Patents by Inventor Brett, A. Neilan

Brett, A. Neilan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Detection of saxitoxin-producing dinoflagellates
    Patent number: 10947601
    Abstract: The invention generally relates to the field of saxitoxins and the identification of microorganisms capable of producing them. More specifically, the invention relates to the identification of genes encoding saxitoxin in dinoflagellates, and methods for the specific detection of dinoflagellates that are producers of saxitoxins.
    Type: Grant
    Filed: December 6, 2016
    Date of Patent: March 16, 2021
    Assignees: EWSOUTH INNOVATIONS PTY LIMITED, UNIVERSITETET I OSLO
    Inventors: Brett A. Neilan, Shauna Ann Murray, Anke Stuken, Kjetill S. Jakobsen, Russel J. S. Orr, Ralf Kellmann
  • Cyanobacteria saxitoxin gene cluster and detection of cyanotoxic organisms
    Patent number: 10415097
    Abstract: The present invention provides methods for the detection of cyanobacteria, and in particular, methods for the detection of cyanotoxic organisms. The invention further relates to methods of screening for compounds that modulate the activity of polynucleotides and/or polypeptides of the saxitoxin biosynthetic pathways.
    Type: Grant
    Filed: November 16, 2015
    Date of Patent: September 17, 2019
    Assignee: Newsouth Innovations PTY Limited
    Inventors: Brett A. Neilan, Troco Kaan Mihali, Ralf Kellmann, Young Jae Jeon
  • DETECTION OF SAXITOXIN-PRODUCING DINOFLAGELLATES
    Publication number: 20170081733
    Abstract: The invention generally relates to the field of saxitoxins and the identification of microorganisms capable of producing them. More specifically, the invention relates to the identification of genes encoding saxitoxin in dinoflagellates, and methods for the specific detection of dinoflagellates that are producers of saxitoxins.
    Type: Application
    Filed: December 6, 2016
    Publication date: March 23, 2017
    Inventors: Brett A. Neilan, Shauna Ann Murray, Anke Stuken, Kjetill S. Jakobsen, Russel J. S. Orr, Ralf Kellmann
  • Detection of saxitoxin-producing dinoflagellates
    Patent number: 9580759
    Abstract: The current disclosure generally relates to the field of saxitoxins and the identification of microorganisms capable of producing them. In particular, the saxitoxin A (sxtA) gene comprising catalytic domain sequences saxitoxin A1 (sxtA1) and saxitoxin A4 (sxtA4) is identified in a number of dinoflagellate species. The disclosure relates to methods of detection of saxitoxin-producing dinoflagellates by amplification and detection of the sxtA gene (in particular by PCR) and kits and primers for use in the method are also disclosed. Saxitoxin-producing dinoflagellate genera detected by the method include Alexandrium, Pyrodinium or Gymnodinium.
    Type: Grant
    Filed: May 16, 2012
    Date of Patent: February 28, 2017
    Assignees: UNIVERSITETET I OSLO, NEWSOUTH INNOVATIONS PTY LIMITED
    Inventors: Brett A. Neilan, Shauna Ann Murray, Anke Corinna Stüken, Kjetill S. Jakobsen, Russel J. S. Orr, Ralf Kellmann
  • CYANOBACTERIA SAXITOXIN GENE CLUSTER AND DETECTION OF CYANOTOXIC ORGANISMS
    Publication number: 20160153030
    Abstract: The present invention provides methods for the detection of cyanobacteria, and in particular, methods for the detection of cyanotoxic organisms. The invention further relates to methods of screening for compounds that modulate the activity of polynucleotides and/or polypeptides of the saxitoxin biosynthetic pathways.
    Type: Application
    Filed: November 16, 2015
    Publication date: June 2, 2016
    Inventors: Brett A. NEILAN, Troco Kaan MIHALI, Ralf KELLMANN, Young Jae JEON
  • Methods for producing secondary metabolites
    Patent number: 9115359
    Abstract: The invention relates to methods for producing secondary metabolites using transformed Synechocystis sp. bacteria, and secondary metabolites produced by transformed Synechocystis sp. bacteria. The invention further relates to phosphopantetheinyl transferase enzymes.
    Type: Grant
    Filed: April 2, 2008
    Date of Patent: August 25, 2015
    Assignee: NewSouth Innovations Pty Limited
    Inventors: Brett A. Neilan, Alex Roberts, Janine Copp
  • Detection of hepatotoxic cyanobacteria
    Patent number: 8927217
    Abstract: The present invention relates to methods and kits for the detection of toxic cyanobacteria, in particular of hepatotoxin-producing cyanobacteria.
    Type: Grant
    Filed: May 31, 2006
    Date of Patent: January 6, 2015
    Assignee: NewSouth Innovations Pty Limited
    Inventors: Brett A. Neilan, Anne-Dorothee Jungblut
  • DETECTION OF SAXITOXIN-PRODUCING DINOFLAGELLATES
    Publication number: 20140113301
    Abstract: The current disclosure generally relates to the field of saxitoxins and the identification of microorganisms capable of producing them. In particular, the saxitoxin A (sxtA) gene comprising catalytic domain sequences saxitoxin A1 (sxtA1) and saxitoxin A4 (sxtA4) is identified in a number of dinoflagellate species. The disclosure relates to methods of detection of saxitoxin-producing dinoflagellates by amplification and detection of the sxtA gene (in particular by PCR) and kits and primers for use in the method are also disclosed. Saxitoxin-producing dinoflagellate genera detected by the method include Alexandrium, Pyrodinium or Gymnodinium.
    Type: Application
    Filed: May 16, 2012
    Publication date: April 24, 2014
    Applicants: UNIVERSITETET I OSLO, NEWSOUTH INNOVATIONS PTY LIMITED
    Inventors: Brett A. Neilan, Shauna Ann Murray, Anke Stuken, Kjetill S. Jakobsen, Russel J. S. Orr, Ralf Kellmann
  • CYANOBACTERIA SAXITOXIN GENE CLUSTER AND DETECTION OF CYANOTOXIC ORGANISMS
    Publication number: 20110129842
    Abstract: The present invention relates to methods for the detection of cyanobacteria, dinoflagellates, and in particular, methods for the detection of cyanotoxic organisms. Kits for the detection of cyanobacteria, dinoflagellates, and cyanotoxic organisms are provided. The invention further relates to methods of screening for compounds that modulate the activity of polynucleotides and/or polypeptides of the saxitoxin and cylindrospermopsin biosynthetic pathways.
    Type: Application
    Filed: December 5, 2008
    Publication date: June 2, 2011
    Applicant: NEWSOUTH INNOVATIONS PTY LIMITED
    Inventors: Brett A. Neilan, Troco Kaan Mihali, Ralf Kellmann, Young Jae Jeon
  • METHODS FOR PRODUCING SECONDARY METABOLITES
    Publication number: 20100261218
    Abstract: The invention relates to methods for producing secondary metabolites using transformed Synechocystis sp. bacteria, and secondary metabolites produced by transformed Synechocystis sp. bacteria. The invention further relates to phosphopantetheinyl transferase enzymes.
    Type: Application
    Filed: April 2, 2008
    Publication date: October 14, 2010
    Applicant: NEWSOUTH INNOVATIONS PTY LIMITED
    Inventors: Brett, A. Neilan, Alex Roberts, Janine Copp