Patents by Inventor Bret Stephens

Bret Stephens has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11489364
    Abstract: Embodiments of the disclosure provide a method for controlling a power generation system during on-line maintenance. The method includes operating the power generation system in a first maintenance mode, which causes a controller of the power generation system to disable an automated response to at least one operational fault of the power generation system; monitoring a risk parameter of the power generation system or at least one sensor within the power generation system while operating the power generation system in the first maintenance mode; and operating the power generation system in a second maintenance mode in response to detecting an override command, an elapsed time exceeding a time limit, or the monitored risk parameter exceeding a safety threshold. The second maintenance mode causes the controller of the power generation system to enable the automated response to the at least one operational fault of the power generation system.
    Type: Grant
    Filed: July 22, 2020
    Date of Patent: November 1, 2022
    Assignee: General Electric Company
    Inventors: Bryan Edward Sweet, Christian-Anghel Solacolu, Melinda Stephanie Ammerman, Bret Stephen Dalton
  • Publication number: 20220029454
    Abstract: Embodiments of the disclosure provide a method for controlling a power generation system during on-line maintenance. The method includes operating the power generation system in a first maintenance mode, which causes a controller of the power generation system to disable an automated response to at least one operational fault of the power generation system; monitoring a risk parameter of the power generation system or at least one sensor within the power generation system while operating the power generation system in the first maintenance mode; and operating the power generation system in a second maintenance mode in response to detecting an override command, an elapsed time exceeding a time limit, or the monitored risk parameter exceeding a safety threshold. The second maintenance mode causes the controller of the power generation system to enable the automated response to the at least one operational fault of the power generation system.
    Type: Application
    Filed: July 22, 2020
    Publication date: January 27, 2022
    Inventors: Bryan Edward Sweet, Christian-Anghel Solacolu, Melinda Stephanie Ammerman, Bret Stephen Dalton
  • Publication number: 20210065146
    Abstract: A method of providing a user interface for a higher education community is provided. The method includes: (a) providing a user interface for use by each of a plurality of members of a higher education community; and (b) customizing the user interface for each of the plurality of members of the higher education community.
    Type: Application
    Filed: August 28, 2020
    Publication date: March 4, 2021
    Inventors: Kurt August Zarefoss, Mary-Anne Blodgett, Bret Stephen Hansen
  • Patent number: 9642857
    Abstract: Methods of treatment of disorders of uncontrolled cellular proliferation, including cancer, by administering substituted (E)-N?-(1-phenylethylidene)benzohydrazide analogs, derivatives thereof, and related compounds to mammals in need thereof.
    Type: Grant
    Filed: January 4, 2016
    Date of Patent: May 9, 2017
    Assignee: University of Utah Research Foundation
    Inventors: Hariprasad Vankayalapati, Venkataswamy Sorna, Steven L. Warner, Bret Stephens, David J. Bearss, Sunil Sharma
  • Patent number: 9555024
    Abstract: In one aspect, the invention relates to substituted (E)-N?-(1-phenylethylidene)benzohydrazide analogs, derivatives thereof, and related compounds, which are useful as inhibitors of lysine-specific histone demethylase, including LSD1; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds and compositions to treat disorders associated with dysfunction of the LSD1. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: February 16, 2015
    Date of Patent: January 31, 2017
    Assignee: University of Utah Research Foundation
    Inventors: Hariprasad Vankayalapati, Venkataswamy Sorna, Steven L. Warner, Bret Stephens, David J. Bearss, Sunil Sharma
  • Publication number: 20160120875
    Abstract: Methods of treatment of disorders of uncontrolled cellular proliferation, including cancer, by administering substituted (E)-N?-(1-phenylethylidene)benzohydrazide analogs, derivatives thereof, and related compounds to mammals in need thereof.
    Type: Application
    Filed: January 4, 2016
    Publication date: May 5, 2016
    Inventors: Hariprasad Vankayalapati, Venkataswamy Sorna, Steven L. Warner, Bret Stephens, David J. Bearss, Sunil Sharma
  • Patent number: 9266838
    Abstract: In one aspect, the invention relates to substituted (E)-N?-(1-phenylethylidene)benzohydrazide analogs, derivatives thereof, and related compounds, which are useful as inhibitors of lysine-specific histone demethylase, including LSD1; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds and compositions to treat disorders associated with dysfunction of the LSD1. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: June 19, 2013
    Date of Patent: February 23, 2016
    Assignee: University of Utah Research Foundation
    Inventors: Hariprasad Vankayalapati, Venkataswamy Sorna, Steven L. Warner, Bret Stephens, David J. Bearss, Sunil Sharma
  • Publication number: 20150150864
    Abstract: In one aspect, the invention relates to substituted (E)-N?-(1-phenylethylidene)benzohydrazide analogs, derivatives thereof, and related compounds, which are useful as inhibitors of lysine-specific histone demethylase, including LSD1; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds and compositions to treat disorders associated with dysfunction of the LSD1. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: February 16, 2015
    Publication date: June 4, 2015
    Applicant: UNIVERSITY OF UTAH RESEARCH FOUNDATION
    Inventors: Hariprasad Vankayalapati, Venkataswamy Sorna, Steven L. Warner, Bret Stephens, David J. Bearss, Sunil Sharma
  • Patent number: 8987335
    Abstract: In one aspect, the invention relates to substituted (E)-N?-(1-phenylethylidene)benzohydrazide analogs, derivatives thereof, and related compounds, which are useful as inhibitors of lysine-specific histone demethylase, including LSD1; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds and compositions to treat disorders associated with dysfunction of the LSD1. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: August 15, 2012
    Date of Patent: March 24, 2015
    Assignee: University of Utah Research Foundation
    Inventors: Hariprasad Vankayalapati, Venkataswamy Sorna, Steven L. Warner, Bret Stephens, David J. Bearss, Sunil Sharma
  • Patent number: 8756939
    Abstract: Embodiments of the present invention have the technical effect of automatically testing an overspeed protection system of a powerplant machine comprising at least one shaft. An embodiment of the present invention may automatically test the overspeed protection system while the powerplant machine is decelerating from full-speed-no-load (FSNL). Another embodiment of the present invention may automatically test the overspeed protection system of the powerplant machine while the powerplant machine is accelerating to FSNL.
    Type: Grant
    Filed: March 23, 2010
    Date of Patent: June 24, 2014
    Assignee: General Electric Company
    Inventors: Frederick William Block, Richard Lee Nichols, Joseph Robert Law, Bret Stephen Dalton, George Allen Ellis
  • Publication number: 20140163017
    Abstract: In one aspect, the invention relates to substituted (E)-N?-(1-phenylethylidene)benzohydrazide analogs, derivatives thereof, and related compounds, which are useful as inhibitors of lysine-specific histone demethylase, including LSD1; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds and compositions to treat disorders associated with dysfunction of the LSD1. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: June 19, 2013
    Publication date: June 12, 2014
    Applicant: UNIVERSITY OF UTAH
    Inventors: Hariprasad Vankayalapati, Venkataswamy Sorna, Steven L. Warner, Bret Stephens, David J. Bearss, Sunil Sharma
  • Publication number: 20140094445
    Abstract: In one aspect, the invention relates to substituted (E)-N?-(1-phenylethylidene)benzohydrazide analogs, derivatives thereof, and related compounds, which are useful as inhibitors of lysine-specific histone demethylase, including LSD1; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds and compositions to treat disorders associated with dysfunction of the LSD1. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: August 15, 2012
    Publication date: April 3, 2014
    Applicant: University of Utah Research Foundation
    Inventors: Hariprasad Vakayalapati, Venkataswamy Soma, Steven L. Warner, Bret Stephens, David J. Bearss, Sunil Sharma
  • Patent number: 8365583
    Abstract: Embodiments of the present invention have the technical effect of automatically testing an overspeed protection system of a powerplant machine comprising a shaft and integrated with a safety control system. An embodiment of the present invention may automatically test the overspeed protection system while the powerplant machine is in the process of shutting down. Another embodiment of the present invention may automatically test the overspeed protection system of the powerplant machine by adjusting the speed of a shaft while operating at full-speed-no-load.
    Type: Grant
    Filed: March 23, 2010
    Date of Patent: February 5, 2013
    Assignee: General Electric Company
    Inventors: Frederick William Block, Richard Lee Nichols, Bret Stephen Dalton, Jay Lynn Johnson, George Allen Ellis
  • Patent number: 8370100
    Abstract: Embodiments of the present invention have the technical effect of determining when to test an overspeed protection system of a powerplant machine. As described herein, embodiments of the present invention may be applied to a wide variety of powerplant machines, each comprising a shaft. After determining that test of the overspeed protection system should be performed, embodiments of the present invention may allow for a variety of methods to test the overspeed protection system.
    Type: Grant
    Filed: March 23, 2010
    Date of Patent: February 5, 2013
    Assignee: General Electric Company
    Inventors: Frederick William Block, Richard Lee Nichols, Joseph Robert Law, Bret Stephen Dalton, George Allen Ellis
  • Publication number: 20110232297
    Abstract: Embodiments of the present invention have the technical effect of automatically testing an overspeed protection system of a powerplant machine comprising at least one shaft. An embodiment of the present invention may automatically test the overspeed protection system while the powerplant machine is decelerating from full-speed-no-load (FSNL). Another embodiment of the present invention may automatically test the overspeed protection system of the powerplant machine while the powerplant machine is accelerating to FSNL.
    Type: Application
    Filed: March 23, 2010
    Publication date: September 29, 2011
    Inventors: Frederick William Block, Richard Lee Nichols, Joseph Robert Law, Bret Stephen Dalton, George Allen Ellis
  • Publication number: 20110238358
    Abstract: Embodiments of the present invention have the technical effect of determining when to test an overspeed protection system of a powerplant machine. As described herein, embodiments of the present invention may be applied to a wide variety of powerplant machines, each comprising a shaft. After determining that test of the overspeed protection system should be performed, embodiments of the present invention may allow for a variety of methods to test the overspeed protection system.
    Type: Application
    Filed: March 23, 2010
    Publication date: September 29, 2011
    Inventors: Frederick William Block, Richard Lee Nichols, Joseph Robert Law, Bret Stephen Dalton, George Allen Ellis
  • Publication number: 20110232259
    Abstract: Embodiments of the present invention have the technical effect of automatically testing an overspeed protection system of a powerplant machine comprising a shaft and integrated with a safety control system. An embodiment of the present invention may automatically test the overspeed protection system while the powerplant machine is in the process of shutting down. Another embodiment of the present invention may automatically test the overspeed protection system of the powerplant machine by adjusting the speed of a shaft while operating at full-speed-no-load.
    Type: Application
    Filed: March 23, 2010
    Publication date: September 29, 2011
    Inventors: Frederick William Block, Richard Lee Nichols, Bret Stephen Dalton, Jay Lynn Johnson, George Allen Ellis