiner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR DETECTING TREPONEMA PALLIDUM
    Publication number: 20080139783
    Abstract: Methods for the specific and highly sensitive detection of Treponema pallidum infection comprising the use of specific antigenic proteins and peptides unique to Treponema pallidum are provided. In particular, detection assays based on recognition of acidic repeat protein are provided. The methods of the present invention are useful for detection of primary syphilis at early stages of infection. In addition, the methods and compositions disclosed herein are directed to the differential detection of specific Treponema infections enabling the identification of causative agents for specific Treponema disease states: syphilis (Treponema pallidum subspecies pallidum), yaws (Treponema pallidum subspecies pertenue CDC-1 or CDC-2 strain), and bejel (Treponema pallidum subspecies endemicum).
    Type: Application
    Filed: December 26, 2007
    Publication date: June 12, 2008
    Inventors: Hsi Liu, Bret M. Steiner, Berta Rodes
  • Compositions and methods for detecting
    Patent number: 7335736
    Abstract: Methods for the specific and highly sensitive detection of Treponema pallidum infection comprising the use of specific antigenic proteins and peptides unique to Treponema pallidum are provided. In particular, detection assays based on recognition of acidic repeat protein are provided. The methods of the present invention are useful for detection of primary syphilis at early stages of infection. In addition, the methods and compositions disclosed herein are directed to the differential detection of specific Treponema infections enabling the identification of causative agents for specific Treponema disease states: syphilis (Treponema pallidum subspecies pallidum), yaws (Treponema pallidum subspecies pertenue CDC-1 or CDC-2 strain), and bejel (Treponema pallidum subspecies endemicum).
    Type: Grant
    Filed: September 6, 2005
    Date of Patent: February 26, 2008
    Assignee: The United State of America as represented by the Department of Health and Human Services
    Inventors: Hsi Liu, Bret M. Steiner, Berta Rodes
  • Compositions and methods for detecting
    Patent number: 7005270
    Abstract: Methods for the specific and highly sensitive detection of Treponema pallidum infection comprising the use of specific antigenic proteins and peptides unique to Treponema pallidum are provided. In particular, detection assays based recognition of acidic repeat protein are provided. The methods of the present invention are useful for detection of primary syphilis at early stages of infection. In addition, the methods and compositions disclosed herein are directed to the differential detection of specific Treponema infections enabling the identification of causative agents for specific Treponema disease states: syphilis (Treponema pallidum subspecies pallidum), yaws (Treponema pallidum subspecies pertenue CDC-1 or CDC-2 strain), and bejel (Treponema pallidum subspecies endemicum).
    Type: Grant
    Filed: December 14, 2001
    Date of Patent: February 28, 2006
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Hsi Liu, Bret M. Steiner, Berta Rodes